ChemicalBook > CAS DataBase List > CP671305

CP671305

Product Name
CP671305
CAS No.
445295-04-5
Chemical Name
CP671305
Synonyms
CS-2886;CP671305;UNII-9LH034R9R9;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
CBNumber
CB53175535
Molecular Formula
C23H19FN2O7
Formula Weight
454.4
MOL File
445295-04-5.mol
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CP671305 Property

storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
5mg
Price
$193
Updated
2024/03/01
ChemScene
Product number
CS-6774
Product name
CP671305
Purity
99.95%
Packaging
25mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
BC161230
Product name
CP 671305
Packaging
2mg
Price
$250
Updated
2021/12/16
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CP671305 Chemical Properties,Usage,Production

Description

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.

CP671305 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP671305 Suppliers

China 32 United Kingdom 1 United States 6 Global 39
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
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China
ProdList
4512
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55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
1009
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55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
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62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7267
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58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
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China
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1990
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58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
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58
Wuxi Donghe Pharmaceutical Technology Co., Ltd.
Tel
63313187 15358055255
Fax
QQ：63313187
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63313187@qq.com
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China
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1988
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
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China
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11217
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Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
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5132
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58
Chunchuang (Wuhan) Technology Co., Ltd
Tel
15342225168
Email
yutianchun2007@126.com
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China
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10002
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58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
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4494
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58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
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Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ：2860768577
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sales@hasunny.com
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2380
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InvivoChem
Tel
13549236410
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sales@invivochem.cn
Country
China
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Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
Tel
17771424646
Email
shoubull@126.com
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China
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969
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TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
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24647
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58
Henan Alpha Chemical Co., Ltd.
Tel
0371-55013243 15324716602
Email
2853979810@qq.com
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China
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10018
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58
Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
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sales@tybiochem.com
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China
ProdList
6813
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Shanghai Jieshikai Biotechnology Co. , Ltd.
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021-57520305 15221441005
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lihua@jskchem.com
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China
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https://hanhongsci.com/
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021-54306202 18917919676
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info@hanhongsci.com
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China
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29977
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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+86-18521732826
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market@aladdin-e.com
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China
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48461
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xinguokeji
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13120711461
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363372932@qq.com
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China
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496
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Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.
Tel
025-66061636 18013972705
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qqyang@aikonchem.com
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China
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10238
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Shanghai Hansi Chemical Industry Co., Ltd.
Tel
17717618050
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zllg@gh-reagent.com
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China
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10422
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Tel
4008-099-669
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23419001name@qq.com
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CHINA
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70071
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ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
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ivan@atkchemical.com
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China
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32957
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Chemia Biotechnology（Shanghai） Co., Ltd
Tel
+8613816753574
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info@chemia-pharm.com
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CHINA
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311
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Guangzhou Weijia Technology Co., Ltd.
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--
Fax
--
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WHIGA22@126.COM
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CHINA
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6748
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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--
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6650
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Shanghai Qiming Biological Technology Co., Ltd.
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Shanghai Jingke Chemical Technology Co., Ltd.
Tel
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Email
jingkehuaxue@163.com
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6972
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445295-04-5, CP671305Related Search:

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE 4-Chloro-N,N-diethylbenzaMide, 97% 4-Chloro-N,N-di-n-propylbenzaMide, 97% TIMTEC-BB SBB006342 NSC781406 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 NSC 42834

  • CP671305
  • CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5
  • UNII-9LH034R9R9
  • CS-2886
  • Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
  • (R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid
  • CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
  • 445295-04-5
  • API