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canadine

Product Name
canadine
CAS No.
5096-57-1
Chemical Name
canadine
Synonyms
C03329;(-)-Canadine;(S)-Canadine;(S)-Tetrahydroberberine;(13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-
CBNumber
CB5939134
Molecular Formula
C20H21NO4
Formula Weight
339.39
MOL File
5096-57-1.mol
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canadine Property

Melting point:
135°
alpha 
D22 -308°; -317° (c = 0.28; 0.4, both in methanol)
Boiling point:
475.36°C (rough estimate)
Density 
1.2270 (rough estimate)
refractive index 
1.6000 (estimate)
storage temp. 
Refrigerator
solubility 
Chloroform, Ethyl Acetate (Slightly), Methanol (Very Slightly, Heated)
form 
Solid
pka
6.53±0.20(Predicted)
color 
Pale Yellow to Light Yellow
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Safety

RIDADR 
1544
HazardClass 
6.1(b)
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C175180
Product name
(S)-(-)-Canadine
Packaging
250mg
Price
$1455
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
55371
Product name
(S)-(-)-Canadine
Packaging
250mg
Price
$2200
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0002233
Product name
L-CANADINE
Purity
95.00%
Packaging
5MG
Price
$498.05
Updated
2021/12/16
Crysdot
Product number
CD32001189
Product name
Canadine
Purity
95+%
Packaging
5mg
Price
$640
Updated
2021/12/16
Arctom
Product number
CFN98810
Product name
Canadine
Purity
≥98%
Packaging
5mg
Price
$463
Updated
2021/12/16
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canadine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

(S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.

Definition

ChEBI: (S)-canadine is the (S)-enantiomer of canadine. It has a role as a plant metabolite. It is functionally related to a (S)-nandinine. It is an enantiomer of a (R)-canadine.

target

P450 (e.g. CYP17)

canadine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from canadine manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Canadine 5096-57-1
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-12-16

5096-57-1, canadine Related Search:


  • (13As)-5,8,13,13A-tetrahydro-9,10-dimethoxy-6H-benzo[G]-1,3-benzodioxolo[5,6-A]quinolizine
  • (S)-Canadine
  • (S)-Tetrahydroberberine
  • C03329
  • 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13aS)-
  • (-)-Canadine
  • 5096-57-1