4-HYDROXY-6-METHOXYQUINOLINE
- Product Name
- 4-HYDROXY-6-METHOXYQUINOLINE
- CAS No.
- 23432-39-5
- Chemical Name
- 4-HYDROXY-6-METHOXYQUINOLINE
- Synonyms
- 6-METHOXYQUINOLIN-4-OL;Nsc76096;6-METHOXY-4-QUINOLINOL;6-Methoxyl-4-quinolinol;6-Methoxyquinoline-4-ol;4-Quinolinol, 6-methoxy-;6-METHOXY-4(1H)-QUINOLINONE;6-METHOXYQUINOLIN-4(1H)-ONE;4-HYDROXY-6-METHOXYQUINOLINE;6-METHOXY-4-HYDROXYQUINOLINE
- CBNumber
- CB6149778
- Molecular Formula
- C10H9NO2
- Formula Weight
- 175.18
- MOL File
- 23432-39-5.mol
4-HYDROXY-6-METHOXYQUINOLINE Property
- Melting point:
- 225-244 °C(Solv: water (7732-18-5))
- Boiling point:
- 351.8±22.0 °C(Predicted)
- Density
- 1.258±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 4.40±0.40(Predicted)
- Appearance
- Off-white to gray Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BBO000055
- Product name
- 4-Hydroxy-6-methoxyquinoline
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $259
- Updated
- 2025/07/31
- Product number
- M323608
- Product name
- 6-Methoxyquinolin-4-ol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-W017452
- Product name
- 6-Methoxyquinolin-4-ol
- Purity
- 97.24%
- Packaging
- 1g
- Price
- $13
- Updated
- 2021/12/16
- Product number
- CS-W017452
- Product name
- 6-Methoxyquinolin-4-ol
- Purity
- 97.24%
- Packaging
- 5g
- Price
- $57
- Updated
- 2021/12/16
- Product number
- J97228
- Product name
- 6-Methoxy-4-hydroxyquinoline
- Packaging
- 5g
- Price
- $80
- Updated
- 2021/12/16
4-HYDROXY-6-METHOXYQUINOLINE Chemical Properties,Usage,Production
Synthesis
28027-16-9
23432-39-5
General procedure for the synthesis of 4-hydroxy-6-methoxyquinoline-3-carboxylic acid from 4-hydroxy-6-methoxyquinoline-3-carboxylic acid: 4-hydroxy-6-methoxyquinoline-3-carboxylic acid (7, 15.7 g, 72 mmol) was dissolved in 80 mL of diphenyl ether and heated to 245 °C in a metal bath for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and dissolved in 200 mL of hexane. The mixture was stirred for 3 hours and then filtered. The resulting solid was washed with ethyl acetate and dried to give 6-methoxyquinolin-4-ol (8, 12.5 g, 72 mmol, 100% yield). The product was characterized by 1H-NMR (DMSO-d6): δ= 3.81 (s, 3H), 5.99 (d, 1H), 7.28 (dd, 1H), 7.48-7.53 (m, 2H), 7.86 (d, 1H), 11.87 (bs, 1H).Results of the LC-MS analysis: retention time (Rt) = 0.87 min; mass spectrum (MS): m/z = 176 [M + H]+.
References
[1] Tetrahedron Letters, 2017, vol. 58, # 8, p. 794 - 796
[2] Journal of the American Chemical Society, 1946, vol. 68, p. 1204,1206
[3] Organic Syntheses, 1955, vol. Coll. Vol. III, p. 272
[4] Journal of the American Chemical Society, 1947, vol. 69, p. 1659,1660
[5] Chemical and Pharmaceutical Bulletin, 2007, vol. 55, # 5, p. 821 - 824
4-HYDROXY-6-METHOXYQUINOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
4-HYDROXY-6-METHOXYQUINOLINE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 4-HYDROXY-6-METHOXYQUINOLINE manufacturers
- Product
- 4-HYDROXY-6-METHOXYQUINOLINE 23432-39-5
- Price
- US $10.00/KG/Tin
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100
- Release date
- 2019-06-28