4-Thiazolecarboxylic acid

Product Name: 4-Thiazolecarboxylic acid
CAS No.: 3973-08-8
Chemical Name: 4-Thiazolecarboxylic acid
Synonyms: THIAZOLE-4-CARBOXYLIC ACID;3973/8/8;NSC 195467;AKOS BB-9161;4-CARBOXYTHIAZOLE;TIMTEC-BB SBB010166;4-Carboxy-1,3-thiazole;4-THIAZOLECARBOXYLIC ACID;4-Thiazolecarboxylic acid 97%;1,3-THIAZOLE-4-CARBOXYLIC ACID
CBNumber: CB5769438
Molecular Formula: C4H3NO2S
Formula Weight: 129.14
MOL File: 3973-08-8.mol

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4-Thiazolecarboxylic acid Property

Melting point:: 195-199 °C (lit.)
Boiling point:: 191 °C
Density: 1.525±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 3.57±0.10(Predicted)
color: White to Off-White
λmax: 230nm(EtOH)(lit.)
InChI: InChI=1S/C4H3NO2S/c6-4(7)3-1-8-2-5-3/h1-2H,(H,6,7)
InChIKey: HMVYYTRDXNKRBQ-UHFFFAOYSA-N
SMILES: S1C=C(C(O)=O)N=C1
CAS DataBase Reference: 3973-08-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29341000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H317May cause an allergic skin reaction
Precautionary statements: P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 633658
Product name: 4-Thiazolecarboxylic acid
Purity: 97%
Packaging: 1g
Price: $22.61
Updated: 2025/07/31

Sigma-Aldrich

Product number: 633658
Product name: 4-Thiazolecarboxylic acid
Purity: 97%
Packaging: 5g
Price: $93.8
Updated: 2025/07/31

TCI Chemical

Product number: T2494
Product name: Thiazole-4-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $71
Updated: 2025/07/31

TCI Chemical

Product number: T2494
Product name: Thiazole-4-carboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $210
Updated: 2025/07/31

TRC

Product number: T344195
Product name: 4-Thiazolecarboxylic acid
Packaging: 10g
Price: $950
Updated: 2021/12/16

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4-Thiazolecarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Pale yellow to white solid

Uses

4-Thiazolecarboxylic Acid (cas# 3973-08-8) is a compound useful in organic synthesis.

Synthesis

693-95-8

3973-08-8

The general procedure for the synthesis of thiazole-4-carboxylic acid from 4-methylthiazole was as follows: 4-methylthiazole (19.8 g, 0.2 mol), 200 mL of water, and potassium permanganate (173.8 g, 1.1 mol) were added to a 500 mL three-necked flask, which was heated to 55 °C with stirring and kept for 22 hours. After completion of the reaction, the reaction mixture was cooled and filtered. The filter cake (mainly composed of manganese dioxide) was washed with hot water at 50°C. The filtrate was adjusted to pH 3 with dilute hydrochloric acid, precipitated as a solid and filtered. The filter cake was washed with a small amount of water and dried to give 18.1 g of thiazole-4-carboxylic acid in 70.2% yield, melting point 196-198 °C.

References

[1] Angewandte Chemie, 1992, vol. 104, # 6, p. 748 - 749
[2] Patent: CN104557902, 2018, B. Location in patent: Paragraph 0063; 0076; 0081; 0088; 0089; 0102

4-Thiazolecarboxylic acid Preparation Products And Raw materials

Raw materials

THIOFORMAMIDE Pyruvic acid Methyl Bromopyruvate METHYL 4-THIAZOLECARBOXYLATE 1,2-Dimethoxyethane

Preparation Products

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Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $9.90/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-12-03

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

Career Henan Chemical Co

Product: 4-Thiazolecarboxylic acid 3973-08-8
Price: US $8.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-15

3973-08-8, 4-Thiazolecarboxylic acidRelated Search:

2-(2-Aminothiazol-4-yl)glyoxylic acid 2-Mercaptobenzothiazole Thiazole Benzothiazole 2,2'-Dithiobis(benzothiazole) Fosthiazate Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) 5-THIAZOLECARBOXYLIC ACID Thiazole-4-carboxaldehyde THIAZOLE-2-CARBOXYLIC ACID THIAZOLE-4-CARBOXAMIDE 4H-THIENO[3,2-B]PYRROLE-5-CARBOXYLIC ACID Ethyl thiazole-5-carboxylate 2-THIAZOLE-4-BORONIC ACID THIAZOLO[5,4-B]PYRIDIN-2-AMINE Ethyl thiazole-2-carboxylate thiazol-4-ylboronic acid pinacol ester C-THIAZOL-4-YL-METHYLAMINE HYDROCHLORIDE

4-Thiazolecarboxylic acid 3973-8-8

1,3-Thiazole-4-Carboxylic Acid 3973-8-8

1,3-thiazole-4-carboxylic acid(SALTDATA: FREE)

4-Carboxy-1,3-thiazole

NSC 195467

4-Thiazolecarboxylic acid 97%

4-Thiazolecarboxylic Acid, 97+%

3973/8/8

1,3-THIAZOLE-4-CARBOXYLIC ACID

AKOS BB-9161

4-CARBOXYTHIAZOLE

4-THIAZOLECARBOXYLIC ACID

TIMTEC-BB SBB010166

THIAZOLE-4-CARBOXYLIC ACID

3973-08-8

3937-08-8

3973-08-6

3973-8-8

3973/8/8

757-36-9

C4H3NO2S

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