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CP671305

Product Name
CP671305
CAS No.
445295-04-5
Chemical Name
CP671305
Synonyms
CS-2886;CP671305;UNII-9LH034R9R9;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
CBNumber
CB53175535
Molecular Formula
C23H19FN2O7
Formula Weight
454.4
MOL File
445295-04-5.mol
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CP671305 Property

storage temp. 
Store at -20°C
solubility 
DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
10mg
Price
$341
Updated
2024/03/01
Cayman Chemical
Product number
26743
Product name
CP 671,305
Packaging
5mg
Price
$193
Updated
2024/03/01
ChemScene
Product number
CS-6774
Product name
CP671305
Purity
99.95%
Packaging
25mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
BC161230
Product name
CP 671305
Packaging
2mg
Price
$250
Updated
2021/12/16
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CP671305 Chemical Properties,Usage,Production

Description

CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.

CP671305 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP671305 Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4512
Advantage
55
Shanghaizehan biopharma technology co., Ltd.
Tel
021-61350663 13052117465
Fax
021-61350662
Email
sales@zehanbiopharma.com
Country
China
ProdList
1009
Advantage
55
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2992
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7266
Advantage
58
Taizhou Crene Biotechnology Co. Ltd.
Tel
+86-0576-88813233 +86-13396860566
Email
sales@pharm-intermediates.com
Country
China
ProdList
1990
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58

445295-04-5, CP671305Related Search:


  • CP671305
  • CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5
  • UNII-9LH034R9R9
  • CS-2886
  • Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
  • (R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid
  • CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
  • 445295-04-5
  • API