t-BuBrettPhos Palladacycle Gen. 3
Reaction- Product Name
- t-BuBrettPhos Palladacycle Gen. 3
- CAS No.
- 1536473-72-9
- Chemical Name
- t-BuBrettPhos Palladacycle Gen. 3
- Synonyms
- P](methane;N)[1,1’-(Amino-κtbuttphos Pd G3;-biphenyl]-2-yl-κC][[3,6-dimethoxy-2’-tris(1-methylethyl)[1,1’t-BuBrettPhos Palladacycle Gen. 3;t-butylBrettPhos Palladacycle Gen. 3;t-BuBrettPhos Palladacycle Gen. 3 ISO 9001:2015 REACH
- CBNumber
- CB33052898
- Molecular Formula
- C44H63NO5PPdS-
- Formula Weight
- 855.433481
- MOL File
- 1536473-72-9.mol
t-BuBrettPhos Palladacycle Gen. 3 Property
- Melting point:
- 119-131°C
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- color
- brown-green
- InChI
- InChI=1S/C31H49O2P.C12H10N.CH4O3S.Pd/c1-19(2)22-17-23(20(3)4)27(24(18-22)21(5)6)28-25(32-13)15-16-26(33-14)29(28)34(30(7,8)9)31(10,11)12;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h15-21H,1-14H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;-1;;
- InChIKey
- VKLHIPFGYVFUGT-UHFFFAOYSA-N
- SMILES
- [Pd].S(C([H])([H])[H])(=O)(=O)O[H].P(C1=C(C([H])=C([H])C(=C1C1C(=C([H])C(C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C=1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])OC([H])([H])[H])OC([H])([H])[H])(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H].N([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=[C-]1
- CAS DataBase Reference
- 1536473-72-9
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 745979
- Product name
- tBuBrettPhos Pd G3
- Purity
- 96%
- Packaging
- 100MG
- Price
- $81.6
- Updated
- 2024/03/01
- Product number
- 745979
- Product name
- tBuBrettPhos Pd G3
- Purity
- 96%
- Packaging
- 500MG
- Price
- $147
- Updated
- 2024/03/01
- Product number
- 745979
- Product name
- tBuBrettPhos Pd G3
- Purity
- 96%
- Packaging
- 1G
- Price
- $341
- Updated
- 2024/03/01
- Product number
- 928313
- Product name
- tBuBrettPhos Pd G3 ChemBeads
- Packaging
- 1G
- Price
- $287
- Updated
- 2024/03/01
- Product number
- 745979
- Product name
- tBuBrettPhos Pd G3
- Purity
- 96%
- Packaging
- 2G
- Price
- $666
- Updated
- 2024/03/01
t-BuBrettPhos Palladacycle Gen. 3 Chemical Properties,Usage,Production
Reaction
- Palladium catalyst used for the arylation of primary amides.
- Palladium catalyst used for the synthesis of N-aryl carbamates.
- Palladium catalyst used for the N-monoarylation of amidines.
- Palladium catalyst used for the cross-coupling of aryl chlorides and triflates with sodium cyanate – a practical synthesis of unsymmetrical ureas.
- Palladium catalyst used in the synthesis of imidazo[4,5-b]pyridines and imidazo[4,5]pyrazines through amidation of 2-chloro-3-amino-heterocycles.
- Palladium catalyst used in the N-arylation of 2-aminothiazoles
- Palladium catalyst used in the synthesis of diarylethers under mild conditions.
- Palladium catalyst used in the hydroxylation of aryl and heteroaryl halides.
Uses
tBuBrettPhos Pd G3 has been used as a precatalyst for the N-arylation of amino acid esters with aryl triflates under mild reaction conditions and minimal racemization of the amino acid ester. It may also be used to catalyze the conversion of aryl halides to phenols in the presence of benzaldoxime as a hydroxide surrogate.
General Description
tBuBrettPhos Pd G3 is a third generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. It is air-, moisture-, and thermally-stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
t-BuBrettPhos Palladacycle Gen. 3 Preparation Products And Raw materials
Raw materials
Preparation Products
t-BuBrettPhos Palladacycle Gen. 3 Suppliers
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View Lastest Price from t-BuBrettPhos Palladacycle Gen. 3 manufacturers
- Product
- Methanesulfonato(2-di-t-butylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / t-BuBrettPhos Pd G3 1536473-72-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 50KG
- Release date
- 2020-11-26
- Product
- t-BuBrettPhos Palladacycle Gen. 3 1536473-72-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- Min98%HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-09