ChemicalBook > CAS DataBase List > CP671305

CP671305

Product Name
CP671305
CAS No.
445295-04-5
Chemical Name
CP671305
Synonyms
CS-2886;CP671305;UNII-9LH034R9R9;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
CBNumber
CB53175535
Molecular Formula
C23H19FN2O7
Formula Weight
454.4
MOL File
445295-04-5.mol
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CP671305 Property

storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
5mg
Price
$193
Updated
2024/03/01
ChemScene
Product number
CS-6774
Product name
CP671305
Purity
99.95%
Packaging
25mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
BC161230
Product name
CP 671305
Packaging
2mg
Price
$250
Updated
2021/12/16
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CP671305 Chemical Properties,Usage,Production

Description

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.

CP671305 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP671305 Suppliers

China 31 United Kingdom 1 United States 5 Global 37
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
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+86-21-52996696
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China
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4153
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Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
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China
ProdList
991
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55
ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
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QQ:2853530913
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2853530910@QQ.com
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China
ProdList
8011
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Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
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QQ:1369748377
Email
sales@rechemscience.com
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China
ProdList
2989
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58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 15618227136
Fax
21-5161 9052
Email
info@SuperLan-chem.com
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China
ProdList
9747
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58
Taizhou Crene Biotechnology Co. Ltd.
Tel
0576-88813233 13396860566
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sales@pharm-intermediates.com
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China
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2013
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58
DC Chemicals
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021-58447131 13564518121
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sales@dcchemicals.com
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China
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9414
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Wuxi Donghe Pharmaceutical Technology Co., Ltd.
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63313187 15358055255
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QQ：63313187
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63313187@qq.com
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China
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1977
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767
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QQ 3610331285
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sales@chemegen.com
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China
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Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
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China
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Chunchuang (Wuhan) Technology Co., Ltd
Tel
15342225168
Email
yutianchun2007@126.com
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China
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10003
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Abmole Bioscience Inc.
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021-50967598 02150967598
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sales@abmole.cn
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China
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4495
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Bide Pharmatech Ltd.
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400-1647117 15221909166
Email
product02@bidepharm.com
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China
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Kaifeng Mingren Pharmaceutical Co.,LTD
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0371-65741762
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QQ：2860768577
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sales@hasunny.com
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InvivoChem
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13549236410
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sales@invivochem.cn
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China
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Wuhan Shanhai Zhihe Biotechnology Co., Ltd.
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17771424646
Email
shoubull@126.com
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China
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Shanghai Hansi Chemical Industry Co., Ltd.
Tel
17717618050
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zllg@gh-reagent.com
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China
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10424
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58
TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Henan Alpha Chemical Co., Ltd.
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0371-55013243 15324716602
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2853979810@qq.com
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China
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Nanjing Tengyi Biotechnology Co., Ltd
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025-58851786 17714337195
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sales@tybiochem.com
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China
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5021
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Shanghai Jieshikai Biotechnology Co. , Ltd.
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021-57520305 13764600721
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wangkang@jskchem.com
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China
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49036
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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China
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8740
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https://hanhongsci.com/
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021-54306202 18917919676
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China
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29989
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Wuhan Acumen Bio-Technology Co.,ltd
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027-027-16602739303 16602739303
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China
ProdList
2887
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
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48467
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ATK CHEMICAL COMPANY LIMITED
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ivan@atkchemical.com
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Chemia Biotechnology（Shanghai） Co., Ltd
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info@chemia-pharm.com
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CHINA
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311
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Guangzhou Weijia Technology Co., Ltd.
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--
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WHIGA22@126.COM
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Shanghai Hao Zhun Biological Technology Co., Ltd.
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Shanghai Jingke Chemical Technology Co., Ltd.
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--
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jingkehuaxue@163.com
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CHINA
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6974
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58

445295-04-5, CP671305Related Search:

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE 4-Chloro-N,N-diethylbenzaMide, 97% 4-Chloro-N,N-di-n-propylbenzaMide, 97% TIMTEC-BB SBB006342 NSC781406 2,4-Thiazolidinedione,5-[(4-hydroxy-3-methoxyphenyl)methylene]- 4-Chloro-N,N-diisopropylbenzamide Pifithrin-μ 2-Pyridinecarbothioamide, N-2-pyridinyl- 1,3-Bis(4-aminophenyl)urea 5-(4-iodobenzylidene)rhodanine S3I-201 NSC228155 NSC632839hydrochloride NSC23005 Sodium HAMNO NSC 247030 NSC 42834

  • CP671305
  • CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5
  • UNII-9LH034R9R9
  • CS-2886
  • Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
  • (R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid
  • CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
  • 445295-04-5
  • API