ChemicalBook > CAS DataBase List > Dehydrocorydaline

Dehydrocorydaline

Product Name
Dehydrocorydaline
CAS No.
30045-16-0
Chemical Name
Dehydrocorydaline
Synonyms
Dehydrocorydaline;dehydeocorydaline;13-Methylpalmatine;DEHYDROCORYDALINE98%;acetate salt of Dehydrocorydaline;5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium;13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium;Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-;2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium
CBNumber
CB61178432
Molecular Formula
C22H24NO4
Formula Weight
0
MOL File
30045-16-0.mol
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Dehydrocorydaline Property

Melting point:
170-173℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3501
Product name
Dehydrocorydaline
Purity
≥98% (HPLC)
Packaging
5MG
Price
$79
Updated
2023/01/07
Sigma-Aldrich
Product number
SML3501
Product name
Dehydrocorydaline
Purity
≥98% (HPLC)
Packaging
25MG
Price
$319
Updated
2023/01/07
Usbiological
Product number
361773
Product name
Dehydrocorydaline
Packaging
10mg
Price
$439
Updated
2021/12/16
ApexBio Technology
Product number
N2090
Product name
2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
Packaging
20mg
Price
$450
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD73994
Product name
Dehydrocorydaline
Packaging
100mg
Price
$500
Updated
2021/12/16
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Dehydrocorydaline Chemical Properties,Usage,Production

Chemical Properties

Yellow needle crystal powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Corydalis Corydalis, Yuanhu.

Uses

Dehydrocordine has analgesic and sedative effects. It was used for content determination/identification/pharmacological experiments, etc.

Definition

ChEBI: Dehydrocorydaline is an alkaloid.

Biological Activity

Dehydrocorydaline (13-Methylpalmatine) is an alkaloid isolated from the traditional Chinese medicine Corydalis yanhusuo. It can enhance p38 MAPK activation and has anti-inflammatory and anti-cancer effects. Also Dehydrocorydaline has potent antimalarial effects and low cytotoxicity (cell viability > 90%), P. falciparum 3D7 strain (IC50=38 nM).

in vitro

Dehydrocorydaline (0-200 μM) treatment significantly inhibits the growth of MCF-7 cells in a dose-dependent manner. The cell viability is decreased by approximate 40% after 24 h of 200 μM Dehydrocorydaline.
Dehydrocorydaline (0-200 μM) dose-dependently increases Bax protein expression and decreases Bcl-2 protein expression.
Dehydrocorydaline (0-200 μM) induces activation of caspase-7,-8 and the cleavage of PARP without affecting caspase-9.

in vivo

Dehydrocorydaline manifests a low acute toxicity with an LD 50 of about 277.5±19.0 mg/kg body weight in mice following oral administration and 21.1±1.4 mg/kg for intraperitoneal injection. < /p>

target

Bcl-2

< span>

Bax

Caspase-7

Caspase-8

PARP

Dehydrocorydaline Preparation Products And Raw materials

Raw materials

Preparation Products

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Dehydrocorydaline Suppliers

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View Lastest Price from Dehydrocorydaline manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Dehydrocorydaline 30045-16-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-24
Shanghai Standard Technology Co., Ltd.
Product
Dehydrocorydaline 30045-16-0
Price
US $0.00/mg
Min. Order
5mg
Purity
≥95%(HPLC)
Supply Ability
10 g
Release date
2019-12-04
Zhuozhou Wenxi import and Export Co., Ltd
Product
Dehydrocorydaline 30045-16-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

30045-16-0, DehydrocorydalineRelated Search:

Protopine VERATRIDINE Tetrahydropalmatine Daurinoline corydalmine Tetrahydroberberine Xanthiside 2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one daurisoline menisdaurin Dehydrohydrogen fumarate 2,9,10-Trimethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium-3-ol Palmatine Dehydrocorydaline nitrate Dehydrocorydaline columbamine 3-PHENYLISOQUINOLINE 4-(Isoquinolin-3-yl)phenol

  • 13-Methylpalmatine
  • dehydeocorydaline
  • Dehydrocorydaline
  • DEHYDROCORYDALINE98%
  • 13-Methyl-2,3,9,10-tetramethoxy-5,6-dihydrodibenzo[a,g]quinolizinium
  • 5,6-Dihydro-2,3,9,10-tetramethoxy-13-methyldibenzo[a,g]quinolizinium
  • Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-13-methyl-
  • acetate salt of Dehydrocorydaline
  • 2,3,9,10-tetramethoxy-13-methyl-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
  • Parasite,Caspase,Bcl-2 Family,Dehydrocorydaline,inhibit,Inhibitor,p38 MAPK,Autophagy,PARP,poly ADP ribose polymerase
  • 2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium
  • 30045-16-0
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract