ChemicalBook > CAS DataBase List > YKL 06-061

YKL 06-061

Product Name
YKL 06-061
CAS No.
2172617-15-9
Chemical Name
YKL 06-061
Synonyms
YKL 06-061;YKL 06-061 ，S0051;YKL-06-061, 10 mM in DMSO;YKL-06-061; YKL06-061; YKL 06-061; YKL-06061; YKL06061; YKL 06061;YKL 06 061,Salt-inducible Kinase (SIK),inhibit,Inhibitor,YKL06061;Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-
CBNumber
CB53375977
Molecular Formula
C30H37N7O2
Formula Weight
527.66
MOL File
2172617-15-9.mol
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YKL 06-061 Property

Boiling point:
719.8±70.0 °C(Predicted)
Density 
1.268±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C, protect from light, stored under nitrogen
solubility 
DMSO: 62.5 mg/mL (118.45 mM); Water: < 0.1 mg/mL (insoluble)
form 
Solid
pka
7.76±0.42(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0069399
Product name
YKL-06-061
Purity
99.89%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0069399
Product name
YKL-06-061
Purity
99.89%
Packaging
10mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0069399
Product name
YKL-06-061
Purity
99.89%
Packaging
50mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0069399
Product name
YKL-06-061
Purity
99.89%
Packaging
100mg
Price
$810
Updated
2021/12/16
DC Chemicals
Product number
DC10778
Product name
YKL-06-061
Purity
>98%
Packaging
250mg
Price
$950
Updated
2021/12/16
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YKL 06-061 Chemical Properties,Usage,Production

Uses

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].

IC 50

SIK1

References

[1] Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184. DOI:10.1016/j.celrep.2017.05.042

YKL 06-061 Preparation Products And Raw materials

Raw materials

Preparation Products

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YKL 06-061 Suppliers

China 59 United States 4 Global 63
ZHIWE CHEMTECH CO LTD
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View Lastest Price from YKL 06-061 manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
YKL 06-061 2172617-15-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-25
Career Henan Chemical Co
Product
YKL 06-061 2172617-15-9
Price
US $1.00/KG
Min. Order
1KG
Purity
98-99.9%
Supply Ability
100kg
Release date
2020-02-03

2172617-15-9, YKL 06-061Related Search:

YKL-5-124 yk11 YK-4-279 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE YL 0919 YH239-EE Y27632 (hydrochloride) Y320 YS 49 Yhhu-3792 YC-1 YKP-3089 BenzaMide, N-[4-chloro-3-(trifluoroMethyl)phenyl]-2-[2-(diMethylaMino)ethoxy]-6-ethoxy- YKL-06-062 YKL-05-099

  • YKL 06-061
  • YKL-06-061; YKL06-061; YKL 06-061; YKL-06061; YKL06061; YKL 06061
  • Pyrimido[4,5-d]pyrimidin-2(1H)-one, 1-cyclobutyl-3-(2,6-dimethylphenyl)-3,4-dihydro-7-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-
  • YKL 06 061,Salt-inducible Kinase (SIK),inhibit,Inhibitor,YKL06061
  • YKL-06-061, 10 mM in DMSO
  • YKL 06-061 ，S0051
  • 2172617-15-9
  • C30H37N7O2
  • API