Dehydrocorydaline
- Product Name
- Dehydrocorydaline
- CAS No.
- 30045-16-0
- Chemical Name
- Dehydrocorydaline
- Synonyms
- Dehydrocorydaline;dehydeocorydaline;13-Methylpalmatine;DEHYDROCORYDALINE98%;acetate salt of Dehydrocorydaline;5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium;13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium;Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-;2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium
- CBNumber
- CB61178432
- Molecular Formula
- C22H24NO4
- Formula Weight
- 0
- MOL File
- 30045-16-0.mol
Dehydrocorydaline Property
- Melting point:
- 170-173℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Cryst.
- color
- Light yellow to yellow
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H304May be fatal if swallowed and enters airways
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P331Do NOT induce vomiting.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- SML3501
- Product name
- Dehydrocorydaline
- Purity
- ≥98% (HPLC)
- Packaging
- 5MG
- Price
- $79
- Updated
- 2023/01/07
- Product number
- SML3501
- Product name
- Dehydrocorydaline
- Purity
- ≥98% (HPLC)
- Packaging
- 25MG
- Price
- $319
- Updated
- 2023/01/07
- Product number
- 361773
- Product name
- Dehydrocorydaline
- Packaging
- 10mg
- Price
- $439
- Updated
- 2021/12/16
- Product number
- N2090
- Product name
- 2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
- Packaging
- 20mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- FD73994
- Product name
- Dehydrocorydaline
- Packaging
- 100mg
- Price
- $500
- Updated
- 2021/12/16
Dehydrocorydaline Chemical Properties,Usage,Production
Chemical Properties
Yellow needle crystal powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Corydalis Corydalis, Yuanhu.
Uses
Dehydrocordine has analgesic and sedative effects. It was used for content determination/identification/pharmacological experiments, etc.
Definition
ChEBI: Dehydrocorydaline is an alkaloid.
Biological Activity
Dehydrocorydaline (13-Methylpalmatine) is an alkaloid isolated from the traditional Chinese medicine Corydalis yanhusuo. It can enhance p38 MAPK activation and has anti-inflammatory and anti-cancer effects. Also Dehydrocorydaline has potent antimalarial effects and low cytotoxicity (cell viability > 90%), P. falciparum 3D7 strain (IC50=38 nM).
in vitro
Dehydrocorydaline (0-200 μM) treatment significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. The cell viability is decreased by approximate 40% after 24 h of 200 μM Dehydrocorydaline.
Dehydrocorydaline (0-200 μM) dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression.
Dehydrocorydaline (0-200 μM) induces activation of caspase-7,-8 and the cleavage of PARP without affecting caspase-9.
in vivo
Dehydrocorydaline manifests a low acute toxicity with an LD 50 of about 277.5±19.0 mg/kg body weight in mice following oral administration and 21.1±1.4 mg/kg for intraperitoneal injection. < /p>
target
| Bcl-2 < span> | Bax
| Caspase-7
| Caspase-8
| PARP
|
Dehydrocorydaline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dehydrocorydaline manufacturers
- Product
- Dehydrocorydaline 30045-16-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-24
- Product
- Dehydrocorydaline 30045-16-0
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥95%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-04
- Product
- Dehydrocorydaline 30045-16-0
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10