ChemicalBook > CAS DataBase List > CHLORMETHIAZOLE HYDROCHLORIDE

CHLORMETHIAZOLE HYDROCHLORIDE

Product Name
CHLORMETHIAZOLE HYDROCHLORIDE
CAS No.
6001-74-7
Chemical Name
CHLORMETHIAZOLE HYDROCHLORIDE
Synonyms
Somnevrin hydrochloride;CloMethiazole Hydrochloride;CHLORMETHIAZOLE HYDROCHLORIDE;Clomethiazole hydrochloride salt;Chlormethiazole Hydrochloride >4-methyl-5-(β-chloroethyl)thiazole hydrochloride;Inhibitor,Clomethiazole,Chlormethiazole hydrochloride,Chlormethiazole,inhibit;4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
CBNumber
CB5497315
Molecular Formula
C6H9Cl2NS
Formula Weight
198.11336
MOL File
6001-74-7.mol
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CHLORMETHIAZOLE HYDROCHLORIDE Property

Melting point:
130℃
storage temp. 
Desiccate at RT
solubility 
H2O: >10 mg/mL, soluble
form 
crystalline
color 
off-white
Merck 
14,2384
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xn
Risk Statements 
22-41-43
Safety Statements 
26-36/37/39
WGK Germany 
3
HS Code 
2934.10.2000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C1240
Product name
Chlormethiazole hydrochloride
Purity
≥98% (HPLC), powder
Packaging
10mg
Price
$57.2
Updated
2024/03/01
Sigma-Aldrich
Product number
C1240
Product name
Chlormethiazole hydrochloride
Purity
≥98% (HPLC), powder
Packaging
50mg
Price
$509
Updated
2024/03/01
TCI Chemical
Product number
C3020
Product name
Chlormethiazole Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
200mg
Price
$192
Updated
2024/03/01
TCI Chemical
Product number
C3020
Product name
Chlormethiazole Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$461
Updated
2024/03/01
TRC
Product number
C602013
Product name
Chlormethiazole hydrochloride
Packaging
50mg
Price
$215
Updated
2021/12/16
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CHLORMETHIAZOLE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Chlormethiazole Hydrochloride was used in the study of effect of thiazole methiodide and hydrochloride fractions of thiamine upon the neuromuscular system.

Biochem/physiol Actions

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: enhanced sedative effects.
Antivirals: concentration possibly increased by ritonavir.
Cimetidine: inhibits metabolism of clomethiazole.

Metabolism

Clomethiazole is extensively metabolised, probably by first-pass metabolism in the liver with only small amounts appearing unchanged in the urine. The rate of elimination is decreased by about 30% in liver cirrhosis.

CHLORMETHIAZOLE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CHLORMETHIAZOLE HYDROCHLORIDE Suppliers

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View Lastest Price from CHLORMETHIAZOLE HYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
CHLORMETHIAZOLE HYDROCHLORIDE 6001-74-7
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-08-04

6001-74-7, CHLORMETHIAZOLE HYDROCHLORIDERelated Search:


  • 4-methyl-5-(β-chloroethyl)thiazole hydrochloride
  • Somnevrin hydrochloride
  • 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
  • CloMethiazole Hydrochloride
  • Clomethiazole hydrochloride salt
  • Chlormethiazole Hydrochloride &gt
  • Inhibitor,Clomethiazole,Chlormethiazole hydrochloride,Chlormethiazole,inhibit
  • CHLORMETHIAZOLE HYDROCHLORIDE
  • 6001-74-7
  • C6H8ClNS
  • Heterocycles