ChemicalBook > CAS DataBase List > 2'-Fluoroacetophenone

2'-Fluoroacetophenone

Product Name
2'-Fluoroacetophenone
CAS No.
445-27-2
Chemical Name
2'-Fluoroacetophenone
Synonyms
2-FLUOROACETOPHENONE;1-(2-FLUOROPHENYL)ETHANONE;2'-Fluoro;Vonoprazan-041;uoroacetophenone;2-Fluoracetophenon;TAK438 Impurity 97;Fluoroacetophenone1;O-FLUOROACETOPHENONE;2'-FLUOROACETOPHENONE
CBNumber
CB5330344
Molecular Formula
C8H7FO
Formula Weight
138.14
MOL File
445-27-2.mol
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2'-Fluoroacetophenone Property

Melting point:
26-27C
Boiling point:
187-189 °C(lit.)
Density 
1.137 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.507(lit.)
Flash point:
143 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Soluble in Acetone, Chloroform, Dichloromethane, Ethanol, Ethyl Acetate and Methanol.
form 
Liquid
Specific Gravity
1.121
color 
Clear colorless to yellow
BRN 
2041344
InChIKey
QMATYTFXDIWACW-UHFFFAOYSA-N
CAS DataBase Reference
445-27-2(CAS DataBase Reference)
NIST Chemistry Reference
o-Fluoroacetophenone(445-27-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-37
RIDADR 
1993
WGK Germany 
3
HazardClass 
IRRITANT
PackingGroup 
III
HS Code 
29147090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
183717
Product name
2′-Fluoroacetophenone
Purity
97%
Packaging
5g
Price
$124
Updated
2023/06/20
TCI Chemical
Product number
F0364
Product name
2'-Fluoroacetophenone
Purity
>97.0%(GC)
Packaging
5g
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
F0364
Product name
2'-Fluoroacetophenone
Purity
>97.0%(GC)
Packaging
25g
Price
$25
Updated
2024/03/01
Alfa Aesar
Product number
A15128
Product name
2'-Fluoroacetophenone, 97%
Packaging
5g
Price
$36.65
Updated
2024/03/01
Alfa Aesar
Product number
A15128
Product name
2'-Fluoroacetophenone, 97%
Packaging
25g
Price
$115.65
Updated
2024/03/01
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2'-Fluoroacetophenone Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow or light green

Uses

2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 6179, 1990 DOI: 10.1016/S0040-4039(00)97018-7

General Description

The enantioselective reduction of 2′-fluoroacetophenone has been investigated.

2'-Fluoroacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-Fluoroacetophenone Suppliers

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Ningbo Zhenlei Chemical Co.,ltd.
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View Lastest Price from 2'-Fluoroacetophenone manufacturers

Henan Fengda Chemical Co., Ltd
Product
2'-Fluoroacetophenone 445-27-2
Price
US $100.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-24
Hebei Yanxi Chemical Co., Ltd.
Product
2'-Fluoroacetophenone 445-27-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-09-18
Hangzhou ICH Biofarm Co., Ltd
Product
2'-Fluoroacetophenone 445-27-2
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
99.0%min
Supply Ability
200kg
Release date
2023-06-09

445-27-2, 2'-FluoroacetophenoneRelated Search:

L-PICEIN 2-Fluorophenylacetic acid 2',4'-Dichloroacetophenone 2-Fluorobenzyl cyanide 4'-Hydroxyacetophenone 3-Aminoacetophenone Acetophenone 2-Bromoacetophenone 4'-Bromoacetophenone 4'-(Trifluoromethyl)acetophenone 2'-Hydroxyacetophenone 3-Nitroacetophenone 4-Nitroacetophenone 2-BROMO-2'-FLUOROACETOPHENONE ω-Bromo-4-fluoroacetophenone, 4-Fluorophenacyl bromide,2-Bromo-p-fluoroacetophenone,2'-BROMO-4-FLUOROACETOPHENONE,2-BROMO-4'-FLUOROACETOPHENONE 2-Fluoropropiophenone 2'-Bromoacetophenone 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde

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  • 2-FLUOROACETOPHENONE
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  • 2'-Flouoroacetophenone
  • 2-Acetylfluorobenzene
  • 2-Fluoroacetophenone,97%
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  • 2'-Fluoroacetophenone 97%
  • Vonoprazan Fumarate Impurity 56
  • Vonoprazan Impurity 31
  • uoroacetophenone
  • 2-Fluoracetophenon
  • 2'-Fluoroacetophenone&gt
  • TAK438 Impurity 97
  • Vonoprazan-041
  • Vonoprazan Impurity 97
  • 1-(2-Fluorophenyl)ethan-1-one (Vonoprazan Impurity）
  • Methyl 2-fluorophenyl ketone
  • 2'-Fluoroacetophenone
  • 445-27-2
  • Carbonyl Compounds
  • C7 to C8
  • Building Blocks
  • Ketones
  • Organic Building Blocks
  • Aromatic Acetophenones & Derivatives (substituted)
  • Fluorobenzene
  • ketone
  • Adehydes, Acetals & Ketones
  • Fluorine Compounds
  • C7 to C8
  • Acetophenone Series
  • Aryl Fluorinated Building Blocks
  • Building Blocks
  • C7 to C8
  • C8-C12
  • Carbonyl Compounds
  • Chemical Synthesis
  • Fluorinated Building Blocks
  • Organic Building Blocks
  • Organic Fluorinated Building Blocks
  • Other Fluorinated Organic Building Blocks
  • Carbonyl Compounds
  • Ketones
  • 11
  • 445-27-2
  • pharmaceutical