6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

Product Name: 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
CAS No.: 38923-08-9
Chemical Name: 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Synonyms: Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate;ethyl 6-nitroH-imidazo[1,2-a]pyridine-2-carboxylate;6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER;6-nitroimidazo[1,2-α]pyridine-2-carboxylic acid ethyl ester;Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-nitro-, ethyl ester;Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate, CAS 38923-08-9;6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%
CBNumber: CB5738199
Molecular Formula: C10H9N3O4
Formula Weight: 235.2
MOL File: 38923-08-9.mol

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6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Property

Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 0.18±0.50(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C10H9N3O4/c1-2-17-10(14)8-6-12-5-7(13(15)16)3-4-9(12)11-8/h3-6H,2H2,1H3
InChIKey: XOXFLWMGZPJKAF-UHFFFAOYSA-N
SMILES: C12=NC(C(OCC)=O)=CN1C=C([N+]([O-])=O)C=C2

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0037532
Product name: Ethyl6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Packaging: 5g
Price: $135
Updated: 2021/12/16

Matrix Scientific

Product number: 056342
Product name: Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Purity: >95%
Packaging: 500mg
Price: $181
Updated: 2021/12/16

Matrix Scientific

Product number: 056342
Product name: Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Purity: >95%
Packaging: 1g
Price: $228
Updated: 2021/12/16

AK Scientific

Product number: W5941
Product name: Ethyl6-nitroimidazo[1,2-a]pyridine-2-carboxylate
Packaging: 25g
Price: $451
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0960341
Product name: 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER
Purity: 95.00%
Packaging: 1G
Price: $461
Updated: 2021/12/16

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6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

4214-76-0

70-23-5

38923-08-9

The reaction was carried out at reflux for 16 hours with 2-amino-5-nitropyridine (1.5 g, 10.80 mmol) and ethyl 3-bromopyruvate (1.6 mL, 13.00 mmol) dissolved in ethanol (15.0 mL). After completion of the reaction, the reaction mixture was filtered and a light yellow solid was collected. The filtrate was extracted with ethyl acetate and washed sequentially with saturated aqueous sodium bicarbonate and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by fast column chromatography (silica gel, n-hexane: ethyl acetate = 2:1) to afford ethyl 6-nitroimidazo[1,2-A]pyridine-2-carboxylate (2.3 g, 90% yield) as a yellow solid.LC/MS ESI(+): m/z 236 [M + H]+. 1H NMR (300 MHz, CDCl3) δ: 9.30 (s, 1H), 8.38 (s, 1H), 8.06 (d, 1H, J = 10.0 Hz), 7.84 (d, 1H, J = 10.4 Hz), 4.50 (q, 2H, J = 7.2 Hz), 1.46 (t, 3H, J = 7.2 Hz).

References

[1] Patent: WO2014/196793, 2014, A1. Location in patent: Page/Page column 64; 65
[2] Molecular Pharmaceutics, 2015, vol. 12, # 6, p. 1813 - 1835
[3] Patent: WO2015/185142, 2015, A1. Location in patent: Page/Page column 20
[4] Patent: WO2008/100423, 2008, A1. Location in patent: Page/Page column 111
[5] Patent: EP1657242, 2006, A1. Location in patent: Page/Page column 27

6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co

Product: 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 38923-08-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-02

38923-08-9, 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTERRelated Search:

6-Nitroimidazo[1,2-a]pyridine-2-carboxylic acid 6-Nitrooxidole 6-nitrothiazolo[4,5-b]pyridin-2-aMine 6-NITRO-ISOINDOLIN-1-ONE 6-NITROPYRIDINE-2-CARBOXYLIC ACID 6-NITROISOQUINOLINE 5-HYDROXY-2-NITROPYRIDINE 6-NITROQUINOXALINE 6-NITRO INDAZOLE-3-CARBOXALDEHYDE 6-nitrobenzo[d]isoxazol-3-amine Methyl 6-nitronicotinate 6-NITROIMIDAZO[1,2-A]PYRIDINE Ethyl 6-aminoimidazo[1,2-a]pyridine-2-carboxylate IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER 6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER Imidazo[1,2-a]pyridin-6-amine (9CI) 2-Methyl-6-nitroimidazo[1,2-a]pyridine 3-IODO-6-NITRO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER

6-nitroimidazo[1,2-α]pyridine-2-carboxylic acid ethyl ester

6-NITROIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID ETHYL ESTER, 95+%

Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate

Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-nitro-, ethyl ester

ethyl 6-nitroH-imidazo[1,2-a]pyridine-2-carboxylate

Ethyl 6-nitroimidazo[1,2-a]pyridine-2-carboxylate, CAS 38923-08-9

38923-08-9

Heterocycle-Pyridine series