4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
- Product Name
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
- CAS No.
- 33097-11-9
- Chemical Name
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
- Synonyms
- ASISCHEM C51986;2-Aminomethylimidazoledihydrochloride;4,6-DICHLORO-2-(METHYLTHIO)-5-FORMYLPYRIMIDINE;2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-Dichloro-5-formyl-2-(methylthio)pyrimidine;4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARB;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarbaldehyde;4,6-Dichloro-2-(methylthio)pyrimidine-5-carbaldehyde;2-(Methylthio)-4,6-dichloropyriMidine-5-carboxaldehyde;4,6-Dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde
- CBNumber
- CB5225675
- Molecular Formula
- C6H4Cl2N2OS
- Formula Weight
- 223.08
- MOL File
- 33097-11-9.mol
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Property
- Melting point:
- 82-84°C
- Boiling point:
- 327.7±37.0 °C(Predicted)
- Density
- 1.57±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Chloroform, Ether, Ethyl Acetate
- form
- Solid
- pka
- -6.47±0.39(Predicted)
- color
- Pale Yellow
- InChI
- InChI=1S/C6H4Cl2N2OS/c1-12-6-9-4(7)3(2-11)5(8)10-6/h2H,1H3
- InChIKey
- MRHGOAKYYORQGQ-UHFFFAOYSA-N
- SMILES
- C1(SC)=NC(Cl)=C(C=O)C(Cl)=N1
N-Bromosuccinimide Price
- Product number
- 759279
- Product name
- 4,6-Dichloro-2-(methylthio)pyrimidine-5-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $72
- Updated
- 2023/06/20
- Product number
- D435570
- Product name
- 4,6-Dichloro-2-(methylthio)-5-formylpyrimidine
- Packaging
- 10g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- W5479
- Product name
- 4,6-Dichloro-2-(methylthio)pyrimidine-5-carbaldehyde
- Packaging
- 5g
- Price
- $147
- Updated
- 2021/12/16
- Product number
- FD09667
- Product name
- 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine
- Packaging
- 2g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FD09667
- Product name
- 2,4-Dichloro-5-formyl-2-(methylthio)pyrimidine
- Packaging
- 10g
- Price
- $380
- Updated
- 2021/12/16
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
4,6-Dichloro-2-(methylthio)-5-formylpyrimidine (cas# 33097-11-9) is a compound useful in organic synthesis.
Synthesis
1979-98-2
33097-11-9
The general procedure for the synthesis of 4,6-dichloro-2-methylthiopyrimidine-5-carbaldehyde from 4,6-dihydroxy-2-methylthiopyrimidine was as follows: the reaction system was cooled down to 0-10 °C and then slowly warmed up to room temperature. Subsequently, 6-hydroxy-2-(methylthio)-4(1H)-pyrimidinone (25 g, 0.16 mol) was added in batches. The reaction mixture was heated and reacted at 80 °C overnight. After completion of the reaction, the reaction mixture was concentrated under vacuum. The concentrated slurry residue was poured into ice and stirred continuously for about 2 hours, after which filtration was performed to obtain the crude product. The crude product was further purified by recrystallization with hexane to afford finally 4,6-dichloro-2-(methylthio)-5-pyrimidinecarboxaldehyde (21.3 g, 61% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ 2.66 (s, 3H), 10.4 (s, 1H).
References
[1] Patent: WO2006/104889, 2006, A2. Location in patent: Page/Page column 113-114
[2] Patent: WO2007/147103, 2007, A2. Location in patent: Page/Page column 107-108
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE Suppliers
- Tel
- --
- Fax
- --
- export@ecochem.dk
- Country
- Europe
- ProdList
- 6371
- Advantage
- 66
- Tel
- --
- Fax
- --
- Sales@kemikalieimport.dk
- Country
- Europe
- ProdList
- 6685
- Advantage
- 47
View Lastest Price from 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE manufacturers
- Product
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE 33097-11-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-14
- Product
- 4,6-DICHLORO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE 33097-11-9
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-08