Naringin dihydrochalcone
- Product Name
- Naringin dihydrochalcone
- CAS No.
- 18916-17-1
- Chemical Name
- Naringin dihydrochalcone
- Synonyms
- Naringin DC;Naringine DC;Senior saccharin;Naringin dihydrochal;NARINGINDIHYDROHALCONE;NAGINGINDIHYDROCHALCONE;NARINGIN DIHYDROCHALCONE;NARINGIN DIHYDOROCHALCONE;Naringin dihydrochalcone-RM;ranosyl)- β-D-glucopyranosyl]oxy]-
- CBNumber
- CB6140982
- Molecular Formula
- C27H34O14
- Formula Weight
- 582.56
- MOL File
- 18916-17-1.mol
Naringin dihydrochalcone Property
- Melting point:
- 131-132°C
- Boiling point:
- 916.8±65.0 °C(Predicted)
- Density
- 1.63±0.1 g/cm3(Predicted)
- vapor pressure
- 0Pa at 20-50℃
- FEMA
- 4495 | NARINGIN DIHYDROCHALCONE
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Soluble in DMSO
- pka
- 6.85±0.40(Predicted)
- form
- Powder
- color
- White to Off-white
- JECFA Number
- 2208
- InChIKey
- CWBZAESOUBENAP-CUDWAMJSNA-N
- LogP
- -0.703-1.01 at 22.6℃ and pH5-9
- CAS DataBase Reference
- 18916-17-1(CAS DataBase Reference)
Safety
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- CDS003175
- Product name
- naringin dihydrochalcone
- Purity
- AldrichCPR
- Packaging
- 1G
- Price
- $87.5
- Updated
- 2025/07/31
- Product number
- 27791
- Product name
- Naringin Dihydrochalcone
- Packaging
- 5g
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 27791
- Product name
- Naringin Dihydrochalcone
- Packaging
- 50g
- Price
- $503
- Updated
- 2024/03/01
- Product number
- 27791
- Product name
- Naringin Dihydrochalcone
- Packaging
- 10g
- Price
- $152
- Updated
- 2024/03/01
- Product number
- 27791
- Product name
- Naringin Dihydrochalcone
- Packaging
- 25g
- Price
- $336
- Updated
- 2024/03/01
Naringin dihydrochalcone Chemical Properties,Usage,Production
Description
Naringin dihydrochalcone is an artificial sweetener and flavonoid that has been isolated from various plants and has antioxidant activity. It scavenges ABTS (Item No. 27317), oxygen, and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell free assays (IC50s = 24, 322.8, and 318.9 μM, respectively).
Uses
Naringin Dihydrochalcone is an intense sweetener and strong antioxidant compound which displays anti-allegeric activity.
Definition
ChEBI: Naringin dihydrochalcone is a member of flavonoids and a glycoside.
Synthesis
10236-47-2
18916-17-1
Naringin was used as a raw material to synthesize 1-(4-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,6-dihydroxyphenyl)-3-( 4-hydroxyphenyl)propan-1-one was prepared in the following general procedure: 120 g of the natural extract (containing 600 g of 8% naringin) was dissolved in potassium hydroxide solution and filtered to obtain a clarified solution. The filtrate was transferred to a 2000 ml autoclave and 200 g of ethanol and 3 g of palladium carbon catalyst were added. Hydrogen was introduced at 55°C, maintaining the pressure at 1~2MPa, and the reaction was carried out for 5~7 hours until the hydrogen absorption was basically completed. The reaction solution was removed and filtered to remove the palladium-carbon catalyst. Subsequently, the hydrogenated solution was acidified with hydrochloric acid, the pH was adjusted to 5-7, and stirred thoroughly to induce crystallization, and a white solid was rapidly precipitated. The mixture was cooled to 20 °C and filtered, and the resulting wet product was dried under reduced pressure at 60 °C to give 118 g of dihydronaringenin chalcone as a white powder with 98.9% liquid phase purity and 98% molar yield. The product needs to be stored in a cool place under light nitrogen protection.
target
NF-κB
References
[1] Patent: CN105801636, 2016, A. Location in patent: Paragraph 0022
[2] Journal of Agricultural and Food Chemistry, 2003, vol. 51, # 11, p. 3309 - 3312
Naringin dihydrochalcone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Naringin dihydrochalcone manufacturers
- Product
- Naringin Dihydorchalcone 18916-17-1
- Price
- US $1200.00-1100.00/ton
- Min. Order
- 1ton
- Purity
- 99%
- Supply Ability
- 1000T/M
- Release date
- 2025-10-22
- Product
- Naringin dihydrochalcone 18916-17-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 1000kg
- Release date
- 2025-04-27
- Product
- Naringin dihydrochalcone 18916-17-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-08