absorption
ChemicalBook > CAS DataBase List > Ferrous Bisglycinate

Ferrous Bisglycinate

absorption
Product Name
Ferrous Bisglycinate
CAS No.
20150-34-9
Chemical Name
Ferrous Bisglycinate
Synonyms
FERROUSBISGLYCINATE;FERROCHEL;Ferric Glycine;Ferrous Gglycinate;Ferrous Bis-glycine;Iron(II) bisglycinate;FERROUS(II) GLYCINATE;Ferric Glycine CoMplex;Bisglycine iron(II) salt;FERROUSBISGLYCINATECHELATE
CBNumber
CB61404339
Molecular Formula
C4H8FeN2O4
Formula Weight
203.96
MOL File
20150-34-9.mol
More
Less

Ferrous Bisglycinate Property

Melting point:
>162°C (dec.)
Boiling point:
150℃ at 101kPa
Density 
1.898 at 20℃
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly)
form 
Solid
color 
Pale Brown to Brown
Water Solubility 
Water: 35.71 mg/mL (176.83 mM)
Stability:
Hygroscopic
InChI
InChI=1S/2C2H4NO2.Fe/c2*3-1-2(4)5;/h2*3H,1H2,(H,4,5);/q2*-1;+4/p-2
InChIKey
MECJLZIFMOMXPW-UHFFFAOYSA-L
SMILES
O=C1CN[Fe+2]2(NCC(=O)[O-]2)[O-]1
LogP
-3.47 at 20℃ and pH7
Surface tension
72.87mN/m at 1g/L and 20℃
More
Less

Safety

Toxicity
LD50 orally in rats: 560 mg iron/kg (Jeppsen)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

H400Very toxic to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TRC
Product number
F307800
Product name
FerrousBisglycinate
Packaging
1g
Price
$175
Updated
2021/12/16
AK Scientific
Product number
J51778
Product name
Ferrousbisglycinate,tech.
Packaging
25g
Price
$16
Updated
2021/12/16
AK Scientific
Product number
J51778
Product name
Ferrousbisglycinate,tech.
Packaging
5g
Price
$10
Updated
2021/12/16
AK Scientific
Product number
Z1943
Product name
Ferrousbisglycinate
Packaging
1g
Price
$270
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
70240
Product name
FerrousBisglycinate
Packaging
10g
Price
$2180
Updated
2021/12/16
More
Less

Ferrous Bisglycinate Chemical Properties,Usage,Production

absorption

Iron amino acid chelates (FeAACs) are potentially helpful iron fortificants for high-phytate foods. Ferrous bisglycinate and ferric trisglycinate have one molecular equivalent of Fe2+ or Fe3+ and 2 or 3 molecular glycine equivalents, respectively. Ferrous bisglycinate and ferric trisglycinate are reportedly effective in treating iron deficiency anemia. Iron from ferrous bisglycinate is better absorbed than is that from ferrous sulfate or maize in the presence of absorption inhibitors in whole-maize meal porridge and appears not to mix with the nonheme-iron pool before its intracellular incorporation into the common intracellular iron pool. The results suggest that once iron from bis-glycinate is located intracellularly, its absorption is regulated in the same manner as iron from ferrous sulfate that labels the intracellular iron pool. Thus, ferrous bisglycinate is probably an effective and safe source of iron and is particularly useful in diets rich in phytates[1].

Uses

Nutraceutical

Uses

Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine.
Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

Uses

Ferrous Bisglycinate is used in the fortification of infant formulations and foods.

