3-Amino-2-bromo-4,6-dimethylpyridine
- Product Name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- CAS No.
- 104829-98-3
- Chemical Name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- Synonyms
- AKOS BBS-00005796;IFLAB-BB F1371-0213;2-bromo-4,6-dimethyl-3-pyridinamine;2-bromo-4,6-dimethylpyridin-3-amine;5-Amino-2-bromo-4,6-dimethylpyridine;3-AMINO-2-BROMO-4,6-DIMETHYLPYRIDINE;3-Pyridinamine, 2-bromo-4,6-dimethyl-;2-BROMO-4,6-DIMETHYL-PYRIDIN-3-YLAMINE;3-Amino-2-bromo-4,6-dimethylpyridine97%;3-Amino-2-bromo-4,6-dimethylpyridine ,98%
- CBNumber
- CB5715480
- Molecular Formula
- C7H9BrN2
- Formula Weight
- 201.06
- MOL File
- 104829-98-3.mol
3-Amino-2-bromo-4,6-dimethylpyridine Property
- Melting point:
- 61-62 °C
- Boiling point:
- 304.8±37.0 °C(Predicted)
- Density
- 1.504±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 3.09±0.18(Predicted)
- color
- Light orange
- CAS DataBase Reference
- 104829-98-3(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- HS Code
- 2933399990
N-Bromosuccinimide Price
- Product number
- B997223
- Product name
- 2-Bromo-4,6-dimethylpyridin-3-amine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA03844
- Product name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- Packaging
- 1g
- Price
- $52.5
- Updated
- 2021/12/16
- Product number
- OR7028
- Product name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- Purity
- 97%
- Packaging
- 500mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- OR7028
- Product name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $32
- Updated
- 2021/12/16
- Product number
- 3H30-9-Z0
- Product name
- 3-Amino-2-bromo-4,6-dimethylpyridine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $36
- Updated
- 2021/12/16
3-Amino-2-bromo-4,6-dimethylpyridine Chemical Properties,Usage,Production
Synthesis
610261-09-1
104829-98-3
Bromine (2.8 g, 17.5 mmol) was added slowly dropwise to an aqueous solution (21 mL) of sodium hydroxide (2.1 g, 52.5 mmol) at -5 °C. Subsequently, 2-bromo-4,6-dimethylpyridine-3-carboxamide (3.19 g, 14 mmol) was added all at once. The reaction mixture was first stirred at 0 °C for 1 h, then warmed up to 70 °C and continued stirring for 1 h. The reaction was carried out at 0 °C for 1 h. The reaction mixture was then cooled to 70 °C. After completion of the reaction, the mixture was cooled to room temperature. Extraction was carried out with dichloromethane and the organic layer was washed with saturated brine and dried with anhydrous sodium sulfate. After filtration, the filtrate was concentrated and the residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate, 2:1) to afford the target product 3-amino-2-bromo-4,6-dimethylpyridine (2.8 g, 100% yield) as a light yellow solid.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 15, p. 5093 - 5097
[2] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 395 - 408,14
[3] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 395 - 408
[4] Organic Letters, 2008, vol. 10, # 21, p. 4895 - 4898
[5] Journal of Organic Chemistry, 2010, vol. 75, # 3, p. 716 - 725
3-Amino-2-bromo-4,6-dimethylpyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-2-bromo-4,6-dimethylpyridine Suppliers
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View Lastest Price from 3-Amino-2-bromo-4,6-dimethylpyridine manufacturers
- Product
- 3-Amino-2-bromo-4,6-dimethylpyridine 104829-98-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-27