S- (+)-Rolipram

Product Name: S- (+)-Rolipram
CAS No.: 85416-73-5
Chemical Name: S- (+)-Rolipram
Synonyms: (+)-Rolipram;(S)-(+)-ROLIPRAM;Rolipram (S)-(+)-;S- (+)-Rolipram (ME-3167;(+)-ROLIPRAM;(S)-ROLIPRAM;S- (+)-Rolipram USP/EP/BP;Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）;(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone;(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone
CBNumber: CB5397417
Molecular Formula: C16H21NO3
Formula Weight: 275.34
MOL File: 85416-73-5.mol

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S- (+)-Rolipram Property

Melting point:: 133-136℃
Density: 1.155
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMSO : 100 mg/mL (363.19 mM; Need ultrasonic)
form: White to off-white solid.
color: White to Almost white

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Safety

HS Code: 2933.79.1500

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: R0183
Product name: (S)-(+)-Rolipram
Purity: >98.0%(HPLC)
Packaging: 10mg
Price: $178
Updated: 2024/03/01

TCI Chemical

Product number: R0183
Product name: (S)-(+)-Rolipram
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $622
Updated: 2024/03/01

TRC

Product number: R640045
Product name: S-(+)-Rolipram
Packaging: 10mg
Price: $200
Updated: 2021/12/16

ApexBio Technology

Product number: A4349
Product name: S-(+)-Rolipram
Packaging: 25mg
Price: $190
Updated: 2021/12/16

AK Scientific

Product number: X5034
Product name: S-(+)-Rolipram
Packaging: 50mg
Price: $232
Updated: 2021/12/16

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S- (+)-Rolipram Chemical Properties,Usage,Production

Uses

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer

Uses

S-(+)-Rolipram is an inhibitor of cyclic AMP-specific phosphodiesterase. It is the S isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor

Definition

ChEBI: The (S)-enantiomer of rolipram.

Biological Activity

Less active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ).

storage

Room temperature

S- (+)-Rolipram Preparation Products And Raw materials

Raw materials

Preparation Products

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S- (+)-Rolipram Suppliers

China 56 Germany 3 India 2 Japan 1 The Netherlands 1 United Kingdom 6 United States 19 Global 88

MedChemexpress LLC

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TargetMol Chemicals Inc.

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Alfa Chemistry

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InvivoChem

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Aladdin Scientific

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TargetMol Chemicals Inc.

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Creative Enzymes

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Santa Cruz Biotechnology, Inc.

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BIOMOL INTERNATIONAL, LP

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View Lastest Price from S- (+)-Rolipram manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: S- (+)-Rolipram 85416-73-5
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99% HPLC
Supply Ability: 2000tons
Release date: 2019-12-30

Career Henan Chemical Co

Product: S- (+)-Rolipram 85416-73-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100KG
Release date: 2020-03-13

85416-73-5, S- (+)-RolipramRelated Search:

ZARDAVERINE RO 20-1724 Roflumilast 4-(3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL)PYRROLIDIN-2-ONE ETAZOLATE BRL 50481 Vinpocetine ZAPRINAST Cilostazol CILOSTAMIDE AG 1295 (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE 4-[[3,4-(METHYLENEDIOXY)BENZYL]AMINO]-6-CHLOROQUINAZOLINE EHNA HYDROCHLORIDE S- (+)-Rolipram 4-(3'-Methoxyphenyl)-2-pyrrolidinone 4-(4'-Methoxyphenyl)-2-pyrrolidinone 1-(4-bromobenzyl)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

(S)-(+)-ROLIPRAM

(4S)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one

Rolipram (S)-(+)-

(4S)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(+)-ROLIPRAM;(S)-ROLIPRAM

(4S)-4-[3-(cyclopentoxy)-4-methoxy-phenyl]-2-pyrrolidone

(S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

(4S)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone

2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4S)-

(S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one

S- (+)-Rolipram USP/EP/BP

S- (+)-Rolipram (ME-3167

(+)-Rolipram

TNFα,tumor,inhibit,(S)(+)Rolipram,mononuclear,Apoptosis,phosphodiesterase,(S) (+) Rolipram,Phosphodiesterase (PDE),cAMP,Inhibitor,factor,necrosis

Risperidone Impurity 4-d4（Risperidone EP Impurity D-d4）

85416-73-5

Signalling

Cyclic Nucleotide related

Inhibitors