Food additive

Amino acid chelates are recommended for milk and beverage products. Ferrous bisglycinate has Generally Recognized as Safe (GRAS) status but is relatively expensive and readily promotes fat oxidation in cereal foods unless an anti-oxidant is added, and causes undesirable color reactions in some foods. Four non controlled efficacy studies with ferrous bisglycinate fortified foods have reported a marked decrease in the prevalence of anemia or iron deficiency anemia in children or adolescents. Three studies made in Brazil reported good efficacy in fortified liquid milk, sweetened bread rolls and a whey based beverage, and a fourth study in Saudi Arabia reported good efficacy in an iron fortified flavored milk drink. Recently, fer- rous bisglycinate fortified bread made from high extraction flour resulted in small but significant increases in both hemoglobin and serum ferritin when fed in a randomized controlled design to South African schoolchildren. A longer feeding period with higher iron concentrations would probably have given more impressive results. The influence of ferrous bisglycinate on stored flour was not investigated in this study. The main disadvantage of ferrous bisglycinate is its high cost. A recent cost analysis showed the cost of ferrous bisglycinate, taking bioavailability into account, to be 7–18 times that of ferrous sulfate.

Food additive

Ferrous bisglycinate is well suited to the fortification of liquid whole milk and other dairy products where the use of ferrous sulfate causes rancidity off-flavours. However, ferrous bisglycinate can also cause rancidity by oxidizing fats in food, which can be a problem in cereal flours and weaning cereals unless an antioxidant is added as well. Furthermore, the bisglycinate is much more expensive than many other iron compounds.

Side effects

Ferrous Bisglycinate is a novel amino acid iron chelate that is more bioavailable and has fewer gastrointestinal (GI) adverse effects than iron salts. Adverse effects such as constipation, diarrhoea, stomach cramps or upset stomach may occur with Ferrous Bisglycinate. However, usually these effects are temporary and can recover on their own. Iron may cause your faeces to become darker; this effect is harmless. In addition, in the event of a severe allergic reaction to the drug, you need to stop taking it immediately and contact your doctor.

Synthesis

600kg water is added in 1500L reactor, 150kg glycine, 1.5kg carbonyl iron dust, and heating is added under agitation. Stir for 20 minutes to 65 DEG C, then add 550kg ferrous sulfate heptahydrates, 37.5kg maltodextrins, 0.3kg silica, 78 DEG C reaction 30 minutes, reaction complete. Reaction solution sieves heat filtering with 100 mesh stainless sheets of steel, and the filtrate is dried with a pressure spray drying tower, obtained To yellowish-brown green powder Ferrous Bisglycinate 490kg.

References

[1] Adelia C Bovell-Benjamin, Lindsay H Allen, Fernando E Viteri. “Iron absorption from ferrous bisglycinate and ferric trisglycinate in whole maize is regulated by iron status123.” American Journal of Clinical Nutrition 71 6 (2000): Pages 1503-1509.

Ferrous Bisglycinate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ferrous Bisglycinate Suppliers

HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
HBCChem, Inc.
Tel
--
Fax
--
Email
Sales@hbcchem-inc.com
Country
United States
ProdList
887
Advantage
50
More
Less

View Lastest Price from Ferrous Bisglycinate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Ferrous Bisglycinate 20150-34-9
Price
US $120.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-27
Shijiazhuang Donghua Jinlong Chemical Co., LTD
Product
Ferrous Glycinate 20150-34-9
Price
US $0.00/kg
Min. Order
10kg
Purity
98%
Supply Ability
20000MT
Release date
2024-05-22
Shijiazhuang Donghua Jinlong Chemical Co., LTD
Product
Ferrous Glycinate 20150-34-9
Price
US $0.00/kg
Min. Order
10kg
Purity
98.5%
Supply Ability
2000mt
Release date
2024-06-25

20150-34-9, Ferrous BisglycinateRelated Search:


  • FERROUSBISGLYCINATE
  • FERROUSBISGLYCINATECHELATE
  • Ferric Glycine
  • FERROCHEL
  • Ferrous Bisglycinate Food Grade
  • Ferric Glycine CoMplex
  • Iron, bis(glycinato-kN,kO)-
  • Bisglycine iron(II) salt
  • Iron(II) bisglycinate
  • Iron, bis(glycinato-κN,κO)-
  • Ferrous Bisglycinate USP/EP/BP
  • Ferrous Gglycinate
  • Ferrous Bis-glycine
  • FERROUS(II) GLYCINATE
  • 20150-34-9
  • 120150-34-9
  • 2015-34-9