Theaflavin
- Product Name
- Theaflavin
- CAS No.
- 4670-05-7
- Chemical Name
- Theaflavin
- Synonyms
- Theaflavins;THEAFLAVINE;6,8,9-trihydroxy-3,11-bis[(2S,3R)-3,5,7-trihydroxychroman-2-yl]bicyclo[5.4.0]undeca-1,3,6,8,10-pentaen-5-one;THEAFLAVIN;Theaflavin 1;6-trihydroxy-;THEAFLAVIN USP/EP/BP;hot selling Theaflavine;Theaflavin, froM green tea;Theaflavin, 98%, from green tea
- CBNumber
- CB6110367
- Molecular Formula
- C29H24O12
- Formula Weight
- 564.49
- MOL File
- 4670-05-7.mol
Theaflavin Property
- Melting point:
- 237-240 °C (decomp)(Solv: water (7732-18-5))
- Boiling point:
- 1079.6±65.0 °C(Predicted)
- Density
- 1.777±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 6.65±0.20(Predicted)
- color
- Red to Very Dark Red
- LogP
- 1.165 (est)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PHL83341
- Product name
- Theaflavin
- Purity
- phyproof? Reference Substance
- Packaging
- 10mg
- Price
- $514
- Updated
- 2024/03/01
- Product number
- 55016
- Product name
- Theaflavin
- Purity
- analytical standard
- Packaging
- 1mg
- Price
- $757
- Updated
- 2024/03/01
- Product number
- 25129
- Product name
- Theaflavin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $36
- Updated
- 2024/03/01
- Product number
- 25129
- Product name
- Theaflavin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
- Product number
- 25129
- Product name
- Theaflavin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $239
- Updated
- 2024/03/01
Theaflavin Chemical Properties,Usage,Production
Description
Theaflavins are a group of polyphenol pigments found in both black and oolong teas. They are obtained by the oxidation and dimerization of green tea catechins during the manufacture of black tea and oolong tea. Theaflavins contribute to the characteristic bright orange-red color of black tea. Theaflavins include theaflavin, theaflavin-3-gallate, theaflavin-3'-gallate and theaflavin-3,3'-digallate.
Theaflavins are used to manage cholesterol and used to support the heart and digestive system. They could be used as protective agents against cardiovascular disease and cancer. It is also believed that they have a wide range of other pharmaceutical benefits, including antihypertensive, antioxidative and hypolipidemic activities. It is suggested that theaflavins have a potential to be developed as a safe and affordable topical microbicide for preventing sexual transmission of HIV.
Chemical Properties
red to brown powder
Uses
Theaflavin is a polyphenolic compound found in black tea. Theaflavin derivatives show anti-HIV-1 activity by targeting gp41. Theaflavin is a potent inhibitor of amyloid-β (Aβ) and α-synuclein (αS) fibrillogenesis. Theaflavin also shows potent anti-tumor and and antoxidant activities.
Definition
ChEBI: Theaflavin is a biflavonoid that is 3,4,5-trihydroxybenzocyclohepten-6-one which is substituted at positions 1 and 8 by (2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl groups. It is the main red pigment in black tea. It has a role as an antioxidant, a chelator, a plant metabolite, a radiation protective agent and an antibacterial agent. It is a polyphenol and a biflavonoid.
benefits
Theaflavin is a polyphenolic flavonoid that has been found in black tea and has diverse biological activities, including antineoplastic, antioxidant, anticancer, anti-inflammatory, cholesterol lowering and antiviral properties.
Biological Activity
Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase.
References
[1] Lai Kwok Leung, Yalun Su, Ruoyun Chen, Zesheng Zhang, Yu Huang, Zhen-Yu Chen (2001) Theaflavins in Black Tea and Catechins in Green Tea Are Equally Effective, J. Nutr., 131, 2248-2251
[2] Yang J, Li L, Tan S, Jin H, Qiu J, Mao Q, Li R, Xia C, Jiang ZH, Jiang S, Liu S (2012) A Natural Theaflavins Preparation Inhibits HIV-1 Infection by Targeting the Entry Step: Potential Applications for Preventing HIV-1 Infection, Fitoterapia, 83, 348-355
[3] http://www.xtend-life.com/information/ingredients/theaflavins
Theaflavin Preparation Products And Raw materials
Raw materials
Preparation Products
Theaflavin Suppliers
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View Lastest Price from Theaflavin manufacturers
- Product
- Theaflavin 4670-05-7
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-12-11
- Product
- Theaflavin 4670-05-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 20% 40% 90%
- Supply Ability
- 1000 kg
- Release date
- 2024-04-23
- Product
- Theaflavin 4670-05-7
- Price
- US $0.00/mg
- Min. Order
- 20mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-22