BrettPhosPalladacycle

ChemicalBook > CAS DataBase List > BrettPhosPalladacycle

Reaction

Product Name: BrettPhosPalladacycle
CAS No.: 1148148-01-9
Chemical Name: BrettPhosPalladacycle
Synonyms: BrettPhos Pd G1;BrettPhos precatalyst;BrettPhos Palladacycle;BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct;BrettPhos Pd G1 MTBE adduct;BrettPhos Palladacycle Gen. 1;chloro-(2-phenylethylamino)palladium;[2-(2-aminoethyl)phenyl]palladium(1+);(BrettPhos) palladium(II) phenethylamine chloride;Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-...
CBNumber: CB52614378
Molecular Formula: C43H63ClNO2PPd
Formula Weight: 798.83
MOL File: 1148148-01-9.mol

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BrettPhosPalladacycle Property

Melting point:: 198-204 °C
form: Powder
color: white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 718750
Product name: BrettPhos Pd G1, Methyl t-Butyl Ether Adduct
Purity: may contain up to 1 mole equivalent of MTBE, 97%
Packaging: 1g
Price: $533
Updated: 2024/03/01

Sigma-Aldrich

Product number: 718750
Product name: BrettPhos Pd G1, Methyl t-Butyl Ether Adduct
Purity: may contain up to 1 mole equivalent of MTBE, 97%
Packaging: 5g
Price: $1450
Updated: 2024/03/01

Strem Chemicals

Product number: 46-0267
Product name: Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II), min. 98% [BrettPhos Palladacycle Gen. 1]
Packaging: 100mg
Price: $62
Updated: 2024/03/01

Strem Chemicals

Product number: 46-0267
Product name: Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II), min. 98% [BrettPhos Palladacycle Gen. 1]
Packaging: 500mg
Price: $180
Updated: 2024/03/01

Sigma-Aldrich

Product number: 718750
Product name: BrettPhos Pd G1, Methyl t-Butyl Ether Adduct
Purity: may contain up to 1 mole equivalent of MTBE, 97%
Packaging: 100mg
Price: $34.96
Updated: 2024/03/01

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BrettPhosPalladacycle Chemical Properties,Usage,Production

Reaction

Catalyst for cross-coupling reactions using aryl mesylates with electron-deficient anilines.
Catalyst for rapid C-N bond-forming processes at low catalyst loading.
Cross-coupling of 3-Bromo-2-aminopyridine with primary amines.

Uses

Application Guide for Palladium Catalyzed Cross-Coupling Reactions

Catalyst for:

C,N-cross coupling of unprotected 3-halo-2-aminopyridines with primary and secondary amines
Amination reaction
N-arylation of aminophenols

General Description

BrettPhos Pd G1 is a Buchwald first generation (G1) palladacycle precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. The formation of the active Pd(0) species in the G1 precatalyst is easy to generate, requiring merely a deprotonation with a base. The resulting catalyst is very active, even at temperatures down to ?40 °C, and can be used in a variety of cross-coupling protocols.

BrettPhosPalladacycle Preparation Products And Raw materials

Raw materials

Preparation Products

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BrettPhosPalladacycle Suppliers

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View Lastest Price from BrettPhosPalladacycle manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II) 1148148-01-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2020-04-21

Wuhan LPBchem Technology Co.,Ltd

Product: Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) /BrettPhos Pd G1 1148148-01-9
Price: US $10.00-10.00/g
Min. Order: 1g
Purity: 0.98
Supply Ability: 50kg
Release date: 2020-09-27

Career Henan Chemical Co

Product: Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) 1148148-01-9
Price: US $1.00/g
Min. Order: 1g
Purity: Min98%
Supply Ability: g/kg/ton
Release date: 2020-01-10

1148148-01-9, BrettPhosPalladacycleRelated Search:

Chloro(2-dicyclohexylphosphino-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-aMino-1,1'-biphenyl-2-yl)palladiuM(II), Min. 98% [BrettPhos Palladacycle] XPhos Pd G3 SPhos Palladacycle Gen. 4 XPhos Pd G4 Xantphos Pd G3 BrettPhos Pd G3 XPhos Pd G2 RuPhos Pd G1 Methyl t--Butyl Ether Adduct SPhos Pd G2 Palladacycle Gen. 3 t-BuXphos Palladacycle Gen. 4 RuPhos Palladacycle Gen. 4 t-BuBrettPhos Palladacycle Gen. 3 SPhos Pd G3 SPhos Pd G1, Methyl t-Butyl Ether Adduct RuPhos Pd G2 tBuXPhos Pd G1 XPhos Pd G1

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)

Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II),98%

BrettPhos Pd G1 Methyl-t-Butyl Ether Adduct

Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II), Min. 98% [BrettPhos Palladacycle]

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoeth

Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-Minoethyl)phenyl]palladiuM(II),Min.98%[BrettPhosPalladacycle]

(BrettPhos) palladium(II) phenethylamine chloride

BrettPhos Palladacycle

BrettPhos precatalyst

Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine-(2-(2-aminoethyl)phenyl)palladium(II) chloride

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(ii)

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-amino

CHLORO[2-(DICYCLOHEXYLPHOSPHINO)-3,6-DIMETHOXY-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL][2-(2-AMINOETHYL)PHENYL]PALLADIUM(II),MIN.98%[BRETTPHOSPALLADACYCLEGEN.1]

(SP-4-4)-[2-[2-(Amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP]palladium

Chloro[2-(dicyclohexylphosphino)-3,6-diMethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl][2-(2-aMinoethyl)phenyl]palladiuM(II) [BrettPhos Palladacycle]

[2-(2-aminoethyl)phenyl]palladium(1+)

dicyclohexyl-[3,6-dimethoxy-2-(2,4,6-triisopropylphenyl)phenyl]phosphane

BrettPhos Palladacycle Gen. 1

Chloride (2-dicyclohexylphosphino-3,6-dimethoxy-2 ', 4', 6 '- triisopropyl-1,1' - biphenyl) [2 - (2-aminoethyl phenyl)] palladium (II)

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II) / BrettPhos Pd G1

Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP]-, (SP-4-4)-

BrettPhos Pd G1

Chloro[2-(dicyclohexylphosphino)-2',4',6'-triisopropyl-3,6-dimethoxybiphenyl][2-(2-aminoethyl)phenyl]palladium(II)

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-...

BrettPhos Pd G1 / Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)

Dicyclohexyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine-(2-(2-aminoethyl)phenyl)palladium(II) chloride

chloro-(2-phenylethylamino)palladium

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2'-4'-6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)

Chloro[2-(dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II)

BrettPhos Pd G1 MTBE adduct

Chloro[2-(dicyclohexylphosphino)-2’,4’,6’-triisopropyl-3,6-dimethoxybiphenyl][2-(2-aminoethyl)phenyl]palladium(II)

Palladium, [2-[2-(amino-κN)ethyl]phenyl-κC]chloro[dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP]-, (SP-4-4)-

1148148-01-9

C43H63ClNO2PPd

C48H74ClNO3PPd

Buchwald Ligands&Precatalysts

Buchwald Precatalysts Series