trans-Chalcone

Product Name: trans-Chalcone
CAS No.: 614-47-1
Chemical Name: trans-Chalcone
Synonyms: (E)-CHALCONE;BENZALACETOPHENONE;cone;BENZYLIDENEACETOPHENONE;1,3-DIPHENYL-2-PROPEN-1-ONE;CHALKONE;1,3-DIPHENYL-2-PROPENONE;2-Propen-1-one, 1,3-diphenyl-, (E)-;Nsc167107;trans-ChaL
CBNumber: CB7746253
Molecular Formula: C15H12O
Formula Weight: 208.26
MOL File: 614-47-1.mol

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trans-Chalcone Property

Melting point:: 55-59 °C
Boiling point:: 208 °C25 mm Hg(lit.)
Density: 1.0712
refractive index: 1.5361 (estimate)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly)
form: Solid
color: Pale Yellow
Odor: at 100.00 %. floral balsam herbal
Odor Type: floral
Water Solubility: Soluble in chloroform, ether, benzene, and ethanol (slightly). Insoluble in water.
Merck: 14,2037
BRN: 509985
InChI: 1S/C15H12O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11+
InChIKey: DQFBYFPFKXHELB-VAWYXSNFSA-N
SMILES: [H]\C(=C(\[H])C(=O)c1ccccc1)c2ccccc2
LogP: 4.013 (est)
CAS DataBase Reference: 614-47-1(CAS DataBase Reference)
NIST Chemistry Reference: Benzalacetophenone(614-47-1)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37
Safety Statements: 22-36/37/39-45
WGK Germany: 3
RTECS: UD5576750
HS Code: 29143990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 136123
Product name: trans-Chalcone
Purity: 97%
Packaging: 5g
Price: $44
Updated: 2025/07/31

Sigma-Aldrich

Product number: 136123
Product name: trans-Chalcone
Purity: 97%
Packaging: 100g
Price: $64.3
Updated: 2025/07/31

TRC

Product number: C291860
Product name: trans-Chalcone
Packaging: 5g
Price: $65
Updated: 2021/12/16

AK Scientific

Product number: 9216AB
Product name: trans-Chalcone
Packaging: 25g
Price: $27
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC34413
Product name: trans-Chalcone
Packaging: 100g
Price: $40
Updated: 2021/12/16

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trans-Chalcone Chemical Properties,Usage,Production

Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Chemical Properties

Trans-Chalcone is a yellowish crystals. M.P. 58℃. (trans-isomer). M .P. 46℃. (cis-isomer).Sp.Gr. 1.07 (liquid).Insoluble in water, soluble in alcohol (poorly) and oils.

Uses

trans-Chalcone is a positive allosteric modulator of α7 nicotinic acetylcholine receptors and exhibits antioxidant activity.

Definition

ChEBI: Chalcone is a member of the class of chalcones that is acetophenone in which one of the methyl hydrogens has been replaced by a benzylidene group. It has a role as a plant metabolite. It is a member of styrenes and a member of chalcones.

Application

trans-Chalcone was used in the synthesis of cis and trans diphenyl cyclopropane. It was also used in screening of surface adsorbed species of isobutybenzene and 4-isobutylacetophenone on bulk fosfotungstic Wells-Dawson acid (H6P2W18O62.xH2O).

Preparation

trans-Chalcones have been obtained in good yields and selectivities following an environmentally friendly methodology by using montmorillonite KSF as a reusable heterogeneous catalyst.
Clay-catalysed solventless synthesis of trans-chalcones

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 4724, 1982 DOI: 10.1021/ja00381a058

General Description

trans-Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer.

Biological Activity

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Biochem/physiol Actions

trans-Chalcone exhibits antifungal activity against Trichophyton rubrum. It is inhibitor of fatty acid synthase and α-amylase. It induces programmed cell death due to reduced mitochondrial transmembrane potential in Arabidopsis thaliana roots.

Synthesis

Trans-Chalcone is synthesized by condensation of Benzaldehyde with Acetophenone.

trans-Chalcone Preparation Products And Raw materials

Raw materials

Preparation Products

α-Naphthoflavone Chalcone 3,5-DIPHENYLPYRAZOLE

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trans-Chalcone Suppliers

Belgium 1 Canada 1 China 186 Czech 1 Europe 1 France 1 Germany 5 India 18 Japan 2 South Korea 1 Switzerland 1 The Netherlands 3 Ukraine 1 United Kingdom 10 United States 42 Global 274

Anhui Tianjia Chemical Science & Technology Co.,Ltd.

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Alfa Aesar

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Accela ChemBio Co.,Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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View Lastest Price from trans-Chalcone manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: trans-Chalcone 614-47-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-03-01

Career Henan Chemical Co

Product: trans-Chalcone 614-47-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000kgs
Release date: 2020-01-02

614-47-1, trans-ChalconeRelated Search:

PROPYLENE tert-Butylchlorodiphenylsilane trans,trans-2,4-Undecadienal 1,3-Diphenyl-2-thiourea DIPHENYLCYCLOPROPENONE Dichlorodiphenylsilane Diphenylphosphine Biphenyl Diphenylsilane Diphenylmethane Chlorodiphenylphosphine Neosperidin dihydrochalcone 3-HYDROXYFLAVONE Galangin 7,8-Dihydroxyflavone α-Naphthoflavone 4'-METHOXYCHALCONE Apigenin

PHENYL STYRYL KETONE

(2E)-1,3-DIPHENYLPROP-2-EN-1-ONE

2-BENZALACETOPHENONE

2-BENZYLIDENEACETOPHENONE

3-PHENYLACRYLOPHENONE

TRANS-BENZYLIDENEACETOPHENONE

TRANS-CHALCONE

1,3-DIPHENYL-2-PROPEN-1-ONE

1,3-DIPHENYL-2-PROPEN-I-ONE

1,3-DIPHENYL-2-PROPENONE

1,3-DIPHENYL-3-PROPEN-1-ONE

1,3-DIPHENYLPROP-2-EN-1-ONE

phenyltrans-styrylketone

trans-benzalacetophenone

(e)-1,3-diphenyl-2-propen-1-one

(e)-benzylideneacetophenone

2-Propen-1-one, 1,3-diphenyl-, (E)-

3-diphenyl-(e)-2-propen-1-on

phenyl(e)-2-phenylethenylketone

cone

trans-ChaL

Chalcone(BenzalAcetophenone)

CHALKONE

(E)-CHALCONE

BENZYLIDENEACETOPHENONE

BENZYLIDINEACETOPHENONE

BENZALACETOPHENONE

(E)-1,3-Diphenylpropen-3-one

(E)-1-Benzoyl-2-phenylethylene

trans-1,3-Diphenyl-2-propen-1-one

(αE)-β-Phenylacrylophenone

(βE)-β-Phenylacrylophenone

Phenyl[(E)-styryl] ketone

trans-Benzalacetophenone, (E)-1,3-Diphenylprop-2-en-1-one

Nsc167107

trans-Chalcone 97%

<i>trans</i>-Chalcone

2-Propen-1-one, 1,3-diphenyl-, (2E)-

rans-chalcone

Benzylidence aceptophenone (Chalcone-97%)

trans-Chalcone 614-47-1

Chalcone|||Cinnamophenone|||Chalkone

trans-Chalcone, 10 mM in DMSO

614-47-1

C6H5COCHCHC6H5

Organic Building Blocks

Ketones

Building Blocks

Carbonyl Compounds

C15 to C38

Flavonoids