ChemicalBook > CAS DataBase List > H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2

H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2

Product Name
H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2
CAS No.
127650-08-2
Chemical Name
H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2
Synonyms
CADHERIN PEPTIDE (AVIAN);CADHERIN-1 (76-85) AMIDE (CHICKEN);N-CADHERIN (76-85) AMIDE (CHICKEN);NEURAL-CADHERIN (76-85) AMIDE (CHICKEN);LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2;H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2;Cadherin-1 (76-85) aMide (chicken), N-Cadherin (76-85) aMide (chicken);Glycinamide, L-leucyl-L-arginyl-L-alanyl-L-histidyl-L-alanyl-L-valyl-L-α-aspartyl-L-valyl-L-asparaginyl-
CBNumber
CB5462366
Molecular Formula
C44H75N17O13
Formula Weight
1050.17
MOL File
127650-08-2.mol
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H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2 Property

Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
-15°C
solubility 
insoluble in EtOH; ≥105 mg/mL in DMSO; ≥15.63 mg/mL in H2O
pka
4.19±0.10(Predicted)
form 
Solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A1028
Product name
Cadherin Peptide, avian
Packaging
1mg
Price
$45
Updated
2021/12/16
ApexBio Technology
Product number
A1028
Product name
Cadherin Peptide, avian
Packaging
5mg
Price
$135
Updated
2021/12/16
ApexBio Technology
Product number
A1028
Product name
Cadherin Peptide, avian
Packaging
10mg
Price
$225
Updated
2021/12/16
ApexBio Technology
Product number
A1028
Product name
Cadherin Peptide, avian
Packaging
25mg
Price
$315
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364457
Product name
Cadherin Peptide (Avian)
Purity
> 95%
Packaging
1mg
Price
$353.6
Updated
2021/12/16
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H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2 Chemical Properties,Usage,Production

Uses

Cadherin Peptide, avian is a calcium-dependent glycoprotein. Cadherin Peptide, avian takes part in homophilic cell-cell adhesion and dose-dependently inhibits bovine brain microvessel endothelial cells (BBMECs) adhesion[1].

Biological Activity

cadherin peptide, avian, (c44h75n17o13), a peptide with the sequence leu-arg-ala-his-ala-val-asp-val-asn-gly-nh2, mw= 1050.2. cadherins (named for "calcium-dependent adhesion") are a class of type-1 transmembrane proteins. they play important roles in cell adhesion, ensuring that cells within tissues are bound together. they are dependent on calcium (ca2+) ions to function. cadherins are synthesized as polypeptides and undergo many post-translational modifications to become the proteins which mediate cell-cell adhesion and recognition. cadherins behave as both receptors and ligands. during development, their behavior assists in properly positioning cells - they are responsible for the separation of the different tissue layers, and for cellular migration. in the very early stages of development, e-cadherin (epithelial cadherin) is most greatly expressed. during the next stage, the development of the neuronal plate, n-cadherin (neural cadherin) is expressed and there is a decrease in e-cadherin. finally, during the development of the notochord and the condensation of somites, e- p- and n-cadherin expression increases. after development, cadherins play a role in maintaining cell and tissue structure, and in cellular movement.figure1 formula of b-interleukin ii (44-56)figure2 the organisation of the cadherin-catenin complex

References

1. Harris, Tony J.C., and Ulrich Tepass. "Adherins Junctions: From Molecules to Morphogenesis" Nature Reviews Molecular Cell Biology. 502-514. July 20102. Tepass, Ulrich, et al. "Cadherins in Embryonic and Neural Morphogenisis" Nature Reviews Molecular Cell Biology. November 2000.3. Tepass, Ulrich, et al. "Cadherins in Embryonic and Neural Morphogenisis" Nature Reviews Molecular Cell Biology. November 2000.

H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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127650-08-2, H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2Related Search:


  • N-CADHERIN (76-85) AMIDE (CHICKEN)
  • NEURAL-CADHERIN (76-85) AMIDE (CHICKEN)
  • LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2
  • CADHERIN-1 (76-85) AMIDE (CHICKEN)
  • CADHERIN PEPTIDE (AVIAN)
  • H-LEU-ARG-ALA-HIS-ALA-VAL-ASP-VAL-ASN-GLY-NH2
  • Cadherin-1 (76-85) aMide (chicken), N-Cadherin (76-85) aMide (chicken)
  • Glycinamide, L-leucyl-L-arginyl-L-alanyl-L-histidyl-L-alanyl-L-valyl-L-α-aspartyl-L-valyl-L-asparaginyl-
  • 127650-08-2
  • C44H75N17O13
  • CancerBiology