trans-Chalcone
- Product Name
- trans-Chalcone
- CAS No.
- 614-47-1
- Chemical Name
- trans-Chalcone
- Synonyms
- (E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
- CBNumber
- CB7746253
- Molecular Formula
- C15H12O
- Formula Weight
- 208.26
- MOL File
- 614-47-1.mol
trans-Chalcone Property
- Melting point:
- 55-59 °C
- Boiling point:
- 208 °C25 mm Hg(lit.)
- Density
- 1.0712
- refractive index
- 1.5361 (estimate)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly)
- form
- Solid
- color
- Pale Yellow
- Odor
- at 100.00 %. floral balsam herbal
- Odor Type
- floral
- Water Solubility
- Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water.
- Merck
- 14,2037
- BRN
- 509985
- LogP
- 4.013 (est)
- CAS DataBase Reference
- 614-47-1(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzalacetophenone(614-47-1)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37
- Safety Statements
- 22-36/37/39-45
- WGK Germany
- 3
- RTECS
- UD5576750
- HS Code
- 29143990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 136123
- Product name
- trans-Chalcone
- Purity
- 97%
- Packaging
- 5g
- Price
- $42.7
- Updated
- 2024/03/01
- Product number
- 136123
- Product name
- trans-Chalcone
- Purity
- 97%
- Packaging
- 100g
- Price
- $62.4
- Updated
- 2024/03/01
- Product number
- A14734
- Product name
- trans-Chalcone, 97%
- Packaging
- 100g
- Price
- $53
- Updated
- 2024/03/01
- Product number
- A14734
- Product name
- trans-Chalcone, 97%
- Packaging
- 500g
- Price
- $175
- Updated
- 2024/03/01
- Product number
- C291860
- Product name
- trans-Chalcone
- Packaging
- 5g
- Price
- $65
- Updated
- 2021/12/16
trans-Chalcone Chemical Properties,Usage,Production
Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Chemical Properties
Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.
Uses
trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.
Definition
ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.
Application
trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).
Preparation
trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones
Synthesis Reference(s)
Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058
General Description
trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.
Biological Activity
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Biochem/physiol Actions
trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.
Synthesis
Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.
trans-Chalcone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from trans-Chalcone manufacturers
- Product
- trans-Chalcone 614-47-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 50000kg
- Release date
- 2024-06-18
- Product
- trans-Chalcone 614-47-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kgs
- Release date
- 2020-01-02