ChemicalBook > CAS DataBase List > 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE

Product Name: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE
CAS No.: 171366-19-1
Chemical Name: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE
Synonyms: 2-Fluoro-4-iodo-3-pyridinemethanol;3-Pyridinemethanol,2-fluoro-4-iodo-;(2-Fluoro-4-iodopyridin-3-yl)Methanol;2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE;2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE ISO 9001：2015 REACH
CBNumber: CB5781731
Molecular Formula: C6H5FINO
Formula Weight: 253.01
MOL File: 171366-19-1.mol

Less

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE Property

Boiling point:: 330.4±37.0 °C(Predicted)
Density: 2.061
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 12.27±0.10(Predicted)
Appearance: Light yellow to yellow Solid

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Frontier Specialty Chemicals

Product number: Y15328
Product name: 2-Fluoro-3-(hydroxymethyl)-4-iodopyridine
Purity: 98%
Packaging: 1g
Price: $38
Updated: 2021/12/16

Matrix Scientific

Product number: 097318
Product name: (2-Fluoro-4-iodopyridin-3-yl)methanol
Purity: 95+%
Packaging: 250mg
Price: $265
Updated: 2021/12/16

AK Scientific

Product number: J95317
Product name: 2-Fluoro-3-(hydroxymethyl)-4-iodopyridine
Packaging: 1g
Price: $312
Updated: 2021/12/16

Matrix Scientific

Product number: 097318
Product name: (2-Fluoro-4-iodopyridin-3-yl)methanol
Purity: 95+%
Packaging: 1g
Price: $588
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0070531
Product name: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE
Purity: 95.00%
Packaging: 1G
Price: $1139.99
Updated: 2021/12/16

Less

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE Chemical Properties,Usage,Production

Synthesis

113975-22-7

109-94-4

171366-19-1

Example 1 Synthesis of 2-fluoro-4-iodo-3-(hydroxymethyl)pyridine: A solution of LDA was prepared by reacting diisopropylamine (0.63 mL, 4.49 mmol) with n-butyllithium (4.49 mmol) in tetrahydrofuran (THF, 10 mL) at -78 °C and under nitrogen protection. To this solution, a solution of 2-fluoro-3-iodopyridine (1 g, 4.48 mmol) dissolved in THF (2 mL) was added dropwise and stirred for 1 hour at -78 °C. Subsequently, ethyl formate (1.1 mL, 13.6 mmol) was added at the same temperature and stirring was continued for 30 min. The reaction mixture was quenched with saturated sodium bicarbonate solution and slowly warmed to room temperature. Sodium borohydride (0.34 g, 8.99 mmol) was slowly added to the mixture and stirred for 30 minutes before extracting with ethyl acetate. The organic phases were combined, washed with brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by radial preparative thin layer chromatography (silica gel, hexanes, 10% ethyl acetate/hexanes, 20% ethyl acetate/hexanes) to give 708 mg (62% yield) of the target product as a white solid with a melting point of 69°-70 °C. Elemental analysis (C6H5FINO): calculated values: C 28.48, H 1.99, N 5.54; measured values: C 28.55, H 1.94, N 5.48. IR spectrum (KBr, cm^-1): 3336, 1584, 1541, 1446, 1401, 1264, 1218, 1003, 870, 833, 803. 761, 577. 1H NMR (CDCl3): δ 7.79-7.82 (d, 1H, J = 5 Hz), 7.66-7.68 (d, 1H, J = 5 Hz), 4.82-4.86 (d, 2H, J = 7 Hz), 1.99-2.04 (t, 1H, J = 14 Hz). 13C NMR (CDCl3): δ 162.29, 159.05, 147.30, 147.09, 132.79, 132.73, 126.14, 125.73, 114.21, 62.24.

References

[1] Patent: US5496952, 1996, A

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE Suppliers

China 55 Germany 2 India 2 United Kingdom 1 United States 10 Global 70

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 86(512)5235 8471 17715136450
Fax: 86(512)5235 6881
Email: sales@shiyabiopharm.com
Country: China
ProdList: 4169
Advantage: 58

Hebei Summedchem Co.,Ltd

Tel: 0319-5801333-8008 15630992918
Email: sales@summedchem.com
Country: China
ProdList: 965
Advantage: 58

Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4894
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Hebei Huaxing Chemical Co., Ltd

Tel: 0319-6931777 13930968617
Fax: +86-319-6931577
Email: 630669494@qq.com
Country: China
ProdList: 1021
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Neostar United (Changzhou) Industrial Co., Ltd.

