VISNAGIN

Product Name: VISNAGIN
CAS No.: 82-57-5
Chemical Name: VISNAGIN
Synonyms: VISNAGIN;visnagine;visnagidin;VISNAGIN(P);VISNAGIN(RG);Metofuroxime;desmethoxykhellin;VISNAGIN USP/EP/BP;LABOTEST-BB LT00441024;Visnagin, 10 mM in DMSO
CBNumber: CB5434295
Molecular Formula: C13H10O4
Formula Weight: 230.22
MOL File: 82-57-5.mol

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VISNAGIN Property

Melting point:: 139-142 °C
Boiling point:: 292.2°C (rough estimate)
Density: 1.1302 (rough estimate)
refractive index: 1.4300 (estimate)
storage temp.: 2-8°C
solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).
form: Fine Crystalline Powder
color: Beige
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
LogP: 2.260 (est)
CAS DataBase Reference: 82-57-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
RTECS: LV1420000
HS Code: 29162000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T341649
Product name: VISNAGIN
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2024/03/01

TRC

Product number: V675008
Product name: Visnagin
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FV42573
Product name: Visnagin
Packaging: 5G
Price: $100
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb546235
Product name: Visnagin
Purity: >98%
Packaging: 25mg
Price: $127.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FV42573
Product name: Visnagin
Packaging: 10g
Price: $175
Updated: 2021/12/16

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VISNAGIN Chemical Properties,Usage,Production

Description

Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga.? It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in a decrease in cardiomyocyte apoptosis.1

Chemical Properties

BEIGE FINE CRYSTALLINE POWDER

Uses

antiinflammatory, neuroprotective

Definition

ChEBI: Visnagin is a furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. It has a role as a phytotoxin, an EC 1.1.1.37 (malate dehydrogenase) inhibitor, a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a plant metabolite. It is a furanochromone, an aromatic ether and a polyketide. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.

Purification Methods

Crystallise visnagin from water. It is soluble in CHCl3 but slightly soluble in EtOH. [Aneja et al. Tetrahedron 3 230 1958, Beilstein 19 III/IV 2640.]

References

1) Liu et al. (2014), Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase; Sci. Transl. Med. 6 266ra170

VISNAGIN Preparation Products And Raw materials

Raw materials

Preparation Products

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VISNAGIN Suppliers

Belgium 1 China 69 Germany 3 India 2 Japan 1 Switzerland 1 United Kingdom 9 United States 11 USA 1 Global 98

EMMX Biotechnology LLC

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Focus Biomolecules

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Cayman Chemical Company

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INDOFINE Chemical Company, Inc.

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2A PharmaChem USA

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HONEST JOY HOLDINGS LIMITED

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3B Scientific Corporation

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ChromaDex

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82-57-5, VISNAGINRelated Search:

beta-Sitosterol Hydroxyecdysone Epimedium P.E Icariin 10%,20% HPLC VISNAGIN khelloside VISNAGIN MRS 1065 CHEMBRDG-BB 5160161 4,9-Dimethoxy-7-(2-phenylethenyl)-5H-furo[3,2-g][1]<br>benzopyran-5-one azaspirium chloride Timefurone Mecrifurone 4,9-DIMETHOXY-7-(1,1,2,2-TETRAFLUOROETHYL)-5H-FURO-[3,2-G]-CHROMENE-5-ONE 4,9-DIMETHOXY-7-(TRICHLOROMETHYL)-5H-FURO[3,2-G]CHROMEN-5-ONE 4,9-DIETHOXY-7-METHYL-FURO[3,2-G]CHROMEN-5-ONE 4,9-DIMETHOXY-7-(TRIFLUOROMETHYL)-5H-FURO[3,2-G]CHROMEN-5-ONE 7-DIFLUOROMETHYL-4,9-DIMETHOXY-5H-FURO-[3,2-G]-CHROMENE-5-ONE 4,9-DIMETHOXY-7-PENTAFLUOROETHYL-5H-FURO-[3,2-G]-CHROMENE-5-ONE

5-METHOXY-2-METHYL-FURANOCHROMONE

4-METHOXY-7-METHYL-5H-FURO[3,2-G][1]-BENZOPYRAN-5-ONE

4-METHOXY-7-METHYL-FURO[3,2-G]CHROMEN-5-ONE

LABOTEST-BB LT00441024

VISNAGIN

2-g)(1)benzopyran-5-one,4-methoxy-7-methyl-5h-furo(

desmethoxykhellin

visnagidin

visnagine

VISNAGIN(RG)

4-METHOXY-7-METHYL-5H-FURO[3,2-G][1]-BENZOPYRAN-5-ONE 97%

4-METHOXY-7-METHYL-5H-FURO3,2-Ga1a-BENZOPYRAN-5-ONE, 97%

4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one,97%

4-Methoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-oneVisnagin

4-Methoxy-7-methyl-5H-furo

VISNAGIN(P)

Metofuroxime

5H-Furo[3,2-g][1]benzopyran-5-one, 4-methoxy-7-methyl-

VISNAGIN USP/EP/BP

Visnagin, 10 mM in DMSO

82-57-5

Heterocyclic Building Blocks

Coumarins

Building Blocks

Chromones