cannabisin F
- Product Name
- cannabisin F
- CAS No.
- 163136-19-4
- Chemical Name
- cannabisin F
- Synonyms
- cannabisin F;2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-[4-[(1E)-3-[[2-(4-hydroxyphenyl)ethyl]amino]-3-oxo-1-propen-1-yl]-2-methoxyphenoxy]-, (2Z)-
- CBNumber
- CB61315466
- Molecular Formula
- C36H36N2O8
- Formula Weight
- 624.68
- MOL File
- 163136-19-4.mol
cannabisin F Property
- Boiling point:
- 961.0±65.0 °C(Predicted)
- Density
- 1.295±0.06 g/cm3(Predicted)
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 9.78±0.31(Predicted)
N-Bromosuccinimide Price
- Product number
- CFN97809
- Product name
- CannabisinF
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $643
- Updated
- 2021/12/16
- Product number
- CD32002267
- Product name
- CannabisinF
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $998
- Updated
- 2021/12/16
cannabisin F Chemical Properties,Usage,Production
Biological Activity
Cannabisin F is a SIRT1 modulator. Cannabisin F, as a hempseed lignanamide, can be used for the research of anti-inflammatory and anti-oxidative. Cannabisin F may be a potential agent of neurodegenerative diseases as modulators of SIRT1/NF-κB and Nrf2[1]. Cannabisin F (0~15 μM; 1 hour; BV2 microglia cells) inhibits the phosphorylation of IκBα, p65, but enhances the expression of Nrf2 and HO-1[1].Cannabisin F (0~15 μM; 24 hours; BV2 microglia cells) has no significant effect on cell survival, inhibits IL-6 and TNF-α production and their mRNA expression, inhibits the production of ROS and increases the expression of SIRT1[1].
target
Immunology & Inflammation related
References
[1]. Wang S, et al. Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator. Int J Mol Sci. 2019;20(3):507. Published 2019 Jan 25.
cannabisin F Preparation Products And Raw materials
Raw materials
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