ChemicalBook > CAS DataBase List > 2-Bromomethylquinoline

2-Bromomethylquinoline

Product Name
2-Bromomethylquinoline
CAS No.
5632-15-5
Chemical Name
2-Bromomethylquinoline
Synonyms
α-BroMoquinaldine;2-bromothylquinoline;2-Bromomethylquinoline;2-(Bromomethyl)quinoline;2-QuinolinylMethyl broMide;Quinolin-2-ylmethylbromide;Quinoline, 2-(bromomethyl)-;2-(Bromomethyl)-1-azanaphthalene;2-Bromomethylquinoline ISO 9001:2015 REACH;2-(BROMOMETHYL)QUINOLINE,PURITY:95% MIN(HPLC)
CBNumber
CB61120895
Molecular Formula
C10H8BrN
Formula Weight
222.08
MOL File
5632-15-5.mol
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2-Bromomethylquinoline Property

Melting point:
169 °C
Boiling point:
300.5±17.0 °C(Predicted)
Density 
1.518±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder
pka
3.19±0.48(Predicted)
Appearance
Off-white to pink Solid
BRN 
115410
InChIKey
NNAYPIDFVQLEDK-UHFFFAOYSA-N
CAS DataBase Reference
5632-15-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,N,Xn
Risk Statements 
22-41-51/53
Safety Statements 
26-39-61
RIDADR 
3077
WGK Germany 
3
HazardClass 
9
PackingGroup 
HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
727520
Product name
2-(Bromomethyl)quinoline
Purity
≥96.5% (GC)
Packaging
1g
Price
$155
Updated
2025/07/31
Sigma-Aldrich
Product number
727520
Product name
2-(Bromomethyl)quinoline
Purity
≥96.5% (GC)
Packaging
5g
Price
$670
Updated
2025/07/31
TCI Chemical
Product number
B6387
Product name
2-(Bromomethyl)quinoline
Purity
min. 98.0 %
Packaging
1G
Price
$129
Updated
2025/07/31
TRC
Product number
B697675
Product name
2-(Bromomethyl)quinoline
Packaging
250mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB42262
Product name
2-Bromomethylquinoline
Packaging
500mg
Price
$55
Updated
2021/12/16
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2-Bromomethylquinoline Chemical Properties,Usage,Production

Synthesis

91-63-4

5632-15-5

GENERAL METHOD: 2-methylquinoline (0.5 mmol), cuprous halide (0.75 mmol), tert-butyl hydroperoxide (TBHP, 8.0 eq., 70% aqueous solution) and acetonitrile (CH3CN, 2 mL) were added to a reaction flask and the reaction was stirred for 8 hr at 70 °C. After completion of the reaction, the mixture was diluted with water and extracted with dichloromethane (CH2Cl2, 3 x 15 mL). The halogens (X2, X = I, Br, Cl) in the organic phase were quenched with sodium thiosulfate (Na2S2O3) solution. The organic layers were combined, washed with saturated aqueous ammonium chloride (NH4Cl) solution and dried over anhydrous sodium sulfate (Na2SO4). After filtration, the solvent was removed by concentration under reduced pressure. Finally, the target product 2-bromomethylquinoline was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, v/v = 10/1).

References

[1] Advanced Synthesis and Catalysis, 2018, vol. 360, # 21, p. 4197 - 4204
[2] Tetrahedron, 2018, vol. 74, # 15, p. 1908 - 1917
[3] Tetrahedron Letters, 2014, vol. 55, # 29, p. 3892 - 3895
[4] Chemical and Pharmaceutical Bulletin, 2000, vol. 48, # 4, p. 477 - 479
[5] Journal of Organometallic Chemistry, 2017, vol. 851, p. 194 - 209

2-Bromomethylquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Bromomethylquinoline manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Bromomethylquinoline 5632-15-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Bromomethylquinoline 5632-15-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
2-Bromomethylquinoline 5632-15-5
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-09

5632-15-5, 2-BromomethylquinolineRelated Search:


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  • Quinolin-2-ylmethylbromide
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