1-METHYLURIC ACID
- Product Name
- 1-METHYLURIC ACID
- CAS No.
- 708-79-2
- Chemical Name
- 1-METHYLURIC ACID
- Synonyms
- 1-U;1MUA;1-METHYLURIC ACID;1-Methyluric acid ,98%;Theophylline Impurity 17;1-METHYLURIC ACID USP/EP/BP;1-METHYL-2,6,8-TRIHYDROXYPURINE;1-Methyl-1H-purine-2,6,8(3H,7H,9H)-trione;1-methyl-7,9-dihydro-3H-purine-2,6,8-trione;7,9-dihydro-1-methyl-1H-purine-2,6,8(3H)-trione
- CBNumber
- CB6107257
- Molecular Formula
- C6H6N4O3
- Formula Weight
- 182.14
- MOL File
- 708-79-2.mol
1-METHYLURIC ACID Property
- Melting point:
- >325°C
- Boiling point:
- 315.51°C (rough estimate)
- Density
- 1.5283 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- Refrigerator
- solubility
- Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated, Sonicated)
- form
- Solid
- pka
- 5.60±0.50(Predicted)
- color
- Pale Yellow to Pale Brown
- Water Solubility
- 1.585g/L(temperature not stated)
- BRN
- 195190
Safety
- WGK Germany
- 3
- HS Code
- 29242990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M6885
- Product name
- 1-Methyluric acid
- Packaging
- 50mg
- Price
- $146
- Updated
- 2023/01/07
- Product number
- M6885
- Product name
- 1-Methyluric acid
- Packaging
- 100mg
- Price
- $259
- Updated
- 2023/01/07
- Product number
- M338180
- Product name
- 1-Methyluric acid
- Packaging
- 25mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 017570
- Product name
- 1-Methyluric Acid
- Packaging
- 10mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- 281677
- Product name
- 1-Methyluric acid
- Packaging
- 25mg
- Price
- $375
- Updated
- 2021/12/16
1-METHYLURIC ACID Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Uses
1-Methyluric acid, a metabolite of Theophylline, has been used:
for the determination of uric acid in stool samples by liquid chromatography and tandem mass spectrometry
in turbidimetric assay of synthetic urine samples
as a substrate for CYP1A2(cytochrome P450 family 1 subfamily A member 2) assay
Definition
ChEBI: An oxopurine that is 7,9-dihydro-1H-purine-2,6,8(3H)-trione substituted by a methyl group at N-1. It is one of the metabolites of caffeine found in human urine.
Biochem/physiol Actions
1-Methyluric acid (1-U) is a major metabolite of caffeine and theophylline with antioxidant activity that protects molecules such as low density lipoproteins (LDL) from oxidative modifications. 1-Methyluric acid may be used in studies aimed at differentiating the activities of caffeine and theophylline metabolites.
Purification Methods
Recrystallise it from H2O. Its solubility at 17.5o is 1g in 353mL of H2O. [Bergmann & Dikstein J Am Chem Soc 77 691 1955.] It has UV: max at 231 and 283nm (pH 3), and 217.5 and 292.5nm (pH >12) [Johnson Biochem J 5 133 1952]. [Beilstein 26 II 299, 26 III/IV 2621.]
1-METHYLURIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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