ChemicalBook > CAS DataBase List > 4-HYDROXY-6-METHOXYQUINOLINE

4-HYDROXY-6-METHOXYQUINOLINE

Product Name: 4-HYDROXY-6-METHOXYQUINOLINE
CAS No.: 23432-39-5
Chemical Name: 4-HYDROXY-6-METHOXYQUINOLINE
Synonyms: 6-METHOXYQUINOLIN-4-OL;Nsc76096;6-METHOXY-4-QUINOLINOL;6-Methoxyl-4-quinolinol;6-Methoxyquinoline-4-ol;4-Quinolinol, 6-methoxy-;6-METHOXY-4(1H)-QUINOLINONE;6-METHOXYQUINOLIN-4(1H)-ONE;4-HYDROXY-6-METHOXYQUINOLINE;6-METHOXY-4-HYDROXYQUINOLINE
CBNumber: CB6149778
Molecular Formula: C10H9NO2
Formula Weight: 175.18
MOL File: 23432-39-5.mol

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4-HYDROXY-6-METHOXYQUINOLINE Property

Melting point:: 225-244 °C(Solv: water (7732-18-5))
Boiling point:: 351.8±22.0 °C(Predicted)
Density: 1.258±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
pka: 4.40±0.40(Predicted)
Appearance: Off-white to gray Solid

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-39
WGK Germany: 3
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BBO000055
Product name: 4-Hydroxy-6-methoxyquinoline
Purity: Aldrich
Packaging: 1g
Price: $259
Updated: 2025/07/31

TRC

Product number: M323608
Product name: 6-Methoxyquinolin-4-ol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W017452
Product name: 6-Methoxyquinolin-4-ol
Purity: 97.24%
Packaging: 1g
Price: $13
Updated: 2021/12/16

ChemScene

Product number: CS-W017452
Product name: 6-Methoxyquinolin-4-ol
Purity: 97.24%
Packaging: 5g
Price: $57
Updated: 2021/12/16

AK Scientific

Product number: J97228
Product name: 6-Methoxy-4-hydroxyquinoline
Packaging: 5g
Price: $80
Updated: 2021/12/16

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4-HYDROXY-6-METHOXYQUINOLINE Chemical Properties,Usage,Production

Synthesis

28027-16-9

23432-39-5

General procedure for the synthesis of 4-hydroxy-6-methoxyquinoline-3-carboxylic acid from 4-hydroxy-6-methoxyquinoline-3-carboxylic acid: 4-hydroxy-6-methoxyquinoline-3-carboxylic acid (7, 15.7 g, 72 mmol) was dissolved in 80 mL of diphenyl ether and heated to 245 °C in a metal bath for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and dissolved in 200 mL of hexane. The mixture was stirred for 3 hours and then filtered. The resulting solid was washed with ethyl acetate and dried to give 6-methoxyquinolin-4-ol (8, 12.5 g, 72 mmol, 100% yield). The product was characterized by 1H-NMR (DMSO-d6): δ= 3.81 (s, 3H), 5.99 (d, 1H), 7.28 (dd, 1H), 7.48-7.53 (m, 2H), 7.86 (d, 1H), 11.87 (bs, 1H).Results of the LC-MS analysis: retention time (Rt) = 0.87 min; mass spectrum (MS): m/z = 176 [M + H]+.

References

[1] Tetrahedron Letters, 2017, vol. 58, # 8, p. 794 - 796
[2] Journal of the American Chemical Society, 1946, vol. 68, p. 1204,1206
[3] Organic Syntheses, 1955, vol. Coll. Vol. III, p. 272
[4] Journal of the American Chemical Society, 1947, vol. 69, p. 1659,1660
[5] Chemical and Pharmaceutical Bulletin, 2007, vol. 55, # 5, p. 821 - 824

4-HYDROXY-6-METHOXYQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-HYDROXY-6-METHOXYQUINOLINE manufacturers

Career Henan Chemical Co

Product: 4-HYDROXY-6-METHOXYQUINOLINE 23432-39-5
Price: US $10.00/KG/Tin
Min. Order: 1KG
Purity: 99%
Supply Ability: 100
Release date: 2019-06-28

23432-39-5, 4-HYDROXY-6-METHOXYQUINOLINERelated Search:

4-HYDROXY-6-METHOXYQUINOLINE 4-HYDROXY-8-METHOXYQUINOLINE ETHYL 4-HYDROXY-6-METHOXYQUINOLINE-3-CARBOXYLATE Methyl 4-hydroxy-8-methoxyquinoline-2-carboxylate 7-Methoxy-4-quinolinol 4-Hydroxy-7-methoxyquinoline,4-HYDROXY-7-METHOXYQUINOLINE 4-HYDROXY-7-METHOXYQUINOLINE-3-CARBOXYLIC ACID 4-Hydroxy-5-methoxyquinoline- 3-carboxylic acid ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLATE (S)-1-Boc-3-methylpiperazine 4-HYDROXY-7-METHOXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 4-HYDROXY-6-METHOXYQUINOLINE-3-CARBOXYLIC ACID,3-CARBOXY-4-HYDROXY-6-METHOXYQUINOLINE 4-HYDROXY-8-METHOXYQUINOLINE-3-CARBOXYLIC ACID,4-Hydroxy-8-methoxyquinoline-3-carboxylic acid ,95% 2-HYDROXY-4-METHOXYQUINOLINE 2-Hydroxy-6-methoxyquinoline 4-HYDROXY-5-METHOXYQUINOLINE 6-Methoxyquinoline ETHYL 4-HYDROXY-8-METHOXYQUINOLINE-2-CARBOXYLATE 4-HYDROXY-7-METHOXYQUINOLINE

6-METHOXYQUINOLIN-4(1H)-ONE

6-METHOXYQUINOLIN-4-OL

6-METHOXY-4-QUINOLINOL

6-METHOXY-4(1H)-QUINOLINONE

6-METHOXY-4-HYDROXYQUINOLINE

4-HYDROXY-6-METHOXYQUINOLINE

6-Methoxy-4(1H)-quinolinone([13788-72-2])

Nsc76096

4-Hydroxyl-6-methoxyquinoline

6-Methoxyl-4-quinolinol

6-Methoxyquinoline-4(1H)-one

6-Methoxyquinoline-4-ol

6-Methxoyl-4(1H)-quinolinone

4-Quinolinol, 6-methoxy-

23432-39-5

Quinoline&Isoquinoline