4-Chlorobutyronitrile

Product Name: 4-Chlorobutyronitrile
CAS No.: 628-20-6
Chemical Name: 4-Chlorobutyronitrile
Synonyms: NSC 8410;orobutyronitriL;4- chloridenitrile;chlorobutyronitrile;4-Chlorbutyronitrile;4-chloro-butyronitril;4-chloro-butanenitril;4-CHLOROBUTANENITRILE;4-CHLOROBUTYRONITRILE;4-Chlorobutyronitryle
CBNumber: CB5336836
Molecular Formula: C4H6ClN
Formula Weight: 103.55
MOL File: 628-20-6.mol

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4-Chlorobutyronitrile Property

Boiling point:: 195-197 °C (lit.)
Density: 1.095 g/mL at 20 °C
refractive index: n20/D 1.442(lit.)
Flash point:: 185 °F
storage temp.: Inert atmosphere,Room Temperature
solubility: Chloroform, Ethyl Acetate (Slightly)
form: Liquid
Specific Gravity: 1.158
color: Clear colorless to pale yellow
Water Solubility: immiscible
BRN: 1633582
InChIKey: ZFCFBWSVQWGOJJ-UHFFFAOYSA-N
CAS DataBase Reference: 628-20-6(CAS DataBase Reference)
NIST Chemistry Reference: Butanenitrile, 4-chloro-(628-20-6)
EPA Substance Registry System: 4-Chlorobutyronitrile (628-20-6)

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Safety

Hazard Codes: T,Xi
Risk Statements: 25-36/37/38
Safety Statements: 45-7-36/37/39
RIDADR: UN 3276 6.1/PG 3
WGK Germany: 3
RTECS: ET9020000
Hazard Note: Irritant
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29269095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C30000
Product name: 4-Chlorobutyronitrile
Purity: 97%
Packaging: 100g
Price: $100
Updated: 2025/07/31

Sigma-Aldrich

Product number: C30000
Product name: 4-Chlorobutyronitrile
Purity: 97%
Packaging: 500g
Price: $293
Updated: 2023/06/20

TCI Chemical

Product number: C0925
Product name: 4-Chlorobutyronitrile
Purity: >97.0%(GC)
Packaging: 25mL
Price: $35
Updated: 2025/07/31

TCI Chemical

Product number: C0925
Product name: 4-Chlorobutyronitrile
Purity: >97.0%(GC)
Packaging: 500mL
Price: $558
Updated: 2025/07/31

TRC

Product number: C365041
Product name: 4-Chlorobutyronitrile
Packaging: 100g
Price: $85
Updated: 2021/12/16

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4-Chlorobutyronitrile Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Liquid. 4-Chlorobutyronitrile [628-20-6], 4- chlorobutanenitrile, Cl (CH2 )3CN, Mr 103.55, bp 189 – 191℃ (101.3 kPa), d154 1.0934, n20D 1.4413, is a liquid, miscible with ethanol and diethyl ether; it is immiscible with water.

Uses

4-Chlorobutyronitrile (cas# 628-20-6) is a compound useful in organic synthesis.

Production Methods

4-Chlorobutyronitrile is readily obtained by reacting 1-bromo-3-chloropropane with sodium cyanide. It is used in the synthesis of the pharmaceuticals buflomedil and buspirone. 4-Chlorobutyronitrile also yields cyclopropanecarbonitrile upon cyclization with base.

General Description

A liquid. Flash point 85°F. Density about 9.7 lb / gal and practically insoluble in water (2 parts/100 parts water). Hence sinks in water. Vapors are heavier than air. Irritates the eyes but not to the skin. Releases hydrogen chloride, hydrogen cyanide, and hydrogen bromide gases when heated or involved in a fire.

Air & Water Reactions

Highly flammable. Practically insoluble in water.

Reactivity Profile

4-Chlorobutyronitrile may attack some forms of plastics [USCG, 1999].

Health Hazard

Chemical is moderately toxic. Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes causes irritation. Can penetrate the skin on prolonged contact; only slightly irritating.

Fire Hazard

Special Hazards of Combustion Products: Toxic and irritating hydrogen cyanide, hydrogen bromide, and hydrogen chloride may form in fires.

4-Chlorobutyronitrile Preparation Products And Raw materials

Raw materials

1-Bromo-3-chloropropane POTASSIUM CYANIDE

Preparation Products

2-(Thien-2-yl)pyrrolidine 2-(3-BROMO-PROPYL)-1H-BENZOIMIDAZOLE 4-DIMETHYLAMINOBUTYLAMINE 4-Aminobutyric acid 4-(DIETHYLAMINO)BUTYLAMINE Cyclopropanecarboxylic acid

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4-Chlorobutyronitrile Suppliers

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View Lastest Price from 4-Chlorobutyronitrile manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Chlorobutyronitrile 628-20-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-17

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Chlorobutyronitrile 628-20-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Chlorobutyronitrile 628-20-6
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

628-20-6, 4-ChlorobutyronitrileRelated Search:

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best offer 4-Chlorobutyronitrile

628-20-6

C5H8NCl

ClCH23CN

C4H6CIN

ClC3H6CN

C4H6ClN

Organic Building Blocks

Nitrogen Compounds

Cyanides/Nitriles

NITRILE

C1 to C5

Building Blocks

API Intermediate

Aliphatics

Halogen compounds

Miscellaneous

C1 to C5

Cyanides/Nitriles

Nitrogen Compounds