Alverine
- Product Name
- Alverine
- CAS No.
- 150-59-4
- Chemical Name
- Alverine
- Synonyms
- SESTRON;ALVERINE;PROFENIL;dipropylin;sestronbase;DIPROPYLINE;Seston base;phenpropamine;Alverine base;PHENOPROPAMINE
- CBNumber
- CB5333673
- Molecular Formula
- C20H27N
- Formula Weight
- 281.44
- MOL File
- 150-59-4.mol
Alverine Property
- Melting point:
- <25 °C
- Boiling point:
- bp0.3 165-168°; bp13 210-215°
- Density
- 0.973±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 9.51±0.50(Predicted)
- NIST Chemistry Reference
- Benzenepropanamine, n-ethyl-n-(3-phenylpropyl)-(150-59-4)
Safety
- Hazardous Substances Data
- 150-59-4(Hazardous Substances Data)
- Toxicity
- women,TDLo,oral,126mg/kg/5W-I (126mg/kg),BEHAVIORAL: ANOREXIA (HUMANLIVER: LIVER FUNCTION TESTS IMPAIREDLIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE",Journal of Hepathology. Vol. 27, Pg. 399, 1997.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R278459
- Product name
- N-ETHYL-3,3''-DIPHENYLDIPROPYLAMINE
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $106
- Updated
- 2023/06/20
- Product number
- 098071
- Product name
- Alverine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $341
- Updated
- 2021/12/16
- Product number
- V0596
- Product name
- Alverine
- Packaging
- 250mg
- Price
- $510
- Updated
- 2021/12/16
- Product number
- 098071
- Product name
- Alverine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $756
- Updated
- 2021/12/16
- Product number
- API0005666
- Product name
- 4-HYDROXY-1-OXO-ALVERINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $780.15
- Updated
- 2021/12/16
Alverine Chemical Properties,Usage,Production
Originator
Alverine citrate,Kemikos
Uses
Anticholinergic.
Definition
ChEBI: A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel synd ome.
Manufacturing Process
2 Methods of producing of alverine:
1. 3-Phenylpropylchloride reacted with ethylamine in the presence potassium
hydroxide and N-ethyl-3,3'-diphenyldipropylamine (alverine) was obtained.
2. 3-Phenylpropenal reacted with ethylamine in the presence hydrogen and Pt
as catalyst and BaSO4 and N-ethyl-3,3'-diphenyldipropylamine (alverine) was
obtained.
In practice it is usually used as citrate.
Therapeutic Function
Anticholinergic, Spasmolytic
Alverine Preparation Products And Raw materials
Raw materials
Preparation Products
Alverine Suppliers
- Tel
- --
- Fax
- --
- chiron@chiron.no
- Country
- Norway
- ProdList
- 2801
- Advantage
- 72
View Lastest Price from Alverine manufacturers
- Product
- alverine 150-59-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-09