ChemicalBook > CAS DataBase List > N-Methyl-2-thiazolamine

N-Methyl-2-thiazolamine

Product Name
N-Methyl-2-thiazolamine
CAS No.
6142-06-9
Chemical Name
N-Methyl-2-thiazolamine
Synonyms
N-Methylthiazol-2-aMine;N-Methyl-2-thiazolamine;N-Methyl-2-aminothiazole;2-Thiazolamine, N-methyl-;Methyl-thiazol-2-yl-aMine
CBNumber
CB52491050
Molecular Formula
C4H6N2S
Formula Weight
114.17
MOL File
6142-06-9.mol
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N-Methyl-2-thiazolamine Property

Boiling point:
174.5±23.0 °C(Predicted)
Density 
1.246±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
5.38±0.10(Predicted)
form 
liquid
color 
Brown
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Safety

HS Code 
2934100090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Ark Pharm
Product number
P000159522
Product name
N-Methyl-2-thiazolamine
Purity
95+%
Packaging
250mg
Price
$58
Updated
2021/12/16
ChemScene
Product number
CS-W006616
Product name
N-Methyl-2-thiazolamine
Purity
≥97.0%
Packaging
1g
Price
$108
Updated
2021/12/16
AK Scientific
Product number
W7369
Product name
N-methyl-2-Thiazolamine
Packaging
250mg
Price
$117
Updated
2021/12/16
Ark Pharm
Product number
P000159522
Product name
N-Methyl-2-thiazolamine
Purity
95+%
Packaging
1g
Price
$120
Updated
2021/12/16
Apolloscientific
Product number
OR964710
Product name
N-Methyl-2-thiazolamine
Purity
97%
Packaging
250mg
Price
$145
Updated
2021/12/16
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N-Methyl-2-thiazolamine Chemical Properties,Usage,Production

Synthesis

3034-53-5

74-89-5

6142-06-9

Synthesis of exemplary compound 14: N-methyl-N-(2-(methyl(thiazol-2-yl)amino)-2-oxoethyl)-3-phenylpropanamide; a) Synthesis of N-methylthiazol-2-amine; 900 μL (10 mmol) of 2-bromothiazole in 33% w/w ethanol methylamine solution (70 mL) was placed in an autoclave and heated to about 120 °C until system pressure The reaction mixture was stirred continuously for 2 h under these conditions. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was dissolved in a 3% w/v aqueous hydrochloric acid solution. The aqueous phase was subsequently washed with ether and the pH was adjusted to 12 with 20% w/v aqueous sodium hydroxide. the aqueous phase was saturated with sodium chloride and extracted with chloroform. The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 761 mg (6.7 mmol, 67% yield) of N-methylthiazol-2-amine.

References

[1] Patent: US2009/176756, 2009, A1. Location in patent: Page/Page column 50

N-Methyl-2-thiazolamine Preparation Products And Raw materials

Raw materials

Preparation Products

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