Etelcalcetide

Product Name: Etelcalcetide
CAS No.: 1262780-97-1
Chemical Name: Etelcalcetide
Synonyms: Parsavib;Etelcalcetide;AMG-416 (Velcalcetide);D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine;S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine
CBNumber: CB53154325
Molecular Formula: C38H73N21O10S2
Formula Weight: 1048.25
MOL File: 1262780-97-1.mol

More

Less

Etelcalcetide Property

Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 2.01±0.10(Predicted)
Sequence: H-Cys(1)-OH,Ac-D-Cys(1)-D-Ala-D-Arg-D-Arg-D-Arg-D-Ala-D-Arg-NH2(Disulfide bridge Cys1-(D-Cys1))/C(1),Ac-（D-C（1）-（D-A）-（D-R）-（D-R）-（D-R）-（D-A）-（D-R）-NH2(Disulfide bridge Cys1-(D-Cys1))
InChIKey: HQGWMVNIZKNABK-TZUZSESWNA-N

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0030931
Product name: Etelcalcetide
Packaging: 1mg
Price: $55
Updated: 2021/12/16

ChemScene

Product number: CS-0030931
Product name: Etelcalcetide
Packaging: 5mg
Price: $138
Updated: 2021/12/16

ChemScene

Product number: CS-0030931
Product name: Etelcalcetide
Packaging: 10mg
Price: $260
Updated: 2021/12/16

ChemScene

Product number: CS-0030931
Product name: Etelcalcetide
Packaging: 25mg
Price: $520
Updated: 2021/12/16

More

Less

Etelcalcetide Chemical Properties,Usage,Production

Uses

N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl- D-Argininamide-L-cysteine Disulfide is a useful research chemical used in the treatment of chronic kidney disease-??mineral and bone disorder.

Definition

ChEBI: Etelcalcetide is an oligopeptide.

Mechanism of action

Etelcalcetide is a calcimimetic agent that allosterically modulates the calcium-sensing receptor (CaSR). Etelcalcetide binds to the CaSR and enhances activation of the receptor by extracellular calcium. Activation of the CaSR on parathyroid chief cells decreases PTH secretion.

Clinical Use

Synthetic peptide calcimimetic agent:
Treatment of secondary hyperparathyroidism in patients on haemodialysis

Drug interactions

Potentially hazardous interactions with other drugs
Avoid with cinacalcet.

Metabolism

Etelcalcetide is biotransformed in blood by reversible disulphide exchange with endogenous thiols to predominantly form conjugate with serum albumin

Etelcalcetide Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Etelcalcetide Suppliers

China 93 India 1 United Kingdom 1 United States 4 USA 1 Global 100

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Hangzhou Peptide Biochem Co.,Ltd

Tel: 0571-89197072; 18668118770
Fax: 0571-89197072
Email: linda@peptide-china.com
Country: China
ProdList: 235
Advantage: 56

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 9126
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12476
Advantage: 58

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

More

Less

View Lastest Price from Etelcalcetide manufacturers

Chongqing Soarwin Technology Co., Ltd

Product: Etelcalcetide 1262780-97-1
Price: US $0.00-0.00/Box
Min. Order: 1Box
Purity: 99.99%
Supply Ability: 10 Boxes
Release date: 2025-06-10

Zibo Hangyu Biotechnology Development Co., Ltd

Product: Etelcalcetide 1262780-97-1
Price: US $75.00-750.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-30

Zhuozhou Wenxi import and Export Co., Ltd

Product: Etelcalcetide 1262780-97-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

1262780-97-1, EtelcalcetideRelated Search:

Irofulven Dermorphin Acetyl Hexapeptide-1 GLUCAGON (1-37) (PORCINE) N2-Acetyl-L-lysyl-L-alpha-aspartyl-L-valyl-L-tyrosine Melanotan 1 Palmitoyl Hexapeptide-12 Pexiganan omiganan pentahydrochloride Acetyl Decapeptide-3 PAL-KTTKS Eptifibatide Sincalide Abaloparatide Ganirelix Acetate Thyrotropin-releasing hormone VAPREOTIDE PASIREOTIDE

Etelcalcetide

D-Argininamide, N-acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-, disulfide with L-cysteine

AMG-416 (Velcalcetide)

Parsavib

S-(((S)-2-Acetamido-3-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-(((R)-1-amino-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-5-guanidino-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-3-oxopropyl)thio)-L-cysteine

1262780-97-1

C38H73N21O10S2