ChemicalBook > CAS DataBase List > DISIALOGANGLIOSIDE GD1B 2NA

DISIALOGANGLIOSIDE GD1B 2NA

Product Name: DISIALOGANGLIOSIDE GD1B 2NA
CAS No.: 19553-76-5
Chemical Name: DISIALOGANGLIOSIDE GD1B 2NA
Synonyms: Gd1b;GD1B 2NA;Aids002546;Aids-002546;Ganglioside G2;Ganglioside C1;Ganglioside giii;GD1B-GANGLIOSIDE;GD1B (NH4+ SALT);ganglioside, GD1b
CBNumber: CB5253296
Molecular Formula: C84H148N4O40
Formula Weight: 1854.08
MOL File: 19553-76-5.mol

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DISIALOGANGLIOSIDE GD1B 2NA Property

storage temp.: −20°C
solubility: Chloroform:Methanol:DI Water (2:1:0.1): soluble
form: lyophilized powder

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 10-21
HS Code: 29400090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G8146
Product name: Disialoganglioside GD1b from bovine brain
Purity: ~95%
Packaging: 1mg
Price: $322
Updated: 2025/07/31

Cayman Chemical

Product number: 19569
Product name: Ganglioside GD1b (sodium salt)
Purity: ≥98%
Packaging: 1mg
Price: $141
Updated: 2024/03/01

Usbiological

Product number: 297011
Product name: GD1b-Ganglioside
Packaging: 1mg
Price: $523
Updated: 2021/12/16

TRC

Product number: G235073
Product name: GangliosideGD1bDisodiumSalt(BovineBrain)
Packaging: 1mg
Price: $560
Updated: 2021/12/16

Adipogen Life Sciences

Product number: AG-CN2-9004-M001
Product name: GangliosideGD1b.disodiumsalt
Purity: ≥98%(TLC)
Packaging: 1mg
Price: $150
Updated: 2021/12/16

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DISIALOGANGLIOSIDE GD1B 2NA Chemical Properties,Usage,Production

Description

Ganglioside G_D1b is an acidic glycosphingolipid that contains two sialic acid residues linked to an inner galactose unit. It is a component of plasma membranes where it packs densely with cholesterol to form lipid microdomains that modulate both intra- and intercellular signaling events. The concentration of ganglioside G_D1b in human brain increases with age, constituting 7.85% of total sialic acid in the brain of 0- to 10-year-old subjects and 20.29% in 11- to 30-year-old subjects. Ganglioside G_D1b levels are positively correlated with pilocytic astrocytoma tumor grade, and G_D1b has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas. Ganglioside G_D1b mixture contains ganglioside G_D1b molecular species with C18:1 and C20:1 fatty acyl chains.

Uses

Ganglioside GD1b Disodium Salt (Bovine Brain) is a ganglioside, major constituents of neuronal cell membranes and endoplasmic reticulum that have been shown to modulate cell signal transduction.

General Description

Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum; contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage; for classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.

Biochem/physiol Actions

May act as a bacterial toxin receptor (tetanus, botulinus); high levels found in gliomas and astrocytomas.

References

[1] L RIBONI. Natural occurrence of ganglioside lactones. Isolation and characterization of GD1b inner ester from adult human brain.[J]. The Journal of Biological Chemistry, 1986, 261 18: 8514-8519.
[2] T. COMAS. Immunohistochemical staining for ganglioside GD1b as a diagnostic and prognostic marker for primary human brain tumors.[J]. Neuro-oncology, 1999, 1 4 1: 261-267. DOI: 10.1093/neuonc/1.4.261

DISIALOGANGLIOSIDE GD1B 2NA Preparation Products And Raw materials

Raw materials

Preparation Products

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DISIALOGANGLIOSIDE GD1B 2NA Suppliers

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View Lastest Price from DISIALOGANGLIOSIDE GD1B 2NA manufacturers

