ChemicalBook > CAS DataBase List > Theaflavin

Theaflavin

Product Name: Theaflavin
CAS No.: 4670-05-7
Chemical Name: Theaflavin
Synonyms: Theaflavins;THEAFLAVINE;6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one;THEAFLAVIN;Theaflavin 1;6-trihydroxy-;THEAFLAVIN USP/EP/BP;hot selling Theaflavine;Theaflavin, 10 mM in DMSO;Theaflavin, froM green tea
CBNumber: CB6110367
Molecular Formula: C29H24O12
Formula Weight: 564.49
MOL File: 4670-05-7.mol

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Theaflavin Property

Melting point:: 237-240 °C (decomp)(Solv: water (7732-18-5))
Boiling point:: 1079.6±65.0 °C(Predicted)
Density: 1.777±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 6.65±0.20(Predicted)
color: Red to Very Dark Red
InChIKey: IPMYMEWFZKHGAX-ZKSIBHASSA-N
SMILES: C12=C(O)C(O)=CC([C@H]3OC4=CC(O)=CC(O)=C4C[C@H]3O)=C1C=C([C@H]1OC3=CC(O)=CC(O)=C3C[C@H]1O)C=C(O)C2=O
LogP: 1.165 (est)

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Safety

Safety Statements: 24/25
WGK Germany: 3
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL83341
Product name: Theaflavin
Purity: phyproof? Reference Substance
Packaging: 10mg
Price: $549
Updated: 2025/07/31

Sigma-Aldrich

Product number: 55016
Product name: Theaflavin
Purity: analytical standard
Packaging: 1mg
Price: $713
Updated: 2025/07/31

TCI Chemical

Product number: T3962
Product name: Theaflavin
Packaging: 5MG
Price: $130
Updated: 2025/07/31

TCI Chemical

Product number: T3962
Product name: Theaflavin
Packaging: 25MG
Price: $389
Updated: 2025/07/31

Cayman Chemical

Product number: 25129
Product name: Theaflavin
Purity: ≥98%
Packaging: 1mg
Price: $36
Updated: 2024/03/01

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Theaflavin Chemical Properties,Usage,Production

Description

Theaflavins are a group of polyphenol pigments found in both black and oolong teas. They are obtained by the oxidation and dimerization of green tea catechins during the manufacture of black tea and oolong tea. Theaflavins contribute to the characteristic bright orange-red color of black tea. Theaflavins include theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate and theaflavin-3,3'-digallate.
Theaflavins are used to manage cholesterol and used to support the heart and digestive system. They could be used as protective agents against cardiovascular disease and cancer. It is also believed that they have a wide range of other pharmaceutical benefits, including antihypertensive, antioxidative and hypolipidemic activities. It is suggested that theaflavins have a potential to be developed as a safe and affordable topical microbicide for preventing sexual transmission of HIV.

Chemical Properties

red to brown powder

Uses

Theaflavin is a polyphenolic compound found in black tea. Theaflavin derivatives show anti-HIV-1 activity by targeting gp41. Theaflavin is a potent inhibitor of amyloid-β (Aβ) and α-synuclein (αS) fibrillogenesis. Theaflavin also shows potent anti-tumor and and antoxidant activities.

Definition

ChEBI: Theaflavin is a biflavonoid that is 3,4,5-trihydroxybenzocyclohepten-6-one which is substituted at positions 1 and 8 by (2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl groups. It is the main red pigment in black tea. It has a role as an antioxidant, a chelator, a plant metabolite, a radiation protective agent and an antibacterial agent. It is a polyphenol and a biflavonoid.

benefits

Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antineoplastic, antioxidant, anticancer, anti-inflammatory, cholesterol lowering and antiviral properties.

Biological Activity

Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.

References

[1] Lai Kwok Leung, Yalun Su, Ruoyun Chen, Zesheng Zhang, Yu Huang, Zhen-Yu Chen (2001) Theaflavins in Black Tea and Catechins in Green Tea Are Equally Effective, J. Nutr., 131, 2248-2251
[2] Yang J, Li L, Tan S, Jin H, Qiu J, Mao Q, Li R, Xia C, Jiang ZH, Jiang S, Liu S (2012) A Natural Theaflavins Preparation Inhibits HIV-1 Infection by Targeting the Entry Step: Potential Applications for Preventing HIV-1 Infection, Fitoterapia, 83, 348-355
[3] http://www.xtend-life.com/information/ingredients/theaflavins

Theaflavin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Theaflavin manufacturers

BINBO BIOLOGICAL CO.,LTD

Product: Theaflavin 4670-05-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 20% 22% 40% 60% 90%
Supply Ability: 1000 kg
Release date: 2025-11-27

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Theaflavin 4670-05-7
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-11

BINBO BIOLOGICAL CO.,LTD

Product: Theaflavin 4670-05-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 20% 40% 90%
Supply Ability: 1000 kg
Release date: 2024-04-23

4670-05-7, TheaflavinRelated Search:

CHLOROPHYLL Lycopene Tea polyphenol Folic acid CYANIDIN CHLORIDE Curcumin Canthaxanthin Tannic acid THEAFLAVIN 3'-O-GALLATE THEAFLAVINE(P) Theaflavin Theaflavin 3,3′-digallate THEAFLAVIN 3'-GALLATE THEAFLAVIN 3-O-GALLATE BENZOCYCLOHEPTATRIENE THEAFLAVIN 3-GALLATE THEAFLAVIN (BLACK TEA) STANDARDS KIT

THEAFLAVIN

THEAFLAVINE

1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-5h-benzocyclohepten-5-one

5h-benzocyclohepten-5-one,1,8-bis(3-alpha,5,7-trihydroxy-2-alpha-chromanyl)-3,

6-trihydroxy-

Theaflavins

6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one

3,4,6-Trihydroxy-1,8-bis(3,4-dihydro-3α,5,7-trihydroxy-2H-1-benzopyran-2α-yl)-5H-benzocycloheptene-5-one

3,4,6-Trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]-5H-benzocycloheptene-5-one

3,4,6-Trihydroxy-1,8-bis[[(2R)-3,4-dihydro-3α,5,7-trihydroxy-2H-1-benzopyran]-2α-yl]-5H-benzocyclohepten-5-one

3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]benzo[7]annulen-6-one

3,4,5-trihydroxy-1,8-bis[(2R,3R)-3,5,7-trihydroxychroman-2-yl]benzocyclohepten-6-one

[2R-[2α(2R*,3R*),3α]]-1,8-Bis(3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl)-3,4,6-trihydroxy-5H-benzocyclohepten-5-one

1,8-Bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-5H-benzocyclohepten-5-one

3,4,6-Trihydroxy-1,8-bis(3α,5,7-trihydroxy-2α-chroManyl)-5H-benzocyclohepten-5-one

Theaflavin 1

Theaflavin, froM green tea

5H-Benzocyclohepten-5-one,1,8-bis[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-3,4,6-trihydroxy-

Theaflavin, 98%, from green tea

3,4,6-Trihydroxy-1,8-bis((2R,3R)-3,5,7-trihydroxychroman-2-yl)-5H-benzo[7]annulen-5-one

hot selling Theaflavine

THEAFLAVIN USP/EP/BP

5H-Benzocyclohepten-5-one, 1,8-bis[(2R,3R)-3,4-dihydro-3,5,7...

TheaflavinQ: What is Theaflavin Q: What is the CAS Number of Theaflavin Q: What is the storage condition of Theaflavin Q: What are the applications of Theaflavin

Theaflavin, 10 mM in DMSO

4670-05-7

4670-''5-7

C29H24O12

C29H24O9

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