ChemicalBook > CAS DataBase List > Nandrolone

Nandrolone

Product Name
Nandrolone
CAS No.
434-22-0
Chemical Name
Nandrolone
Synonyms
19-NORTESTOSTERONE;nortestosterone;NANDROLON;Nandrolone Base;NADROLONE;Nandrolone decanoat;C07254;NSC 3351;ndrolone;menidrabol
CBNumber
CB5681525
Molecular Formula
C18H26O2
Formula Weight
274.4
MOL File
434-22-0.mol
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Nandrolone Property

Melting point:
120-125 °C
alpha 
D22 +55° (c = 0.93 in chloroform)
Boiling point:
357.38°C (rough estimate)
Density 
1.0528 (rough estimate)
refractive index 
1.4800 (estimate)
Flash point:
2℃
storage temp. 
Controlled Substance, -20°C Freezer
solubility 
Acetonitrile: 1 mg/ml; Ethanol: 1 mg/ml; Methanol: 1 mg/ml
form 
A crystalline solid
pka
15.06±0.40(Predicted)
color 
Dimorphic crystals from CH2Cl2/Et2O
Water Solubility 
3.09g/L(25 ºC)
Merck 
6365
BRN 
2055849
InChIKey
NPAGDVCDWIYMMC-IZPLOLCNSA-N
CAS DataBase Reference
434-22-0(CAS DataBase Reference)
NIST Chemistry Reference
Nandrolone(434-22-0)
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Safety

Hazard Codes 
Xn,T,F
Risk Statements 
20/21/22-64-40-61-60-36-11-38-19
Safety Statements 
22-24/25-36/37/39-45-36/37-53-16
RIDADR 
UN 1648 3 / PGII
WGK Germany 
3
RTECS 
KG7964000
HS Code 
29372900
Hazardous Substances Data
434-22-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N-050
Product name
Nandrolone solution
Purity
1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$170
Updated
2024/03/01
Sigma-Aldrich
Product number
BP257
Product name
Nandrolone
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$255
Updated
2024/03/01
Sigma-Aldrich
Product number
1454008
Product name
Nandrolone
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$953
Updated
2024/03/01
Cayman Chemical
Product number
21173
Product name
Nandrolone
Purity
≥98%
Packaging
1mg
Price
$38
Updated
2024/03/01
Cayman Chemical
Product number
21173
Product name
Nandrolone
Purity
≥98%
Packaging
5mg
Price
$93
Updated
2024/03/01
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Nandrolone Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Originator

Durabolin,Organon,US,1959

Uses

An anabolic steroid. Controlled substance (anabolic steroid)

Definition

ChEBI: A 3-oxo Delta4-steroid that is estr-4-en-3-one substituted by a beta-hydroxy group at position 17.

Manufacturing Process

An ice-cold solution of 1.5 grams of 19-nortestosterone and 1.5 ml of dry pyridine in 10 ml of dry benzene is prepared and a solution of 1.5 ml of β- phenylpropionyl chloride in 5 ml of dry benzene is added dropwise over a period of about 2 minutes with stirring. The resulting mixture is allowed to stand overnight under an atmosphere of nitrogen and then washed successively with cold 5% aqueous hydrochloric acid solution, cold 2.5% aqueous sodium hydroxide solution, and water. After drying over anhydrous sodium sulfate, the solvent is evaporated to give an almost colorless oil. Recrystallization from methanol gives white crystals of 19-nortestosterone 17- β-phenylpropionate, MP 91° to 92.5°C.

Therapeutic Function

Anabolic

Mechanism of action

Nandrolone facilitates formation of body muscle mass and strengthens the process of osseous tissue development. The main indications for using nandrolone, as well as other anabolic steroids, are abnormal protein anabolism, asthenia, diseases accompanied by protein loss, adrenal insufficiency, steroid diabetes, and prolonged condition of sluggishness.

Safety Profile

Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.

Synthesis

Nandrolone, 17|?-hydroxyester-4-en-3-one (29.1.7), is made from estradiol (28.1.17). The phenol hydroxyl group undergoes methylation by dimethylsulfate in the presence of sodium hydroxide, forming the corresponding methyl ether (29.3.1), and then the aromatic ring is reduced by lithium in liquid ammonia, which forms an enol ether (29.3.2). Hydrolyzing this compound with a mixture of hydrochloric and acetic acids leads to the formation of a keto group, and simultaneous isomerization of the double bond from C5¨CC10 to position C4¨CC5 gives the desired nandrolone (29.3.3) [16¨C19]. Upon necessity of using it in the form of acid esters, the product is acylated by corresponding acid derivatives.