GlycoPharm.LLC

Product: Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:?GD1b 19553-76-5
Price: US $0.00/test
Min. Order: 5test
Purity: 97%HPLC
Supply Ability: MG-KG
Release date: 2020-03-17

19553-76-5, DISIALOGANGLIOSIDE GD1B 2NARelated Search:

Tris(2,4-pentanedionato)chroMiuM(III) Aluminum acetylacetonate METHYL ISOCYANOACETATE N-BUTYLISOCYANIDE TERT-BUTYL ISOCYANIDE Benzyl isocyanide Ferric acetylacetonate Tosylmethyl isocyanide DISIALOGANGLIOSIDE GD1B 2NA 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Cupric acetylacetonate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) PHENYLSELENOL Ethyl isocyanoacetate TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE SALCOMINE

Ganglioside GD1b, Disialo, Diammonium Salt, Bovine Brain

ganglioside gd1b, disialo

GANGLIOSIDEGD1BDISODIUMSALT,BOVINEBRAIN

ganglioside, GD1b

Aids002546

Aids-002546

Ganglioside C1

Ganglioside G2

Ganglioside G2 (hexasaccharide)

Ganglioside gd1B polysaccharide

Ganglioside giii

Gd1b

GAL-BETA1,3GALNAC-BETA1,4(NEU5AC-ALPHA2,8)(NEU5AC-ALPHA2,3)GAL-BETA1,1' CERAMIDE

GALBETA1,3GALNACBETA1,4(NEU5ACALPHA2,8)(NEU5ACALPHA2,3)GALBETA1-4GLCBETA1,1' CERAMIDE

GAL-BETA1,3GALNAC-BETA1,4(NEU5AC-ALPHA2,8)(NEU5AC-ALPHA2,3)GAL-BETA1-4GLC-BETA1,1' CERAMIDE, HUMAN

GANGLIOSIDE GD1B, DISIALO, DIAMMONIUM SALT, BOVINE

GANGLIOSIDE GD1B, DISIALO, HUMAN

GANGLIOSIDE GD1B, DISIALO, HUMAN BRAIN

GANGLIOSIDE GD1B DISODIUM SALT

GD1B 2NA

GD1B-GANGLIOSIDE

GD1B (NH4+ SALT)

II3(NEU5AC)2GGOSE4 CERAMIDE, 2NH4, BOVINE

II3(NEU5NAC)2GGOSE4 CERAMIDE

II3(NEU5NAC)2GGOSE4 CERAMIDE, HUMAN

II3(NEUAC)2-GGOSE4CER

DISIALOGANGLIOSIDE-GD1B

DISIALOGANGLIOSIDE GD1B 2NA

Ganglioside GD1b (sodium salt)

GD1b-Ganglioside sodium

Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide Synonym:GD1b

DISIALOGANGLIOSIDE GD1B, BOVINE

DISIALOGANGLIOSIDE GD1B, HUMAN

DISIALOGANGLIOSIDE GD1B (NH4+ SALT)

Ganglioside GD1b Mixture (sodium salt)

GD1b ganglioside disodium salt (bovine brain)

MONOSIALOGANGLIOSIDE GD1B DISODIUM SALT

disialoganglioside G(D1B) from bovine brain

beta-Gal-(1->3)-beta-GalNAc-(1->4)-[alpha-Neu5Ac-(2->8)-alpha-Neu5Ac-(2->3)]-beta-Gal-(1->4)-beta-Glc-(1<->1')-Cer

Neu5Acα2, 8Neu5Acα2, 3(Galβ1, 3GalNAcβ1, 4)Galβ1, 4Glc Ceramide

Ganglioside GD1b Mixture (porcine brain) (ammonium salt)

Neu5Aca2,8Neu5Aca2,3(Galb1,3GalNAcb1,4)Galb1,4Glc Ceramide

Disialoganglioside GD<sub>1b</sub> from bovine brain

GD1b-Ganglioside ammonium

19553-76-5

C67H113N4O39R