ChemicalBook > CAS DataBase List > Vilobelimab
Vilobelimab
- Product Name
- Vilobelimab
- CAS No.
- 2250440-41-4
- Chemical Name
- Vilobelimab
- Synonyms
- Vilobelimab;Research Grade Vilobelimab;Vilobelimab (anti-Complement C5);Research Grade Vilobelimab (DHB90008)
- CBNumber
- CB610616956
- Formula Weight
- 0
- MOL File
- Mol file
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Vilobelimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Vilobelimab Chemical Properties,Usage,Production
Uses
Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc[1].
References
[1] Michael Bauer, et al. Efficacy and Safety of Vilobelimab (IFX-1), a Novel Monoclonal Anti-C5a Antibody, in Patients With Early Severe Sepsis or Septic Shock-A Randomized, Placebo-Controlled, Double-Blind, Multicenter, Phase IIa Trial (SCIENS Study). Crit Care Explor. 2021 Nov 17;3(11):e0577. DOI:10.1097/CCE.0000000000000577
Vilobelimab Preparation Products And Raw materials
Raw materials
Preparation Products
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Vilobelimab Suppliers
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