NAC
- Product Name
- NAC
- CAS No.
- 154040-19-4
- Chemical Name
- NAC
- Synonyms
- NAC USP/EP/BP;61-95-α-Synuclein(human);α-Synuclein (61-95) (human);amyloid protein non-aβ component;AMYLOID PROTEIN NON-A BETA COMPONENT;EQVTNVGGAVVTGVTAVAQKTVEGAGSIIAAATGFV;Non-beta-Amyloid Component of Alzheimer’s Dise;NON-AB COMPONENT OF ALZHEIMER'S DISEASE AMYLOID;Non-Aβ Component of Alzheimer's Disease Amyloid;Amyloid Protein Non-Abeta Component >=80% (HPLC)
- CBNumber
- CB5697838
- Molecular Formula
- C141H235N39O49
- Formula Weight
- 3260.61
- MOL File
- 154040-19-4.mol
NAC Property
- Boiling point:
- 2937.7±65.0 °C(predicted)
- Density
- 1.296±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- storage temp.
- -20°C
- form
- solid
- Sequence
- H-Glu-Gln-Val-Thr-Asn-Val-Gly-Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala-Gln-Lys-Thr-Val-Glu-Gly-Ala-Gly-Ser-Ile-Ala-Ala-Ala-Thr-Gly-Phe-Val-OH
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A2835
- Product name
- Amyloid Protein Non-Aβ Component
- Purity
- ≥80% (HPLC)
- Packaging
- 0.1mg
- Price
- $203
- Updated
- 2025/07/31
- Product number
- orb372615
- Product name
- Non-Ab Component of Alzheimer's Disease Amyloid
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $644.3
- Updated
- 2021/12/16
- Product number
- orb372615
- Product name
- Non-Ab Component of Alzheimer's Disease Amyloid
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $1368.5
- Updated
- 2021/12/16
- Product number
- orb372615
- Product name
- Non-Ab Component of Alzheimer's Disease Amyloid
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $2046.8
- Updated
- 2021/12/16
NAC Chemical Properties,Usage,Production
Uses
α-Synuclein (61-95) (human) is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].
Biochem/physiol Actions
Found in the insoluble core of amyloid plaque; forms fibrils via a nucleation-dependent polymerization mechanism
IC 50
α-synuclein
References
[1] Tabner BJ, et al. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease. Free Radic Biol Med. 2002 Jun 1;32(11):1076-83. DOI:10.1016/s0891-5849(02)00801-8
[2] Emadi S, et al. Inhibiting aggregation of alpha-synuclein with human single chain antibody fragments. Biochemistry. 2004 Mar 16;43(10):2871-8.
NAC Preparation Products And Raw materials
Raw materials
Preparation Products
NAC Suppliers
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- United States
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