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trans-Chalcone

Product Name
trans-Chalcone
CAS No.
614-47-1
Chemical Name
trans-Chalcone
Synonyms
(E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
CBNumber
CB7746253
Molecular Formula
C15H12O
Formula Weight
208.26
MOL File
614-47-1.mol
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trans-Chalcone Property

Melting point:
55-59 °C
Boiling point:
208 °C25 mm Hg(lit.)
Density 
1.0712
refractive index 
1.5361 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
color 
Pale Yellow
Odor
at 100.00 %. floral balsam herbal
Odor Type
floral
Water Solubility 
Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water.
Merck 
14,2037
BRN 
509985
LogP
4.013 (est)
CAS DataBase Reference
614-47-1(CAS DataBase Reference)
NIST Chemistry Reference
Benzalacetophenone(614-47-1)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37
Safety Statements 
22-36/37/39-45
WGK Germany 
3
RTECS 
UD5576750
HS Code 
29143990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
136123
Product name
trans-Chalcone
Purity
97%
Packaging
5g
Price
$42.7
Updated
2024/03/01
Sigma-Aldrich
Product number
136123
Product name
trans-Chalcone
Purity
97%
Packaging
100g
Price
$62.4
Updated
2024/03/01
Alfa Aesar
Product number
A14734
Product name
trans-Chalcone, 97%
Packaging
100g
Price
$53
Updated
2024/03/01
Alfa Aesar
Product number
A14734
Product name
trans-Chalcone, 97%
Packaging
500g
Price
$175
Updated
2024/03/01
TRC
Product number
C291860
Product name
trans-Chalcone
Packaging
5g
Price
$65
Updated
2021/12/16
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trans-Chalcone Chemical Properties,Usage,Production

Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Chemical Properties

Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.

Uses

trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.

Definition

ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.

Application

trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).

Preparation

trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058

General Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Biological Activity

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Biochem/physiol Actions

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Synthesis

Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.

trans-Chalcone Preparation Products And Raw materials

Raw materials

Preparation Products

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trans-Chalcone Suppliers

Anhui Tianjia Chemical Science & Technology Co.,Ltd.
Tel
0550-2392698 18355069969
Fax
0550-2392698
Email
tianjiachem@hotmail.com
Country
China
ProdList
17
Advantage
57
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
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View Lastest Price from trans-Chalcone manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
trans-Chalcone 614-47-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-06-18
Career Henan Chemical Co
Product
trans-Chalcone 614-47-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000kgs
Release date
2020-01-02

614-47-1, trans-ChalconeRelated Search:


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