Reaction
ChemicalBook > CAS DataBase List > t-BuBrettPhos Palladacycle Gen. 3

t-BuBrettPhos Palladacycle Gen. 3

Reaction
Product Name
t-BuBrettPhos Palladacycle Gen. 3
CAS No.
1536473-72-9
Chemical Name
t-BuBrettPhos Palladacycle Gen. 3
Synonyms
P](methane;N)[1,1’-(Amino-κtbuttphos Pd G3;-biphenyl]-2-yl-κC][[3,6-dimethoxy-2’-tris(1-methylethyl)[1,1’t-BuBrettPhos Palladacycle Gen. 3;t-butylBrettPhos Palladacycle Gen. 3;t-BuBrettPhos Palladacycle Gen. 3 ISO 9001:2015 REACH
CBNumber
CB33052898
Molecular Formula
C44H63NO5PPdS-
Formula Weight
855.433481
MOL File
1536473-72-9.mol
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t-BuBrettPhos Palladacycle Gen. 3 Property

Melting point:
119-131°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
color 
brown-green
InChI
InChI=1S/C31H49O2P.C12H10N.CH4O3S.Pd/c1-19(2)22-17-23(20(3)4)27(24(18-22)21(5)6)28-25(32-13)15-16-26(33-14)29(28)34(30(7,8)9)31(10,11)12;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h15-21H,1-14H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;-1;;
InChIKey
VKLHIPFGYVFUGT-UHFFFAOYSA-N
SMILES
[Pd].S(C([H])([H])[H])(=O)(=O)O[H].P(C1=C(C([H])=C([H])C(=C1C1C(=C([H])C(C([H])(C([H])([H])[H])C([H])([H])[H])=C([H])C=1C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C([H])([H])[H])C([H])([H])[H])OC([H])([H])[H])OC([H])([H])[H])(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H].N([H])([H])C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([H])C([H])=[C-]1
CAS DataBase Reference
1536473-72-9
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
745979
Product name
tBuBrettPhos Pd G3
Purity
96%
Packaging
100MG
Price
$81.6
Updated
2024/03/01
Sigma-Aldrich
Product number
745979
Product name
tBuBrettPhos Pd G3
Purity
96%
Packaging
500MG
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
745979
Product name
tBuBrettPhos Pd G3
Purity
96%
Packaging
1G
Price
$341
Updated
2024/03/01
Sigma-Aldrich
Product number
928313
Product name
tBuBrettPhos Pd G3 ChemBeads
Packaging
1G
Price
$287
Updated
2024/03/01
Sigma-Aldrich
Product number
745979
Product name
tBuBrettPhos Pd G3
Purity
96%
Packaging
2G
Price
$666
Updated
2024/03/01
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t-BuBrettPhos Palladacycle Gen. 3 Chemical Properties,Usage,Production

Reaction

  1. Palladium catalyst used for the arylation of primary amides.
  2. Palladium catalyst used for the synthesis of N-aryl carbamates.
  3. Palladium catalyst used for the N-monoarylation of amidines.
  4. Palladium catalyst used for the cross-coupling of aryl chlorides and triflates with sodium cyanate – a practical synthesis of unsymmetrical ureas.
  5. Palladium catalyst used in the synthesis of imidazo[4,5-b]pyridines and imidazo[4,5]pyrazines through amidation of 2-chloro-3-amino-heterocycles.
  6. Palladium catalyst used in the N-arylation of 2-aminothiazoles
  7. Palladium catalyst used in the synthesis of diarylethers under mild conditions.
  8. Palladium catalyst used in the hydroxylation of aryl and heteroaryl halides.

Uses

tBuBrettPhos Pd G3 has been used as a precatalyst for the N-arylation of amino acid esters with aryl triflates under mild reaction conditions and minimal racemization of the amino acid ester. It may also be used to catalyze the conversion of aryl halides to phenols in the presence of benzaldoxime as a hydroxide surrogate.

General Description

tBuBrettPhos Pd G3 is a third generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. It is air-, moisture-, and thermally-stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.

t-BuBrettPhos Palladacycle Gen. 3 Preparation Products And Raw materials

Raw materials

Preparation Products

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t-BuBrettPhos Palladacycle Gen. 3 Suppliers

xinxiang runyu material co.,Ltd
Tel
15690792173
Fax
0373-7759608
Email
sales@runvmat.com
Country
China
ProdList
111
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58
Wu Han Lbpchem Chemical Co., Ltd.
Tel
02763499399 13797220777
Email
lpbchem@163.com
Country
China
ProdList
99
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58
Hubei Metcata Co., Ltd.
Tel
027-86643599 18140660632
Email
106469325@qq.com
Country
China
ProdList
26
Advantage
58
Wuhan phosphine biologic Pharmaceutical Co., LTD
Tel
15102702255 15102702255
Email
35729423@qq.com
Country
China
ProdList
106
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58
Zhengzhou Kingorgchem Chemical Technology Co., Ltd.gy Co., Ltd.
Tel
0371-65511006 18625597674
Email
sales@kingorgchem.com
Country
China
ProdList
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BeiJing Greenchem Technology Co.,Ltd.
Tel
131-21959385 15640741633
Fax
010-62925455
Email
chemrocking@bjgreenchem.com
Country
China
ProdList
269
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Sinocompound Catalysts Co., Ltd.
Tel
0512-67216630 18962121273
Fax
0512-56316689
Email
sales@sinocompound.com
Country
China
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Wuhan Houshuang Technology Co., Ltd
Tel
13080686708
Email
houshuangchem@163.com
Country
China
ProdList
77
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58
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
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55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
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View Lastest Price from t-BuBrettPhos Palladacycle Gen. 3 manufacturers

