Naringin dihydrochalcone

Product Name: Naringin dihydrochalcone
CAS No.: 18916-17-1
Chemical Name: Naringin dihydrochalcone
Synonyms: Naringin DC;Naringine DC;Senior saccharin;Naringin dihydrochal;NARINGINDIHYDROHALCONE;NAGINGINDIHYDROCHALCONE;NARINGIN DIHYDROCHALCONE;NARINGIN DIHYDOROCHALCONE;Naringin dihydrochalcone-RM;ranosyl)- β-D-glucopyranosyl]oxy]-
CBNumber: CB6140982
Molecular Formula: C27H34O14
Formula Weight: 582.56
MOL File: 18916-17-1.mol

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Naringin dihydrochalcone Property

Melting point:: 131-132°C
Boiling point:: 916.8±65.0 °C(Predicted)
Density: 1.63±0.1 g/cm3(Predicted)
vapor pressure: 0Pa at 20-50℃
FEMA: 4495 | NARINGIN DIHYDROCHALCONE
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Soluble in DMSO
pka: 6.85±0.40(Predicted)
form: Powder
color: White to Off-white
JECFA Number: 2208
InChIKey: CWBZAESOUBENAP-CUDWAMJSNA-N
LogP: -0.703-1.01 at 22.6℃ and pH5-9
CAS DataBase Reference: 18916-17-1(CAS DataBase Reference)

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Safety

HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS003175
Product name: naringin dihydrochalcone
Purity: AldrichCPR
Packaging: 1G
Price: $87.5
Updated: 2025/07/31

Cayman Chemical

Product number: 27791
Product name: Naringin Dihydrochalcone
Packaging: 5g
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 27791
Product name: Naringin Dihydrochalcone
Packaging: 50g
Price: $503
Updated: 2024/03/01

Cayman Chemical

Product number: 27791
Product name: Naringin Dihydrochalcone
Packaging: 10g
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 27791
Product name: Naringin Dihydrochalcone
Packaging: 25g
Price: $336
Updated: 2024/03/01

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Naringin dihydrochalcone Chemical Properties,Usage,Production

Description

Naringin dihydrochalcone is an artificial sweetener and flavonoid that has been isolated from various plants and has antioxidant activity. It scavenges ABTS (Item No. 27317), oxygen, and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell free assays (IC50s = 24, 322.8, and 318.9 μM, respectively).

Uses

Naringin Dihydrochalcone is an intense sweetener and strong antioxidant compound which displays anti-allegeric activity.

Definition

ChEBI: Naringin dihydrochalcone is a member of flavonoids and a glycoside.

Synthesis

10236-47-2

18916-17-1

Naringin was used as a raw material to synthesize 1-(4-((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,6-dihydroxyphenyl)-3-( 4-hydroxyphenyl)propan-1-one was prepared in the following general procedure: 120 g of the natural extract (containing 600 g of 8% naringin) was dissolved in potassium hydroxide solution and filtered to obtain a clarified solution. The filtrate was transferred to a 2000 ml autoclave and 200 g of ethanol and 3 g of palladium carbon catalyst were added. Hydrogen was introduced at 55°C, maintaining the pressure at 1~2MPa, and the reaction was carried out for 5~7 hours until the hydrogen absorption was basically completed. The reaction solution was removed and filtered to remove the palladium-carbon catalyst. Subsequently, the hydrogenated solution was acidified with hydrochloric acid, the pH was adjusted to 5-7, and stirred thoroughly to induce crystallization, and a white solid was rapidly precipitated. The mixture was cooled to 20 °C and filtered, and the resulting wet product was dried under reduced pressure at 60 °C to give 118 g of dihydronaringenin chalcone as a white powder with 98.9% liquid phase purity and 98% molar yield. The product needs to be stored in a cool place under light nitrogen protection.

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References

[1] Patent: CN105801636, 2016, A. Location in patent: Paragraph 0022
[2] Journal of Agricultural and Food Chemistry, 2003, vol. 51, # 11, p. 3309 - 3312

Naringin dihydrochalcone Preparation Products And Raw materials

Raw materials

Preparation Products

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Naringin dihydrochalcone Suppliers

China 317 China Hong Kong 1 Germany 1 India 5 United Kingdom 7 United States 34 USA 1 Global 366

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View Lastest Price from Naringin dihydrochalcone manufacturers

Lianyungang Kaiyu Environmental Tech Co., Ltd.

Product: Naringin Dihydorchalcone 18916-17-1
Price: US $1200.00-1100.00/ton
Min. Order: 1ton
Purity: 99%
Supply Ability: 1000T/M
Release date: 2025-10-22

Shaanxi Xianhe Biotech Co., Ltd

Product: Naringin dihydrochalcone 18916-17-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 1000kg
Release date: 2025-04-27

Hebei Chuanghai Biotechnology Co., Ltd

Product: Naringin dihydrochalcone 18916-17-1
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-08

18916-17-1, Naringin dihydrochalconeRelated Search:

Neosperidin dihydrochalcone Naringin trans-Chalcone Naringenin Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) NARINGENIN CHALCONE Kaempferol Hesperetin Phloretin Sclareol Apigenin Phlorizin Prunin Saccharin PONCIRIN NARINGIN HYDRATE NEOERIOCITRIN Naringin dihydrochalcone

1-[4-[[2-o-(6-deoxy-l-mannopyranosyl)-d-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

NARINGIN DIHYDROCHALCONE

NAGINGINDIHYDROCHALCONE

Naringin DC

NARINGINDIHYDROHALCONE

NARINGIN DIHYDOROCHALCONE

1-Propanone,1-[4-[[2-O-(6-deoxy-α-L-mannopy

2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-

ranosyl)- β-D-glucopyranosyl]oxy]-

Senior saccharin

Naringin dihydrochalcone 18916-17-1

1-[4-[[4,5-dihydroxy-6-(hydroxymethyl)-3-[(3,4,5-trihydroxy-6-methyl-2-oxanyl)oxy]-2-oxanyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone

Naringin dihydrochal

Naringin Dihydrochalcone(Naringin DC)

1-Propanone, 1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-

Naringin dihydrochalcone USP/EP/BP

99% purity Naringin dihydrochalcone

1-[4-[(3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)propan-1-one

1-(4-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,6-dihydroxyphenyl)-3-(4-hydroxyphenyl)propan-1-one

1-[4-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)propan-1-one (naringin-dihydrochalcone)

Naringine DC

Naringin dihydrochalcone-RM

3,5-dihydroxy-4-[3-(4-hydroxyphenyl)propanoyl]phenyl 2-O-(6-deoxy-α-Dmannopyranosyl)-β-D-gulopyranoside

Naringin dihydrochalcone, 10 mM in DMSO

Neohesperidin dihydrochalcone EP Impurity D (Naringin dihydrochalcone)

Abmole M3920-100mg Naringin dihydrochalcone 18916-17-1

18916-17-1

18915-17-1

C27H34O14

C27H32O142HCl

Inhibitors

reagent

standard substance

CITRIMORE

Flavanones

Natural Plant Extract