Tel: +86-0519-85551759 +8613506123987
Fax: +0086-519-85557389
Email: marketing1@neostarunited.com
Country: China
ProdList: 8830
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9991
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Mainchem Co., Ltd.

Tel: --
Fax: --
Email: sarah@mainchem.com
Country: China
ProdList: 6547
Advantage: 58

Henan Lavoisier Chemical Products Co. Ltd

Tel: 0371-63682289 18625781376
Fax: 18625781376
Email: jacschem@163.com
Country: China
ProdList: 4965
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Weihai Huaixin Biotechnology Co., Ltd

Tel: 15662379806
Email: 845423637@qq.com
Country: China
ProdList: 1609
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Beijing Stronger Science Co., Ltd.

Tel: 0531-88924771 15614660963
Email: elsa.hang@strongerscience.com
Country: China
ProdList: 10623
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Tianjin Xinghan Biotechnology Co., Ltd

Tel: 13230698506 18698089028
Email: 1725517238@qq.com
Country: China
ProdList: 5009
Advantage: 58

Suzhou Victorypharm Co.,Ltd.

Tel: 512-68242903 13916956214
Email: sales@victory-pharm.com
Country: China
ProdList: 1551
Advantage: 58

Qingzhou dafeng import and export Co. LTD

Tel: 16773308882
Email: 927608786@qq.com
Country: China
ProdList: 3051
Advantage: 58

Heze Aiding Pharmaceutical Co., Ltd

Tel: 17661365138
Email: 2845578351@qq.com
Country: China
ProdList: 7115
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-029-81123119 17391733320
Email: 1021@dideu.com
Country: China
ProdList: 9995
Advantage: 58

Anhui Henuo Biotechnology Co., Ltd

Tel: 18455579438
Country: China
ProdList: 16684
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Liaocheng Lebote Biopharmaceutical Technology Co., Ltd

Tel: 0635-893290 18663513896;
Email: 28698871@qq.com
Country: China
ProdList: 8022
Advantage: 58

Jining Yize Pharmaceutical Technology Co., Ltd

Tel: 15192473210
Email: 302633902@qq.com
Country: China
ProdList: 4480
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 19355912709
Email: 690231469@qq.com
Country: China
ProdList: 7593
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

SuZhou ShiYa Biopharmaceuticals, Inc.

Tel: 17715136450
Email: 2439673774@qq.com
Country: China
ProdList: 15647
Advantage: 58

Wuxi Likang Biomedical Technology Co., Ltd

Tel: 15250805028 15250805028;
Email: 649163353@qq.com
Country: China
ProdList: 8001
Advantage: 58

ANHUI BYERSEN BIOTECH CO. LTD

Tel: +86-15385096007 +86-17755058861
Email: amy@byersenchemical.com
Country: China
ProdList: 10000
Advantage: 58

XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.

Tel: +8618950047208
Email: ellena@amitychem.com
Country: China
ProdList: 43416
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Tianjin Xinghan Biotechnology Co., Ltd

Tel: +8618698089028
Email: 1725517238@qq.com
Country: China
ProdList: 2479
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49941
Advantage: 58

PT CHEM GROUP LIMITED

Tel: +86-85511178;
Email: peter68@ptchemgroup.com
Country: China
ProdList: 35425
Advantage: 58

Less

View Lastest Price from 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE 171366-19-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

Career Henan Chemical Co

Product: 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE 171366-19-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kg
Release date: 2020-01-13

171366-19-1, 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINERelated Search:

4-IODO-PYRIDIN-3-OL 4-Iodopyridine 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE 2-FLUORO-4-IODO-3-PICOLINE 2-Fluoro-3-iodopyridine 2-Fluoro-3-methylpyridine 2-FLUORO-4-IODONICOTINIC ACID 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 4-Iodo-3-methylpyridine 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE

(2-Fluoro-4-iodopyridin-3-yl)Methanol

3-Pyridinemethanol,2-fluoro-4-iodo-

2-Fluoro-4-iodo-3-pyridinemethanol

2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE ISO 9001：2015 REACH

171366-19-1

6H5FINO

Pyridines

Boronic Acid

Pyridine