ChemicalBook > CAS DataBase List > ML-180

ML-180

Product Name
ML-180
CAS No.
863588-32-3
Chemical Name
ML-180
Synonyms
ML-180;SR1848;ML-180 (SR1848);SR1848 >=98% (HPLC);6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-
CBNumber
CB53152684
Molecular Formula
C20H25ClN4O2
Formula Weight
388.89
MOL File
863588-32-3.mol
More
Less

ML-180 Property

Density 
1.312±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 10 mg/ml
form 
A crystalline solid
pka
9.37±0.40(Predicted)
color 
Off-white to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
5mg
Price
$108
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
25mg
Price
$345
Updated
2024/03/01
AK Scientific
Product number
SYN5289
Product name
ML180
Packaging
10mg
Price
$160
Updated
2021/12/16
More
Less

ML-180 Chemical Properties,Usage,Production

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

Definition

ChEBI: 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione is a member of piperazines.

ML-180 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ML-180 Suppliers

Jingmo (Xiamen) Biotechnology Co., Ltd
Tel
13621943973; 13621943973
Email
sales@jamxmpharmatech.com
Country
China
ProdList
1111
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4674
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4566
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8012
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2988
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7296
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58

863588-32-3, ML-180Related Search:


  • SR1848
  • ML-180
  • 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
  • 2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-
  • 6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione
  • SR1848 >=98% (HPLC)
  • ML-180 (SR1848)
  • 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
  • 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • ML-180,steroidogenic,SR-1848,Inhibitor,ML180,Orphan,factor-1,LRH-1,cancers,nuclear,NR5A2,NR5A1,ML 180,inhibit,homolog,liver,SR 1848,receptor,SF-1
  • 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
  • 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione
  • 863588-32-3