GB4

Product Name: GB4
CAS No.: 11034-93-8
Chemical Name: GB4
Synonyms: GL4;GB4;GLOBOSIDE;GBOSE4CER;CytolipinK;GlobosideI;GLOBOSIDES;GlobosideGL4;GangliosideGL4;Globosidicacid
CBNumber: CB5283013
Molecular Formula: C56H102N2O23
Formula Weight: 0
MOL File: 11034-93-8.mol

More

Less

GB4 Property

storage temp.: −20°C
solubility: Chloroform:Methanol (2:1): Soluble; DMSO: Soluble; Methanol: Warmed
form: A solid

More

Less

Safety

WGK Germany: 3
HS Code: 29400090

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 24881
Product name: Globotetraosylceramides (porcine RBC)
Purity: ≥98%
Packaging: 5mg
Price: $578
Updated: 2024/03/01

Usbiological

Product number: 297030
Product name: Globoside
Packaging: 1mg
Price: $506
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OG06812
Product name: Globoside
Packaging: 5mg
Price: $550
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OG06812
Product name: Globoside
Packaging: 1mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: OG06812
Product name: Globoside
Packaging: 2mg
Price: $300
Updated: 2021/12/16

More

Less

GB4 Chemical Properties,Usage,Production

Description

Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, and parvovirus B19. Globotetraosylceramides increase the expression of proteins responsible for enamel deposition, including ameloblastin, amelogenin, and enamelin, in dental epithelial cells and activate the ERK and p38 MAPK signaling pathways. Levels of globotetraosylceramides are elevated in fibroblasts from patients with salt and pepper syndrome, a neurocutaneous condition characterized by intellectual disability and hyper- and hypo-pigmented skin. Globotetraosylceramides (porcine RBC) contains a mixture of globotetraosylceramides with variable fatty acyl chain lengths isolated from porcine red blood cells. [Matreya, LLC. Catalog No. 1068]

Chemical Properties

White powder

Uses

Globotetraosylceramide (porcine RBC) is a biochemical reagent.

References

[1] T YAMAKAWA N K S YOKOYAMA. Structure of main globoside of human erythrocytes.[J]. Journal of biochemistry, 1962, 52: 228-229. DOI: 10.1093/oxfordjournals.jbchem.a127603
[2] J. MüTHING. Shiga toxins, glycosphingolipid diversity, and endothelial cell injury[J]. Thrombosis and haemostasis, 2009, 101 1: 252-264. DOI: 10.1160/th08-05-0317
[3] YUKO MATSUSHIMA-HIBIYA. Identification of glycosphingolipid receptors for pierisin-1, a guanine-specific ADP-ribosylating toxin from the cabbage butterfly.[J]. The Journal of Biological Chemistry, 2003, 278 11: 9972-9978. DOI: 10.1074/jbc.m212114200
[4] WAQAS NASIR . Parvovirus B19 VLP recognizes globoside in supported lipid bilayers[J]. Virology, 2014, 456: Pages 364-369. DOI: 10.1016/j.virol.2014.04.004
[5] TAKASHI NAKAMURA. Globoside accelerates the differentiation of dental epithelial cells into ameloblasts[J]. International Journal of Oral Science, 2016, 8 4: 205-212. DOI: 10.1038/ijos.2016.35
[6] LUIGI BOCCUTO. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation.[J]. Human molecular genetics, 2014, 23 2: 418-433. DOI: 10.1093/hmg/ddt434

GB4 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GB4 Suppliers

China 22 Japan 1 Sweden 1 Switzerland 1 United Kingdom 2 United States 9 Global 36

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Yichang Zhongyitai Trading Co., Ltd.

Tel: 0717-6449896 13886658719
Fax: 0717-6558598
Email: root@zhongyitai.com
Country: China
ProdList: 1978
Advantage: 58

Alfa Chemistry

Tel: 1-516-6625404
Fax: 1-516-927-0118
Email: support@alfa-chemistry.com
Country: United States
ProdList: 9171
Advantage: 60

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

BOC Sciences

Tel: 16314854226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 9713
Advantage: 58

11034-93-8, GB4Related Search:

N-BUTYLISOCYANIDE METHYL ISOCYANOACETATE TERT-BUTYL ISOCYANIDE Tosylmethyl isocyanide Benzyl isocyanide Ferric acetylacetonate SALCOMINE Aluminum acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ethyl isocyanoacetate Cupric acetylacetonate PHENYLSELENOL DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tris(2,4-pentanedionato)chroMiuM(III) COBALT(II) ACETYLACETONATE PONCEAU 4 GB

Ceramide,1-O-[O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1-)3)-O-α-D-galactopyranosyl-(1-)4)-O-β-D-galactopyranosyl-(1-)4)-β-D-glucopyranosyl]-

CytolipinK

GangliosideGL4

globosidefromhumanerythrocytes

GlobosideGL4

GlobosideI

Globosidicacid

GBOSE4CER

GB4

GL4

GLOBOSIDE

GLOBOSIDES

GLOBOTETRAHEXOSYL-CERAMIDE

GLOBOTETRAOSYLCERAMIDE

GLOBOTETRAOSYL CREAMIDE

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)dodecanamide

Tetrahexosylceramide (d18:1/12:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexadecanamide

Tetrahexosylceramide (d18:1/16:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)octadecanamide

Tetrahexosylceramide (d18:1/18:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)icosanamide

Tetrahexosylceramide (d18:1/20:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)docosanamide

Tetrahexosylceramide (d18:1/22:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)tetracosanamide

Tetrahexosylceramide (d18:1/24:0)

(Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)tetracos-15-enamide

Tetrahexosylceramide (d18:1/24:1(15Z))

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)pentacosanamide

Tetrahexosylceramide (d18:1/25:0)

N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexacosanamide

Tetrahexosylceramide (d18:1/26:0)

(Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)hexacos-17-enamide

Tetrahexosylceramide (d18:1/26:1(17Z))

(Z)-N-((2S,3R,E)-1-((2R,3R,4R,5S,6R)-5-((2S,3R,4R,5R,6R)-5-((2R,3R,4S,5S,6R)-4-((2S,3R,4R,5R,6R)-3-ethanamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-3-hydroxyoctadec-4-en-2-yl)octadec-9-enamide

Tetrahexosylceramide (d18:1/9Z-18:1)

GLOBOTETRAOSYLCERAMIDE, FROM PORCINE ERYTHROCYTE

(Z)-1-O-[4-O-[4-O-[3-O-(2-Deoxy-2-acetylamino-β-D-glucopyranosyl)-α-D-galactopyranosyl]-β-D-galactopyranosyl]-β-D-glucopyranosyl]-N-(1-oxotetracosyl)-4-sphingenine

Globosides (huMan)

Globosylceramide

N-acetyl-beta-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide

Globotetraosylceramides (porcine RBC)

Globotetraosylceramide (porcine RBC)

11034-93-8

Biochemicals and Reagents

BioChemical

Glycolipids

Complex Lipids

Lipids

Others