ChemicalBook > CAS DataBase List > 4-Fluoro-3-methylbenzonitrile

4-Fluoro-3-methylbenzonitrile

Product Name
4-Fluoro-3-methylbenzonitrile
CAS No.
185147-08-4
Chemical Name
4-Fluoro-3-methylbenzonitrile
Synonyms
4-FLUORO-3-METHYL;4-Fluoro-3-methylben;4-Fluoro-m-tolunitrile;5-CYANO-2-FLUOROTOLUENE;4-Fluoro-3-Methylbenzonitrle;3-METHYL-4-FLUOROBENZONITRILE;4-FLUORO-3-METHYLBENZONITRILE;4-Fluoro-3-methylbenzonitrile>Benzonitrile, 4-fluoro-3-methyl-;4-FLUORO-3-METHYLBENZONITRILE 99+%
CBNumber
CB5700255
Molecular Formula
C8H6FN
Formula Weight
135.14
MOL File
185147-08-4.mol
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4-Fluoro-3-methylbenzonitrile Property

Melting point:
53-56°C
Boiling point:
220.3±20.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
color 
White to Almost white
InChI
InChI=1S/C8H6FN/c1-6-4-7(5-10)2-3-8(6)9/h2-4H,1H3
InChIKey
ZMEAHKIIWJDJFT-UHFFFAOYSA-N
SMILES
C(#N)C1=CC=C(F)C(C)=C1
CAS DataBase Reference
185147-08-4(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
41
Safety Statements 
39
RIDADR 
UN3439
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0986
Product name
4-Fluoro-3-methylbenzonitrile
Purity
>98.0%(GC)
Packaging
5g
Price
$67
Updated
2025/07/31
TCI Chemical
Product number
F0986
Product name
4-Fluoro-3-methylbenzonitrile
Purity
>98.0%(GC)
Packaging
25g
Price
$285
Updated
2023/06/20
TRC
Product number
F597983
Product name
4-Fluoro-3-methylbenzonitrile
Packaging
250mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
021120
Product name
4-Fluoro-3-methylbenzonitrile
Purity
97%
Packaging
25g
Price
$24
Updated
2021/12/16
SynQuest Laboratories
Product number
3737-3-43
Product name
4-Fluoro-3-methylbenzonitrile
Purity
98%
Packaging
25g
Price
$25
Updated
2021/12/16
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4-Fluoro-3-methylbenzonitrile Chemical Properties,Usage,Production

Synthesis

41963-20-6

185147-08-4

The general procedure for the synthesis of 3-methyl-4-fluorobenzonitrile from 4-bromo-3-methylbenzonitrile was as follows: to an oven-dried, sealable reaction tube fitted with a stirrer were added sequentially 4-bromo-3-methylbenzonitrile (23.3 mg, 0.12 mmol), BrettPhos (6.4 mg, 0.012 mmol, 10 mol%), (COD)Pd( CH2TMS)2 (2.3 mg, 0.006 mmol, 5 mol%), AgF (22.8 mg, 0.18 mmol) and toluene (2 mL). The reaction tubes were sealed and removed from the glove box, wrapped in aluminum foil and placed in a preheated 130°C oil bath with continuous stirring for 18 hours. Upon completion of the reaction, the reaction tube was removed from the oil bath and cooled to room temperature. 4-Fluorotoluene (6.5 μL, 0.06 mmol, 0.5 eq.) and dodecane (27.3 μL, 0.12 mmol, 1 eq.) were added as internal standards. The reaction mixture was filtered through a glass filter and Celite pad to remove solids. The resulting clarified light yellow solution was analyzed for product yield by 19F NMR (282 MHz) and for conversion and reduction products by GC.

References

[1] Patent: US2011/15401, 2011, A1. Location in patent: Page/Page column 17
[2] Science, 2009, vol. 325, # 5948, p. 1661 - 1664

4-Fluoro-3-methylbenzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Fluoro-3-methylbenzonitrile Suppliers

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View Lastest Price from 4-Fluoro-3-methylbenzonitrile manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Fluoro-3-methylbenzonitrile 185147-08-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Fluoro-3-methylbenzonitrile 185147-08-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Career Henan Chemical Co
Product
4-Fluoro-3-methylbenzonitrile 185147-08-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

185147-08-4, 4-Fluoro-3-methylbenzonitrileRelated Search:

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