ChemicalBook > CAS DataBase List > 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol

2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol

Product Name: 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol
CAS No.: 3621-38-3
Chemical Name: 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol
Synonyms: Neprotin;Neprotine;Yatrorizine;Jatrorrhizin;Jateorhizine;Jateorrhizine;jatrorrhizine;NEPROTINE HCL;YATROIZINE HCL;JATRORRHIZINE(P)
CBNumber: CB5203211
Molecular Formula: C20H20INO4
Formula Weight: 465.28
MOL File: 3621-38-3.mol

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2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol Property

Melting point:: 208～210℃
storage temp.: Inert atmosphere,2-8°C
solubility: Methanol (Slightly, Heated)
form: Solid
color: Orange
Stability:: Hygroscopic
InChIKey: MXTLAHSTUOXGQF-UHFFFAOYSA-O

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Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: J4705
Product name: Jatrorrhizine
Purity: from Tinospora sagittata, ≥95% (HPLC)
Packaging: 50MG
Price: $962
Updated: 2022/05/15

Usbiological

Product number: 361814
Product name: Jatrorrhizine
Packaging: 20mg
Price: $335
Updated: 2021/12/16

Usbiological

Product number: 300512
Product name: Jatrorrhizine chloride
Packaging: 20mg
Price: $335
Updated: 2021/12/16

ChemScene

Product number: CS-0009780
Product name: Jatrorrhizine
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0009780
Product name: Jatrorrhizine
Packaging: 10mg
Price: $80
Updated: 2021/12/16

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2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol Chemical Properties,Usage,Production

Description

An alkaloid from Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng), this base is optically inactive and forms garnet-red crystals which decompose on heat_x0002_ing. The base contains 3.5 mole of H20 and still retains 1 mole even or prolonged drying at 100°C in vacuo. The salts are said to be orange or yellow.

Uses

Jatrorrhizine, is an alkaloid extract from the Berberidaceae family of plants displaying antioxidant activity.

Definition

ChEBI: Jatrorrhizine is an alkaloid.

in vivo

Jatrorrhizine (intraperitoneal?injection; 5, 10, 20 mg/kg) can significantly reduce the duration of immobility when compared with vehicle control group in tail suspension test (TST)^[2].

Animal Model:	Male ICR albino mice^[2]
Dosage:	5, 10, 20 mg/kg
Administration:	Intraperitoneal?injection; 5, 10, 20 mg/kg
Result:	Reduced immobility period in tail suspension test.

target

LDL | P450 (e.g. CYP17) | NOS | COX | 5-HT Receptor | HMG-CoA Reductase

IC 50

AChE

References

Chatterjee., Sci. & Cult., 7,619 (1942)
Chatterjee.,J. Amer. Pharm. Assoc., 33,205,210 (1944)

2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol manufacturers

Wuhan Nutra Biotechnology Co.,Ltd

Product: Jatrorrhizine Hydrochloride 3621-38-3
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 10kgs
Release date: 2021-05-24

Shaanxi Dideu Medichem Co. Ltd

Product: Jatrorrhizine 3621-38-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20t
Release date: 2024-07-15

ANHUI WITOP BIOTECH CO., LTD

Product: Jatrorrhizine 3621-38-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 10ton
Release date: 2021-03-19

3621-38-3, 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-olRelated Search:

Berberine Palmatine Resveratrol CORYPALMINE, (+)-(P) (R)-(+)-Corypalmine JATRORRHIZINE HCL(RG) Dehydrocorydaline nitrate BERBERINE CHLORIDE Palmatine chloride hydrate BERBERINE ACID SULFATE Dehydrocorydaline Palmatine chloride BERBERINE CHLORIDE DIHYDRATE 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol BERBERINE SULFATE TRIHYDRATE PALMATINE IODIDE AKOS 213-46 BERBERINE, ACETONE ADDUCT

Jatrorrhizin

2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol

2,9,10-trimethoxy-

Dibenzo[a,g]quinolizinium, 5,6-dihydro-3-hydroxy-

Neprotin

Neprotine

Yatrorizine

5,6-Dihydro-3-hydroxy-2,9,10-trimethoxyberbinium

5,6-Dihydro-3-hydroxy-2,9,10-trimethoxydibenzo[a,g]quinolizinium

Jateorhizine

Jateorrhizine

JATRORRHIZINE(P)

DehydrocorypalMine

3-Hydroxy-2,9,10-trimethoxy-5,6-dihydroisoquinolino-[3,2-a]isoquinolin-7-ium

jatrorrhizine

JATRORRHIZINE STANDARD 98+% BY HPLC

JATRORRHIZINE CHLORIDE

JATRORRHIZINE HCL

JATRORRHIZINE IODIDE

Jatrorrhizine 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol

7,8,13,13α-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium

NEPROTINE HCL

NEPROTINE IODIDE

YATROIZINE HCL

YATROIZINE IODIDE

Jatrorrhizine iodide, 98%, from Mahonia fortunei (Lindl.) Fedde

2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol USP/EP/BP

Jatrorrhizine See J210900 or J210910

3621-38-3

C20H20NO4Cl

Alkaloids