Nandrolone Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Nandrolone manufacturers

Hebei Jiafan Trading Company Limited
Product
Nandrolone 434-22-0
Price
US $5.00/Box
Min. Order
1Box
Purity
99.99%
Supply Ability
20000 boxes
Release date
2025-01-10
Hebei Mujin Biotechnology Co.,Ltd
Product
Nandrolone 434-22-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-11
hebei hongtan Biotechnology Co., Ltd
Product
Nandrolone base 434-22-0
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-16

434-22-0, NandroloneRelated Search:

Deprodone Nandrolone Decanoate Nandrolone phenylpropionate Trestolone Norbolethone Norethindrone Mibolerone Norclostebol Oxendolone Etonogestrel Levonorgestrel NANDROLONE LAURATE,NANDROLONE LAURATE, BP STANDARD,nandrolone dodecanoate 19-Nortestosterone 17-hemisuccinate Drostanolone propionate Stanolone Methenolone acetate Tibolone 19-Nortestosterone 4-hexyloxyphenylpropionate

  • NADROLONE
  • 17-beta-hydroxyoestr-4-en-3-one
  • 17-HYDROXY-13-METHYL-2,6,7,8,9,10,11,12,14,15,16,17-DODECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-ONE, 5-ANDROSTENEDIONE
  • 17b-hydroxyestra-4-en-3-one
  • 17BETA-HYDROXY-4-ESTREN-3-ONE
  • 17BETA-HYDROXY-19-NORANDROST-4-EN-3-ONE
  • 19-NORTESTOSTERONE
  • 19-NORANDROSTENOLONE
  • 19-NOR-4-ANDROSTEN-17-BETA-OL-3-ONE
  • menidrabol
  • norandrostenolon
  • nortestonate
  • nortestosterone
  • 4-ESTREN-17BETA-OL-3-ONE
  • NANDROLON
  • NANDROLONE
  • NORANDROSTENOLONE
  • NORTESTOSTERONE, 19-
  • (17beta)-estr-4-en-3-on
  • 17-beta-hydroestr-4-en-3-one
  • 17beta-hydroxy-19-nor-4-androsten-3-one
  • 17-beta-hydroxy-estr-4-en-3-on
  • 17beta-hydroxy-estr-4-en-3-on
  • 19-nortestosterone standard solution
  • 19-nortestosterone--dea schedule iii
  • Nandrolone Base
  • NANDROLON VETRANAL, 250 MG
  • NANDROLONE, MM(CRM STANDARD)
  • NANDROLONE, BP STANDARD
  • NANDROLONE, 99+%
  • NANDROLONE, USP STANDARD
  • NORTESTOSTERONE, 19-(REAGENT / STANDARD GRADE)
  • NandroloneCypionateBase
  • Nandrolone(19-Nortestosterone)
  • 17β-Hydroxyestra-4-en-3-one
  • 19-Nortestosterone, 17b-Hydroxy-4-estren-3-one,
  • 17β-hydroxy-19-norandrost-4-en-3-one
  • (8R,9S,10R,13S,14S,17S)-17-hydroxy-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-one
  • (17b)-19-Nortestosterone
  • 17b-Hydroxy-19-nor-4-androsten-3-one
  • 17b-Hydroxyestr-4-en-3-one
  • 17b-Nortestosterone
  • 19-Nor-17b-hydroxy-3-ketoandrost-4-ene
  • 4-Estren-17b-ol-3-one
  • 4-Estren-3-one-17b-ol
  • b-Nortestosterone
  • d-13b-Methyl-17b-hydroxygon-4-en-3-one
  • D4-Estren-17b-ol-3-one
  • Estr-4-en-3-one, 17b-hydroxy- (8CI)
  • Estr-4-en-3-one, 17-hydroxy-, (17b)- (9CI)
  • NSC 3351
  • Oestrenolon
  • 19-NORTESTOSTERONE 98+%
  • NANDROLONE:17BETA-HYDROXYESTRA-4-EN-3-ONE
  • (17)-17-Hydroxyestr-4-en-3-one
  • 17β-Hydroxy-19-norandrost-4-en-3-one, 17β-Hydroxy-4-estren-3-one, 19-Norandrostenolone, 4-Estren-17β-ol-3-one, Nadrolone, Nandrolone
  • 17β-Hydroxy-19-norandrost-4-en-3-one, 17β-Hydroxy-4-estren-3-one, 19-Norandrostenolone, 19-Nortestosterone, 4-Estren-17β-ol-3-one, Nadrolone, Nandrolone
  • 17-Hydroxy-estr-4-en-3-one