N-(Trimethylsilyl)imidazole

Product Name: N-(Trimethylsilyl)imidazole
CAS No.: 18156-74-6
Chemical Name: N-(Trimethylsilyl)imidazole
Synonyms: TMSI;TMSIM;TRIMETHYLSILYLIMIDAZOLE;TSIM;TMS-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE;SIM;1-(TRIMETHYLSILYL)-1H-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%;Trimethylimidazosilane
CBNumber: CB5483743
Molecular Formula: C6H12N2Si
Formula Weight: 140.26
MOL File: 18156-74-6.mol

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N-(Trimethylsilyl)imidazole Property

Melting point:: -42 °C
Boiling point:: 93-94 °C14 mm Hg(lit.)
Density: 0.957 g/mL at 20 °C
refractive index: n20/D 1.475(lit.)
Flash point:: 42 °F
storage temp.: Store below +30°C.
solubility: Chloroform
form: Liquid
pka: 7.96±0.10(Predicted)
Specific Gravity: 0.956
color: Clear colorless to yellow
Water Solubility: decomposes
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
BRN: 606148
Stability:: Air and Moisture Sensitive
InChIKey: YKFRUJSEPGHZFJ-UHFFFAOYSA-N
CAS DataBase Reference: 18156-74-6(CAS DataBase Reference)
NIST Chemistry Reference: 1h-Imidazole, 1-(trimethylsilyl)-(18156-74-6)
EPA Substance Registry System: 1H-Imidazole, 1-(trimethylsilyl)- (18156-74-6)

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Safety

Hazard Codes: F,Xi,C
Risk Statements: 11-36/37/38-14-40-34-37-35-20/21/22
Safety Statements: 16-26-33-37/39-45-36/37/39
RIDADR: UN 1993 3/PG 2
WGK Germany: 3
RTECS: NI8700000
F: 10-21
Autoignition Temperature: 540 °C DIN 51794
TSCA: T
HazardClass: 3
PackingGroup: II
HS Code: 29332990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.18204
Product name: N-(Trimethylsilyl)imidazole
Purity: for synthesis
Packaging: 25mL
Price: $88.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.18204
Product name: N-(Trimethylsilyl)imidazole
Purity: for synthesis
Packaging: 100mL
Price: $267
Updated: 2024/03/01

Sigma-Aldrich

Product number: 153583
Product name: 1-(Trimethylsilyl)imidazole
Purity: 96%
Packaging: 5ml
Price: $48.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 153583
Product name: 1-(Trimethylsilyl)imidazole
Purity: 96%
Packaging: 25ml
Price: $128
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1.09771
Product name: N-(Trimethylsilyl)imidazole
Purity: for gas chromatography
Packaging: 5ml
Price: $214
Updated: 2024/03/01

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N-(Trimethylsilyl)imidazole Chemical Properties,Usage,Production

Chemical Properties

Colorless transparent liquid

Physical properties

bp 93–94 °C/14 mmHg; fp 5 °C; d 0.956 g cm?3.

Uses

A general silylating agent, particularly for alcohols. An intermediate for the synthesis of imidazole derivatives.

Uses

Silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.1

Uses

N-(trimethylsilyl) imidazole (TMSim) is quite reactive with hydroxyl groups in a variety of analytes including a variety of lipids.As with other derivatization reactions,microwave heating can greatly improve process efficiency.

Uses

N-(Trimethylsilyl)imidazole is a silylating agent for alcohols and 1,3-dicarbonyl compounds; reaction with esters to give imidazolides; preparation of O-trimethylsilyl monothioacetals; aromatization of the A-ring of steroids. It participates in the reactions of Hydroxyl Silylation Reactions, Silyl Aminal Formation Reactions, Nitrogen Silylation Reactions, Acyl Imidazole Formation, Michael Addition Reactions, Substitution Reactions, Phosphoroimidazolidate Formation, and other uses.

Definition

ChEBI: A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a trimethylsilyl group. N-trimethylsilylimidazole is a derivatisation agent used in gas chromatography/mass spectrometry applications.

General Description

1-(Trimethylsilyl)imidazole (TMSIM) has high silyl donor ability. It does not react with amino groups and also does not help in formation of enol-ether on unprotected ketone groups. It is useful as a silylating agent for ecdysones, norepinephrine, dopamine, steroids, sugars, sugar phosphates and ketose isomers.

N-(Trimethylsilyl)imidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Trimethylsilyl)imidazole Suppliers

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View Lastest Price from N-(Trimethylsilyl)imidazole manufacturers

HebeiShuoshengImportandExportco.,Ltd

Product: N-(Trimethylsilyl)imidazole 18156-74-6
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-08

Hubei Changfu Chemical Co., Ltd.

Product: N-(Trimethylsilyl)imidazole 18156-74-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 96%
Supply Ability: 20t
Release date: 2024-04-26

WUHAN FORTUNA CHEMICAL CO., LTD

Product: N-(Trimethylsilyl)imidazole 18156-74-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-01-16

18156-74-6, N-(Trimethylsilyl)imidazoleRelated Search:

(Trifluoromethyl)trimethylsilane Trimethylsilyl cyanide TRIMETHYLSILANE Potassium trimethylsilanolate Hexamethyldisilazane 1-Methylimidazole Imidazole Trimethylsilylacetylene Azidotrimethylsilane hydroxytrimethylsilane N-(Trimethylsilyl)acetamide Iodotrimethylsilane Pyridine sulfur trioxide Chlorotrimethylsilane Bromotrimethylsilane N-6,9-BIS(TRIMETHYLSILYL)ADENINE Silicon N-(TRIMETHYL-D9-SILYL)IMIDAZOLE

1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%

Trimethylimidazosilane

Trimethylsilylimidzole

1-(trimethylsilyl)-1h-imidazol

1-(trimethylsilyl)-imidazol

1-Imidazolyltrimethylsilane

CT3600

Imidazole, 1-(trimethylsilyl)-

Imidazole, N-(trimethylsilyl)-

N-(Trimethylsilyl)imidazol

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1-(TRIMETHYLSILYL)-1H-IMIDAZOLE

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N-(Trimethylsilyl)im

TMS-IMidazole (=N-TriMethylsilyliMidazole)

N-(TriMethylsilyl)-1H-iMidazole

NSC 139860

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