ChemicalBook > CAS DataBase List > Chloroacetamide

Chloroacetamide

Product Name
Chloroacetamide
CAS No.
79-07-2
Chemical Name
Chloroacetamide
Synonyms
2-CHLOROACETAMIDE;Chloracetamide;Microcide;KM 101;0/2/79;NSC 8408;mergalaf;Mergal AF;NSC 54286;usafdo-29
CBNumber
CB5691957
Molecular Formula
C2H4ClNO
Formula Weight
93.51
MOL File
79-07-2.mol
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Chloroacetamide Property

Melting point:
116-118 °C(lit.)
Boiling point:
224.5 °C
Density 
0.84
vapor pressure 
0.05 mm Hg ( 20 °C)
refractive index 
1.4480 (estimate)
Flash point:
170 °C
storage temp. 
Store below +30°C.
solubility 
methanol: soluble1g/10 mL
pka
14.69±0.40(Predicted)
form 
Crystalline Powder
color 
White
PH
3.8-4.1 (40g/l, H2O, 20℃)
Water Solubility 
Soluble in water(90g/L).
Merck 
14,2110
BRN 
878191
InChIKey
VXIVSQZSERGHQP-UHFFFAOYSA-N
LogP
-0.530
CAS DataBase Reference
79-07-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, 2-chloro-(79-07-2)
EPA Substance Registry System
Acetamide, 2-chloro- (79-07-2)
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Safety

Hazard Codes 
T
Risk Statements 
25-43-62
Safety Statements 
22-36/37-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
2
RTECS 
AB5075000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29241900
Hazardous Substances Data
79-07-2(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 138 mg/kg LD50 dermal Rat > 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H317May cause an allergic skin reaction

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C0267
Product name
2-Chloroacetamide
Purity
≥98%
Packaging
1kg
Price
$92.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02412
Product name
2-Chloroacetamide
Purity
for synthesis
Packaging
100g
Price
$27.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02412
Product name
2-Chloroacetamide
Purity
for synthesis
Packaging
1kg
Price
$104
Updated
2024/03/01
Sigma-Aldrich
Product number
8.02412
Product name
2-Chloroacetamide
Purity
for synthesis
Packaging
25kg
Price
$976
Updated
2024/03/01
Sigma-Aldrich
Product number
22790
Product name
2-Chloroacetamide
Purity
≥98.0% (HPLC)
Packaging
250g
Price
$35
Updated
2024/03/01
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Chloroacetamide Chemical Properties,Usage,Production

Description

Chloroacetamide is a preservative used in several applications such as in cutting metalwork fluids, in paints or in glues. It can induce contact dermatitis in hairdressers, or in shoemakers when used as a leather preservative.

Chemical Properties

white crystalline powder

Uses

2-Chloroacetamide is used as surface-active agent in home laundry, cleaning products & household formulated cleaners, other industrial uses, petroleum production, polymer processing.

Uses

A component of herbicidal mixtures of cellulose biosynthesis inhibitors with VLCFA inhibitors.

Uses

preservative in cosmetic and pharmaceutical creams, shampoos, bath lotions, etc.; preservative in glues, cooling fluids.

Flammability and Explosibility

Non flammable

Contact allergens

Chloroacetamide as a preservative is used in several applications as in cutting metalworking fluids, in paints or in glues. It can induce contact dermatitis in hairdressers or in shoemakers, being used as a leather preservative.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits very toxic Cland NOx. See also N-CHLOROACETAMIDE.

Synthesis

Chloroacetamide can be prepared from chloroacetyl chloride and dry ammonia gas and by treating ethyl chloroacetate or methyl chloroacetate with cold aqueous ammonia solutions in a 2-l. A round-bottomed flask fitted with a mechanical stirrer and surrounded by an ice-salt bath is placed 215 g. (1.75 moles) of ethyl chloroacetate. Vigorous stirring is started, and 200 cc. of chilled aqueous ammonia (sp. gr. 0.9) is added to the cold ester. The solution is stirred in the cold for about fifteen minutes, then another 200. A portion of aqueous ammonia is added, and the stirring is continued for about fifteen minutes. The mixture is then allowed to stand for thirty minutes, filtered with suction, and washed with two 25-cc. portions of cold water to remove ammonium chloride. The yield of air-dried material melting at 118–119℃ is 128–138 g. This product contains traces of ammonium chloride, which may be removed by crystallization from water. When 100 g. of crude product is recrystallized from 400 cc. of water, about 80 g. of product Chloroacetamide is obtained. The recrystallized product melts at 119–120°.

Purification Methods

Recrystallise the amide from acetone and dry it under vacuum over P2O5. [Beilstein 2 IV 490.]

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View Lastest Price from Chloroacetamide manufacturers

Hebei Longbang Technology Co., Ltd
Product
2-Chloroacetamide 79-07-2
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-29
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Chloroacetamide 79-07-2
Price
US $75.00-20.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-07
HebeiShuoshengImportandExportco.,Ltd
Product
Chloroacetamide 79-07-2
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08

79-07-2, ChloroacetamideRelated Search:


  • KM 101
  • NSC 54286
  • NSC 8408
  • 2-ChloroacetaMide >=98.0% (HPLC)
  • Piracetam Imp. B
  • chloroacetylamine
  • Mergal AF
  • mergalaf
  • Microcide
  • USAF do-29
  • usafdo-29
  • ALPHA-CHLOROACETAMIDE
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  • AKOS BBS-00003860
  • A-CHLORACETAMIDE
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  • 2-chloracetamide
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  • Piracetam Impurity 3 (2-Chloroacetamide)
  • 2-ChloroacetamideClCH2CONH2,Chloroacetamide, 2-Chloroethanamide
  • 79-07-2 Chloroacetamide
  • 2-Chloroacetamide [CAD
  • 0/2/79
  • 79-07-2
  • 1979-07-2
  • 1979-7-2
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  • 1979-07-02
  • 1979/7/2
  • ClCH2CONH2
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