5-Iodo-2-pyrimidone
- Product Name
- 5-Iodo-2-pyrimidone
- CAS No.
- 79387-69-2
- Chemical Name
- 5-Iodo-2-pyrimidone
- Synonyms
- 5-Iodo-2-pyrimidone;5-Iodopyrimidin-2(1H);5-iodo-1H-pyrimidin-2-one;5-IodopyriMidin-2(1H)-one;2-Hydroxy-5-Iodopyrimidine;2(1H)-Pyrimidinone, 5-iodo-;5-Iodo-2(1H)-pyrimidinone, 97+%;5-Iodo-2-pyrimidone ISO 9001：2015 REACH
- CBNumber
- CB5947719
- Molecular Formula
- C4H3IN2O
- Formula Weight
- 221.98
- MOL File
- 79387-69-2.mol
5-Iodo-2-pyrimidone Property
- Density
- 2.40±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 7.86±0.10(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C4H3IN2O/c5-3-1-6-4(8)7-2-3/h1-2H,(H,6,7,8)
- InChIKey
- PVHCYDBPRLPQMP-UHFFFAOYSA-N
- SMILES
- C1(=O)NC=C(I)C=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- J94974
- Product name
- 2-Hydroxy-5-iodopyrimidine
- Packaging
- 1g
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 118880
- Product name
- 5-Iodopyrimidin-2(1H)-one
- Purity
- 95+%
- Packaging
- 1g
- Price
- $172
- Updated
- 2021/12/16
- Product number
- J94974
- Product name
- 2-Hydroxy-5-iodopyrimidine
- Packaging
- 5g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- HCH0118915
- Product name
- 2-HYDROXY-5-IODOPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.78
- Updated
- 2021/12/16
- Product number
- 118880
- Product name
- 5-Iodopyrimidin-2(1H)-one
- Purity
- 95+%
- Packaging
- 5g
- Price
- $532
- Updated
- 2021/12/16
5-Iodo-2-pyrimidone Chemical Properties,Usage,Production
Synthesis
557-01-7
79387-69-2
The general procedure for the synthesis of 5-iodo-2-pyrimidinone from 2(1H)-pyrimidinone is as follows: in Example 3, 2-pyrimidinone (6 g, 62.44 mmol) and N-iodosuccinimide (14.7 g, 65.3 mmol) were dissolved in anhydrous DMF (30 ml), and stirred for 48 hr. at room temperature away from light and moisture. After completion of the reaction, the reaction mixture was slowly poured into ether (50 ml) under stirring and the supernatant was removed by decantation. The precipitate was collected by filtration and washed sequentially with acetone and methanol until the filtrate showed light yellow color. After drying under vacuum, the yellow granular product 5-iodo-2(1H)-pyrimidinone was obtained.TLC and spectral analysis showed high purity of the product, but elemental analysis indicated the presence of trace DMF contamination. The final yield was 11.35 g with 77.5% yield.
References
[1] Journal of Medicinal Chemistry, 1985, vol. 28, # 7, p. 904 - 910
[2] Patent: US4895937, 1990, A
[3] Patent: US4782142, 1988, A
5-Iodo-2-pyrimidone Preparation Products And Raw materials
Raw materials
Preparation Products
5-Iodo-2-pyrimidone Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 5-Iodo-2-pyrimidone manufacturers
- Product
- 5-Iodopyrimidin-2-ol 79387-69-2
- Price
- US $1.10-9.90/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-14
- Product
- 5-Iodo-2-pyrimidone 79387-69-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-06