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Alverine

Product Name
Alverine
CAS No.
150-59-4
Chemical Name
Alverine
Synonyms
SESTRON;ALVERINE;PROFENIL;dipropylin;sestronbase;DIPROPYLINE;Seston base;phenpropamine;Alverine base;PHENOPROPAMINE
CBNumber
CB5333673
Molecular Formula
C20H27N
Formula Weight
281.44
MOL File
150-59-4.mol
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Alverine Property

Melting point:
<25 °C
Boiling point:
bp0.3 165-168°; bp13 210-215°
Density 
0.973±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
9.51±0.50(Predicted)
NIST Chemistry Reference
Benzenepropanamine, n-ethyl-n-(3-phenylpropyl)-(150-59-4)
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Safety

Hazardous Substances Data
150-59-4(Hazardous Substances Data)
Toxicity
women,TDLo,oral,126mg/kg/5W-I (126mg/kg),BEHAVIORAL: ANOREXIA (HUMANLIVER: LIVER FUNCTION TESTS IMPAIREDLIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE",Journal of Hepathology. Vol. 27, Pg. 399, 1997.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
R278459
Product name
N-ETHYL-3,3'-DIPHENYLDIPROPYLAMINE
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$113
Updated
2025/07/31
Sigma-Aldrich
Product number
R278459
Product name
N-ETHYL-3,3''-DIPHENYLDIPROPYLAMINE
Purity
AldrichCPR
Packaging
50MG
Price
$106
Updated
2023/06/20
Matrix Scientific
Product number
098071
Product name
Alverine
Purity
95+%
Packaging
250mg
Price
$341
Updated
2021/12/16
AK Scientific
Product number
V0596
Product name
Alverine
Packaging
250mg
Price
$510
Updated
2021/12/16
Matrix Scientific
Product number
098071
Product name
Alverine
Purity
95+%
Packaging
1g
Price
$756
Updated
2021/12/16
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Alverine Chemical Properties,Usage,Production

Originator

Alverine citrate,Kemikos

Uses

Anticholinergic.

Definition

ChEBI: A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel synd ome.

Manufacturing Process

2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
In practice it is usually used as citrate.

Therapeutic Function

Anticholinergic, Spasmolytic

Alverine Preparation Products And Raw materials

Raw materials

Preparation Products

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Alverine Suppliers

Shanghai HuanChuan Industry Co.,Ltd.
Tel
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China
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Aikon International Limited
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View Lastest Price from Alverine manufacturers

Career Henan Chemical Co
Product
alverine 150-59-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98% HPLC
Supply Ability
10 tons/month
Release date
2020-01-09

150-59-4, AlverineRelated Search:


  • n-ethyl-n-(3-phenylpropyl)benzenepropanamine
  • SESTRON
  • Benzenepropanamine, N-ethyl-N-(3-phenylpropyl)-
  • di(phenylpropyl)ethylamine
  • dipropylin
  • n-ethyl-3,3’-diphenyl-dipropylamin
  • n-ethyl-3,3’-diphenyldipropylamine
  • N-Ethyl-3,3'-diphenyldipropylamine
  • N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine
  • n-ethyl-n-(3-phenylpropyl)-benzenepropanamin
  • phenpropamine
  • sestronbase
  • ALVERINE
  • DIPROPYLINE
  • BIS(GAMMA-PHENYLPROPYL)ETHYLAMINE
  • Bis(gamma-phenylpropyl)ethylamine Dipropyline Phenopropamine Profenil Sestron
  • Alverine base
  • N-Ethyl-N-(3-phenylpropyl)benzenepropan-1-amine
  • Seston base
  • Alverine (free base)
  • PHENOPROPAMINE
  • PROFENIL
  • Alverine in isooctane
  • N-ETHYL-3,3'-DIPHENYLDIPROPYLAMINE
  • 150-59-4