ChemicalBook > CAS DataBase List > ML-180

ML-180

Product Name
ML-180
CAS No.
863588-32-3
Chemical Name
ML-180
Synonyms
ML-180;SR1848;ML-180 (SR1848);SR1848 >=98% (HPLC);6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-
CBNumber
CB53152684
Molecular Formula
C20H25ClN4O2
Formula Weight
388.89
MOL File
863588-32-3.mol
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ML-180 Property

Density 
1.312±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 10 mg/ml
form 
A crystalline solid
pka
9.37±0.40(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
5mg
Price
$108
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
10mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
15181
Product name
ML-180
Purity
≥98%
Packaging
25mg
Price
$345
Updated
2024/03/01
AK Scientific
Product number
SYN5289
Product name
ML180
Packaging
10mg
Price
$160
Updated
2021/12/16
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ML-180 Chemical Properties,Usage,Production

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

Definition

ChEBI: 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2,4-dione is a member of piperazines.

ML-180 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML-180 Suppliers

China 48 United States 4 Global 52
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

863588-32-3, ML-180Related Search:

5-[(4-Nitrobenzoyl)oxy]-2-[(2-pyrimidinylthio)methyl]-4H-pyran-4-one ML-228 ML188 (Racemate) ML 18 ML-098 ML277 ML 204 ML329 ML364 VU0456810 ML188 ML418 [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone ML213 N-(3,4-difluorophenyl)-2-pyridin-4-ylquinazolin-4-amine ML-327 PTP1B-IN-2 ML264

  • SR1848
  • ML-180
  • 6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione
  • 2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-
  • 6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione
  • SR1848 >=98% (HPLC)
  • ML-180 (SR1848)
  • 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
  • 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • ML-180,steroidogenic,SR-1848,Inhibitor,ML180,Orphan,factor-1,LRH-1,cancers,nuclear,NR5A2,NR5A1,ML 180,inhibit,homolog,liver,SR 1848,receptor,SF-1
  • 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-1H-pyrimidine-2，4-dione
  • 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione
  • 863588-32-3