Wuhan LPBchem Technology Co.,Ltd
Product
Methanesulfonato(2-di-t-butylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / t-BuBrettPhos Pd G3 1536473-72-9
Price
US $0.00-0.00/g
Min. Order
1g
Purity
0.98
Supply Ability
50KG
Release date
2020-11-26
Career Henan Chemical Co
Product
t-BuBrettPhos Palladacycle Gen. 3 1536473-72-9
Price
US $1.00/g
Min. Order
1g
Purity
Min98%HPLC
Supply Ability
g/kg/ton
Release date
2020-01-09

1536473-72-9, t-BuBrettPhos Palladacycle Gen. 3Related Search:


  • Methanesulfonato 2-Di-t-butylphosphino-3,6-dimethoxy-2'-4' -6'-tri-i-propyl-1,1'-bipheny)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
  • Methanesulfonato(2-(di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), min. 98%
  • METHANESULFONATO(2-(DI-T-BUTYLPHOSPHINO)-3,6-DIMETHOXY-2',4',6'-TRI-I-PROPYL-1,1'-BIPHENYL)(2'-AMINO-1,1'-BIPHENYL-2-YL)PALLADIUM(II),DICHLOROMETHANEADDUCT,MIN.98%[T-BUBRETTPHOSPALLADACYCLEGEN.3]
  • t-BuBrettPhos Palladacycle Gen. 3
  • Methanesulfonato(2-(di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II),[t-BuBrettPhos Palladacycle Gen. 3]
  • Methanesulfonato(2-(di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), dichloromethane adduct, min. 98%[t-BuBrettPhos Palladacycle Gen.
  • Methanesulfonato[2-(di-t-butylphosphino)-3,6-dimethoxy-2’,4’,6’-tri-i-propyl-1,1’-biphenyl](2’-amino-1,1’-biphenyl-2-yl)palladium(II)
  • [2'-(amino-κN)[1,1'-biphenyl]-2-yl-κC][[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]bis(1,1-dimethyle
  • t-butylBrettPhos Palladacycle Gen. 3
  • Methanesulfonate[(2-Di-tert-butylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)-2-(2'-amino-1,1'-biphenyl)]palladium(II) tBuBrettPhos Pd G3
  • Methanesulfonato(2-di-t-butylphosphino-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) / t-BuBrettPhos Pd G3
  • 2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]bis(1,1-dimethylethyl)phosphine-κP](methanesulfonato-κO)palladium
  • -(Amino-&kappa
  • -biphenyl]-2-yl-&kappa
  • -biphenyl]-2-yl]bis(1,1-dimethylethyl)phosphine-&kappa
  • C][[3,6-dimethoxy-2&rsquo
  • N)[1,1&rsquo
  • P](methane
  • -tris(1-methylethyl)[1,1&rsquo
  • t-BuBrettPhos Palladacycle Gen. 3 ISO 9001:2015 REACH
  • 2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]bis(1,1-dimethylethyl)phosphine-κP](methanesulfonato-κO)palladium (tBuBrettPhos Pd G3)
  • Methanesulfonato(2-Di-t-butylphosphino-3,6-dimethoxy-2'-4' -6'-tri-i-propyl-1,1'-bipheny)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) (tBuBrettPhos Pd G3)
  • t-ButylXPhos Pd G4 / Methanesulfonato(2-di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-methylamino-1,1'-biphenyl-2-yl)palladium(II)
  • tbuttphos Pd G3
  • methanesulfonato 2-di-t-butylphosphino-3,6-dimethoxy-2'-4' -6'-tri-i-propyl-1,1'-bipheny)(2'-amino-1,1'-biphenyl-2-yl)palladium(ii)
  • (2-Di-tert-butylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)-2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate
  • ditert-butyl-[3,6-dimethoxy-2-(2,4,6-triisopropylphenyl)phenyl]phosphane methylsulfonyloxy-(2-phenylanilino)palladium
  • Methanesulfonato(2-(di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II)
  • Methanesulfonato(2-(di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II),[t-BuBrettPhos Palladacycle Gen. 3]
  • Methanesulfonato(2-Di-t-butylphosphino-3,6-dimethoxy-2'-4' -6'-tri-i-propyl-1,1'-bipheny)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) (tBuBrettPhos Pd G3)
  • 1536473-72-9
  • C44H62NO5PPdS
  • C31H49O2PC13H13NO3PdS
  • Buchwald Ligands&Precatalysts
  • Buchwald Precatalysts Series
  • Pd