ChemicalBook > CAS DataBase List > 2-Chloroquinoline

2-Chloroquinoline

Product Name
2-Chloroquinoline
CAS No.
612-62-4
Chemical Name
2-Chloroquinoline
Synonyms
2CQ;2-chloro-quinolin;2-CHLOROQUINOLINE;Quinoline2-chloro-;2-Chloroquinoline,99%;2-Chloroquinoline >2-Chloroquinoline, 98%+;2-Chloroquinoline ,99.70%;2-Chloroquinoline, 99% 5GR;2-Chloroquinoline, 99% 1GR
CBNumber
CB5403688
Molecular Formula
C9H6ClN
Formula Weight
163.6
MOL File
612-62-4.mol
More
Less

2-Chloroquinoline Property

Melting point:
34-37 °C (lit.)
Boiling point:
266-267 °C (lit.)
Density 
1.23 g/mL at 25 °C (lit.)
refractive index 
1.6342 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
form 
Crystalline Powder, Crystals and/or Chunks or Fused Mass
pka
0.41±0.40(Predicted)
color 
White to yellow
Water Solubility 
Insoluble
BRN 
112561
InChIKey
OFUFXTHGZWIDDB-UHFFFAOYSA-N
CAS DataBase Reference
612-62-4(CAS DataBase Reference)
NIST Chemistry Reference
Quinoline, 2-chloro-(612-62-4)
EPA Substance Registry System
Quinoline, 2-chloro- (612-62-4)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
VB2320000
F 
8
TSCA 
Yes
HS Code 
29334900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C70401
Product name
2-Chloroquinoline
Purity
99%
Packaging
5g
Price
$147.6
Updated
2024/03/01
Sigma-Aldrich
Product number
C70401
Product name
2-Chloroquinoline
Purity
99%
Packaging
1g
Price
$89.5
Updated
2023/06/20
TCI Chemical
Product number
C0282
Product name
2-Chloroquinoline
Purity
>98.0%(GC)
Packaging
5g
Price
$66
Updated
2024/03/01
TCI Chemical
Product number
C0282
Product name
2-Chloroquinoline
Purity
>98.0%(GC)
Packaging
25g
Price
$262
Updated
2024/03/01
Alfa Aesar
Product number
B23443
Product name
2-Chloroquinoline, 99%
Packaging
25g
Price
$252
Updated
2021/12/16
More
Less

2-Chloroquinoline Chemical Properties,Usage,Production

Chemical Properties

white to yellowish crystals, powder, chunks or

Uses

2-Chloroquinoline is an intermediate used in the synthesis of various compounds that exhibits antifungal properties.

Uses

2-Chloroquinoline is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. It reacts with benzotriazole, followed by cyclization with loss of nitrogen, gives the indolo[2,3-b]quinoline ring system for use in novel cytotoxic DNA topoisomerase II inhibitors.

Synthesis Reference(s)

The Journal of Organic Chemistry, 67, p. 7884, 2002 DOI: 10.1021/jo016196i
Synthesis, p. 1013, 1987 DOI: 10.1055/s-1987-28152

Purification Methods

Purify it by crystallisation of its picrate to constant melting point (123-124o) from *benzene, regenerating the base and distilling it under vacuum [Cumper et al. J Chem Soc 1183 1962]. 2-Chloroquinoline can be crystallised from EtOH. Its picrate has m 123-124o (from EtOH). [Beilstein 20 H 359, 20/7 V 312.]

2-Chloroquinoline Preparation Products And Raw materials

Raw materials

Quinoline Ethanol Acetic anhydride N,N-Dimethylformamide Cesium carbonate Hydrogen peroxide Toluene Acetyl chloride Trichloroisocyanuric acid Phosphorus oxychloride Triethylamine 2-Quinolinol 1,4-Dioxane Tosyl chloride Phosphorus trichloride Benzene N-Chlorosuccinimide Ethyl acetate 2-Aminobenzaldehyde Hydrochloric acid Acetic acid Triphenylphosphine Pyridine

Preparation Products

More
Less

2-Chloroquinoline Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 220 Europe 2 Germany 4 India 4 Japan 3 Slovakia 1 Switzerland 1 The Netherlands 1 Ukraine 1 United Kingdom 13 United States 41 Global 295
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
More
Less

View Lastest Price from 2-Chloroquinoline manufacturers

Henan Fengda Chemical Co., Ltd
Product
Chloroquinoline 612-62-4
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Henan Aochuang Chemical Co.,Ltd.
Product
2-Chloroquinoline 612-62-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27
Hebei Zhanyao Biotechnology Co. Ltd
Product
2-Chloroquinoline 612-62-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-14

612-62-4, 2-ChloroquinolineRelated Search:

CHLOROQUINE quinolinium hydrogen sulphate Quinhydrone 6-Hydroxy-2(1H)-3,4-dihydroquinolinone 8-Hydroxyquinoline Isoquinoline 4-Chloroquinoline Ethoxyquin Quinclorac 7-CHLOROQUINOLINE 2-CHLOROQUINOLINE-4-CARBOXYLIC ACID 6-BROMO-2-CHLOROQUINOLINE-4-CARBONYL CHLORIDE 2-CHLOROQUINOLINE-3-CARBALDEHYDE 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 2-CHLORO-6-METHOXYQUINOLINE-3-CARBALDEHYDE 2-CHLOROLEPIDINE 2-Chloro-3-methylquinoline 8-Chloroquinoline ,99%

  • 2-chloro-quinolin
  • Quinoline2-chloro-
  • 2-CHLOROQUINOLINE
  • 2CQ
  • 2-Chloroquinoline,99%
  • 2-Chloroquinoline ,99.70%
  • 2-Chloroquinoline, 99% 1GR
  • 2-Chloroquinoline, 99% 5GR
  • 2-Chloroquinoline, 98%+
  • 1,3-Propanediamine, N'-(7-chloro-4-quinolinyl)-N,N-dimethyl-
  • 1-(Quinolin-2-yl)-1H-pyrazole-4-carboxylic acid
  • 2-Chloroquinoline &gt
  • 2-Chloroquinoline ISO 9001：2015 REACH
  • TIANFU CHEM --2-Chloroquinoline_
  • 612-62-4
  • C9ClH6N
  • Building Blocks
  • HETERO CHLORIDE
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Quinolines
  • Haloquinolines
  • Quinolines, Quinazolines and derivatives
  • Quinoline&Isoquinoline
  • Organohalides
  • Quinoline
  • Haloquinolines
  • Quinolines
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • QuinolinesHeterocyclic Building Blocks
  • Halides
  • Heterocycles