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3-BROMO-5-NITROBENZALDEHYDE

Product Name
3-BROMO-5-NITROBENZALDEHYDE
CAS No.
355134-13-3
Chemical Name
3-BROMO-5-NITROBENZALDEHYDE
Synonyms
3-BROMO-5-NITROBENZALDEHYDE;3-Nitro-5-bromo-benzaldehyde;3-Bromo-5-formylnitrobenzene;3-Fluoro-5-nitrobenzaldehyde;Benzaldehyde,3-bromo-5-nitro-;3-Bromo-5-nitrobenzaldehyde 95%;3-BroMo-5-nitrobenzaldehyde, 97+%
CBNumber
CB61471016
Molecular Formula
C7H4BrNO3
Formula Weight
230.02
MOL File
355134-13-3.mol
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3-BROMO-5-NITROBENZALDEHYDE Property

Melting point:
101-106 °C
Boiling point:
306.9±27.0 °C(Predicted)
Density 
1.781
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
soluble in Methanol
form 
Powder
color 
Pale brown
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-43
Safety Statements 
26-36/37
WGK Germany 
3
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
702986
Product name
3-Bromo-5-nitrobenzaldehyde
Purity
97%
Packaging
250mg
Price
$69.5
Updated
2023/01/07
Sigma-Aldrich
Product number
702986
Product name
3-Bromo-5-nitrobenzaldehyde
Purity
97%
Packaging
1g
Price
$125
Updated
2023/01/07
TCI Chemical
Product number
B4982
Product name
3-Bromo-5-nitrobenzaldehyde
Packaging
1G
Price
$73
Updated
2025/07/31
TCI Chemical
Product number
B4982
Product name
3-Bromo-5-nitrobenzaldehyde
Packaging
5G
Price
$219
Updated
2025/07/31
TRC
Product number
B699445
Product name
3-Bromo-5-nitrobenzaldehyde
Packaging
100mg
Price
$60
Updated
2021/12/16
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3-BROMO-5-NITROBENZALDEHYDE Chemical Properties,Usage,Production

Uses

3-Fluoro-5-nitrobenzaldehyde is used as a reactant in the design and synthesis of selective activators of cardiac myosin.

Synthesis Reference(s)

The Journal of Organic Chemistry, 72, p. 5867, 2007 DOI: 10.1021/jo070477u

Synthesis

99-61-6

355134-13-3

General procedure for the synthesis of 3-bromo-5-nitrobenzaldehyde from m-nitrobenzaldehyde: 3-nitrobenzaldehyde (1.0 g, 6.6 mmol) was dissolved in concentrated sulfuric acid (4.0 mL) at room temperature, followed by batchwise addition of N-bromosuccinimide (1.4 g, 7.9 mmol). The reaction mixture was heated to 65 °C and maintained at this temperature for 1 hour. After completion of the reaction, it was cooled to room temperature and the reaction solution was slowly poured into ice water, the solid was precipitated and collected by filtration. The crude product was dried with anhydrous sodium sulfate and purified by recrystallization through a solvent mixture of ethyl acetate/petroleum ether (1:10, v/v) to finally obtain 3-bromo-5-nitrobenzaldehyde (1.3 g, 82% yield) as white crystals. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 10.09 (s, 1H), 8.79-8.55 (m, 2H), 8.51 (s, 1H).

References

[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 12, p. 5235 - 5244
[2] Journal of Organic Chemistry, 2007, vol. 72, # 15, p. 5867 - 5869
[3] European Journal of Medicinal Chemistry, 2016, vol. 116, p. 46 - 58
[4] Journal of the American Chemical Society, 2007, vol. 129, # 15, p. 4512 - 4513
[5] Patent: WO2009/153313, 2009, A1. Location in patent: Page/Page column 185

3-BROMO-5-NITROBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-5-NITROBENZALDEHYDE Suppliers

Americas 1 China 110 Europe 1 Germany 1 India 8 Japan 1 Switzerland 1 United Kingdom 2 United States 13 Global 138
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 3-BROMO-5-NITROBENZALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-Bromo-5-nitrobenzaldehyde 355134-13-3
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-07-08
Henan Aochuang Chemical Co.,Ltd.
Product
3-BROMO-5-NITROBENZALDEHYDE 355134-13-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Career Henan Chemical Co
Product
3-BROMO-5-NITROBENZALDEHYDE 355134-13-3
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

355134-13-3, 3-BROMO-5-NITROBENZALDEHYDERelated Search:

5'-BROMO-2'-HYDROXY-3'-NITROACETOPHENONE 3-Bromo-5-nitrobenzoic acid 3-BROMO-5-NITROBENZALDEHYDE 5-BroMo-3-nitrosalicylaldehyde 3-BROMO-5-NITROBENZAMIDE 3-BROMO-2-HYDROXY-5-NITROBENZALDEHYDE 3-BROMO-4-NITROBENZALDEHYDE 4-BROMO-2-NITROBENZALDEHYDE 4-BROMO-3-NITRO-BENZALDEHYDE 2-NITRO 5-BROMO-BENZALDEHYDE 3-BROMO-4-METHYL-5-NITROBENZOIC ACID RARECHEM AL BE 0950 CHEMBRDG-BB 6625984 5'-BROMO-2'-HYDROXY-3'-NITROPROPIOPHENONE 1-BROMO-2-NITROBENZALDEHYDE-D4 3-bromo-2-nitrobenzaldehyde 2-Bromo-6-nitrobenzaldehyde 1-BROMO-4-NITROBENZALDEHYDE-D4

  • 3-BROMO-5-NITROBENZALDEHYDE
  • 3-Bromo-5-nitrobenzaldehyde 95%
  • 3-Fluoro-5-nitrobenzaldehyde
  • Benzaldehyde,3-bromo-5-nitro-
  • 3-BroMo-5-nitrobenzaldehyde, 97+%
  • 3-Bromo-5-formylnitrobenzene
  • 3-Nitro-5-bromo-benzaldehyde
  • 355134-13-3
  • 355134-13-1
  • Nitro CompoundsChemical Synthesis
  • Aldehydes
  • C7Organic Building Blocks
  • Carbonyl Compounds
  • New Products for Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks