Marbofloxacin

Brand Name(s) in US

Product Name: Marbofloxacin
CAS No.: 115550-35-1
Chemical Name: Marbofloxacin
Synonyms: Marbofloxacine;9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid;CS-939;zeniquin;Marbocyl;ZENIQUIN(R);Ma Bo effect;MARBOFLOXACIN;Marbifloxacin;Marboflaxacine
CBNumber: CB6125860
Molecular Formula: C17H19FN4O4
Formula Weight: 362.36
MOL File: 115550-35-1.mol

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Marbofloxacin Property

Melting point:: 268-269°C (dec.)
Boiling point:: 571℃
Density: 1.55±0.1 g/cm3(Predicted)
Flash point:: >110°(230°F)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform (Slightly, Heated)
form: Solid
pka: 6.02±0.20(Predicted)
color: Light Yellow
Water Solubility: Soluble in DMSO at 2mg/ml. Soluble in water or ethanol at <1mg/ml
Merck: 14,5750
InChI: InChI=1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
InChIKey: BPFYOAJNDMUVBL-UHFFFAOYSA-N
SMILES: N12C=C(C(O)=O)C(=O)C3=C1C(=C(N1CCN(C)CC1)C(F)=C3)OCN2C
CAS DataBase Reference: 115550-35-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 52/53-36/37/38
Safety Statements: 61-36-26-60
WGK Germany: 2
RTECS: UU8815140
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0000819
Product name: Marbofloxacin
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0000819
Price: $220
Updated: 2024/03/01

Sigma-Aldrich

Product number: 34039
Product name: Marbofloxacin
Purity: VETRANAL?, analytical standard
Packaging: 100MG
Price: $137
Updated: 2024/03/01

TCI Chemical

Product number: M2240
Product name: Marbofloxacin
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $158
Updated: 2024/03/01

TCI Chemical

Product number: M2240
Product name: Marbofloxacin
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $466
Updated: 2024/03/01

Alfa Aesar

Product number: J66407
Product name: Marbofloxacin, 99.7%
Packaging: 50mg
Price: $131
Updated: 2021/12/16

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Marbofloxacin Chemical Properties,Usage,Production

Brand Name(s) in US

Zeniquin, Marbocyl

Description

Marbofloxacin is a fluoroquinolone antibiotic that is active against P. multocida in vitro (MIC = 0.016 μg/ml). It exhibits broad-spectrum antibacterial activity mediated by the inhibition of DNA gyrase, with MIC values ranging from 0.016 to 0.4 and 0.19 to 1.7 μg/ml against various Gram-negative and Gram-positive bacterial isolates, respectively. In vivo, the administration of marbofloxacin (2 mg/kg, i.m.) after infection prevents the formation of pulmonary lesions in a bovine calf model of M. haemolytica A1 pneumonia. Oral marbofloxacin (2 mg/kg per day) also exhibits antileishmanial activity in a canine model of leishmaniasis, decreasing parasitic load by 72%. Formulations containing marbofloxacin have been used in the veterinary treatment of bacterial infections.

Chemical Properties

Crystalline Solid

Uses

Fluorinated quinolone antibacterial

Uses

A broad spectrum antibiotic commonly used to target Pseudomonas and Staphylococci species

Application

Marbofloxacin is an FDA-approved broad-spectrum bactericidal fluoroquinolone available in oral tablet and injectable forms. It has been shown to have varying therapeutic effects in a wide range of animal diseases in dogs, cats, horses, cattle and pigs. It can be used to treat skin and soft tissue infections in dogs and cats, urinary tract infections in dogs, some blood borne pathogens (e.g. Mycoplasma haematobium) in cats, equine infections caused by susceptible bacteria, bovine respiratory disease, and porcine respiratory disease pathogens.

Definition

ChEBI: A fluoroquinolone antibiotic that is 7-oxo-2,3-dihydro-7H-[1,3,4]oxadiazino[6,5,4-ij]quinoline substituted at positions 6, 9 and 10 by carboxy, fluoro and 4-methylpiperazin-1-yl groups, respectively. A synthetic, broad spect um bactericidal agent, it is used in veterinary medicine, although its mechanism of action is not thoroughly understood.

Side effects

The most common side effects of Marbofloxacin are vomiting, diarrhoea and loss of appetite. More serious side effects include cartilage abnormalities (which may cause difficulty walking), prolonged loss of appetite, incoordination, convulsions, depression, fever, rash, or difficulty breathing. Blindness and eye damage in cats has been a concern at high doses.

Veterinary Drugs and Treatments

Marbofloxacin is labeled for the treatment of susceptible bacterial infections in dogs and cats.

Marbofloxacin Preparation Products And Raw materials

Raw materials

Preparation Products

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Marbofloxacin Suppliers

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View Lastest Price from Marbofloxacin manufacturers

S&Y Biochem Co.,Ltd

Product: Marbifloxacin 115550-35-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 100
Release date: 2024-08-01

Hebei Chuanghai Biotechnology Co,.LTD

Product: Marbofloxacin 115550-35-1
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99 %
Supply Ability: 10000kg
Release date: 2024-08-20

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Marbofloxacin 115550-35-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0% ~ 101.0%
Supply Ability: 50KG/month
Release date: 2021-06-16

115550-35-1, MarbofloxacinRelated Search:

1-AdaMantanethylaMine 2,4,6-Collidine Gatifloxacin Methyl salicylate Azamethiphos Thiophanate-methyl Norfloxacin 1-Methylpiperazine Ofloxacin Ciprofloxacin Tribenuron methyl Levofloxacin 2-Chloro-5-chloromethylpyridine 2,6-Lutidine Methyl propyl carbonate Kresoxim-methyl METSULFURON METHYL Chromium picolinate

7h-pyrido(3,2,1-ij)(4,1,2)benzoxadiazine-6-carboxylicacid,2,3-dihydro-9-fluor

o-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

MARBOFLOXACIN

Marbofloxacin, >=99%

Marbofloxacin Solution, 1000ppm

Marbofloxacin Solution, 100ppm

CS-939

9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-PIPERAZINO)-7-OXO-7H-PYRIDO[1,2,3-IJ][1,2,4]BENZOXADIAZINE-6-CARBOXYLIC ACID

ZENIQUIN(R)

Marbofloxacin, Vetranal

7H-Pyrido3,2,1-ij4,1,2benzoxadiazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-

zeniquin

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic Acid

Marbocyl

Zeniquin(R), 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid

Marbofloxacine

9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic Acid

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylic acid

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-1H,6H-1,3,3a-triaza-phenalene-5-carboxylic acid

Marbofloxacin for peak identification CRS

Marbofloxacin Standard

Marbofloxacin&gt

Marbofloxacin CRS

Marbofloxacin Solution in Methanol, 1000μg/mL

Marboflaxacine

Marbofloxacin USP/EP/BP

MarbofloxacinQ: What is Marbofloxacin Q: What is the CAS Number of Marbofloxacin Q: What is the storage condition of Marbofloxacin Q: What are the applications of Marbofloxacin

Ma Bo effect

9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7h-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid zeniquin

9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,3,4]oxadiazino[6,5,4-ij]quinoline-6-carboxylicacid,98+%

Marbofloxacin EP/BP

Marbofloxacine|||Zeniquin|||Marbocyl

Marbifloxacin

115550-35-1

11550-35-1

C17H19FN4O4

C17H19N4O4F

API

Active Pharmaceutical Ingredients

Aromatics Compounds

Aromatics

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

115550-35-1