Alverine

Product Name: Alverine
CAS No.: 150-59-4
Chemical Name: Alverine
Synonyms: SESTRON;ALVERINE;PROFENIL;dipropylin;sestronbase;DIPROPYLINE;Seston base;phenpropamine;Alverine base;PHENOPROPAMINE
CBNumber: CB5333673
Molecular Formula: C20H27N
Formula Weight: 281.44
MOL File: 150-59-4.mol

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Alverine Property

Melting point:: <25 °C
Boiling point:: bp0.3 165-168°; bp13 210-215°
Density: 0.973±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
pka: 9.51±0.50(Predicted)
NIST Chemistry Reference: Benzenepropanamine, n-ethyl-n-(3-phenylpropyl)-(150-59-4)

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Safety

Hazardous Substances Data: 150-59-4(Hazardous Substances Data)
Toxicity: women,TDLo,oral,126mg/kg/5W-I (126mg/kg),BEHAVIORAL: ANOREXIA (HUMANLIVER: LIVER FUNCTION TESTS IMPAIREDLIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE",Journal of Hepathology. Vol. 27, Pg. 399, 1997.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R278459
Product name: N-ETHYL-3,3''-DIPHENYLDIPROPYLAMINE
Purity: AldrichCPR
Packaging: 50MG
Price: $106
Updated: 2023/06/20

Matrix Scientific

Product number: 098071
Product name: Alverine
Purity: 95+%
Packaging: 250mg
Price: $341
Updated: 2021/12/16

AK Scientific

Product number: V0596
Product name: Alverine
Packaging: 250mg
Price: $510
Updated: 2021/12/16

Matrix Scientific

Product number: 098071
Product name: Alverine
Purity: 95+%
Packaging: 1g
Price: $756
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0005666
Product name: 4-HYDROXY-1-OXO-ALVERINE
Purity: 95.00%
Packaging: 1G
Price: $780.15
Updated: 2021/12/16

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Alverine Chemical Properties,Usage,Production

Originator

Alverine citrate,Kemikos

Uses

Anticholinergic.

Definition

ChEBI: A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel synd ome.

Manufacturing Process

2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
In practice it is usually used as citrate.

Therapeutic Function

Anticholinergic, Spasmolytic

Alverine Preparation Products And Raw materials

Raw materials

Preparation Products

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Alverine Suppliers

China 25 Germany 3 India 4 Norway 1 Slovakia 1 United Kingdom 1 United States 9 USA 1 Global 45

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View Lastest Price from Alverine manufacturers

Career Henan Chemical Co

Product: alverine 150-59-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPLC
Supply Ability: 10 tons/month
Release date: 2020-01-09

150-59-4, AlverineRelated Search:

3-Amino-3-phenylpropionic acid Trinexapac-ethyl 2-Ethoxyethanol Ethyl propionate ISOXADIFEN-ETHYL Ethyl acetate Ethylparaben Ethyl formate Ethanol Diphenoxylate Loperamide hydrochloride Savoxepin Alverine base or citrate,alverine dihydrogen citrate,ALVERINE CITRATE,ALVERINE CITRATE SALT DIPHENOXYLATE HYDROCHLORIDE phenoperidine (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Diethyl ether D/L-AMPHETAMINE HYDROCHLORIDE

n-ethyl-n-(3-phenylpropyl)benzenepropanamine

SESTRON

Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-

di(phenylpropyl)ethylamine

dipropylin

n-ethyl-3,3’-diphenyl-dipropylamin

n-ethyl-3,3’-diphenyldipropylamine

N-Ethyl-3,3'-diphenyldipropylamine

N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine

n-ethyl-n-(3-phenylpropyl)-benzenepropanamin

phenpropamine

sestronbase

ALVERINE

DIPROPYLINE

BIS(GAMMA-PHENYLPROPYL)ETHYLAMINE

Bis(gamma-phenylpropyl)ethylamine Dipropyline Phenopropamine Profenil Sestron

Alverine base

N-Ethyl-N-(3-phenylpropyl)benzenepropan-1-amine

Seston base

Alverine (free base)

PHENOPROPAMINE

PROFENIL

Alverine in isooctane

150-59-4