(4-CHLORO-PYRIDIN-2-YL)-METHANOL
- Product Name
- (4-CHLORO-PYRIDIN-2-YL)-METHANOL
- CAS No.
- 63071-10-3
- Chemical Name
- (4-CHLORO-PYRIDIN-2-YL)-METHANOL
- Synonyms
- 4-Chloro-2-pyridylmethanol;CHEMPACIFIC 38138;CHEMBRDG-BB 4014670;4-CHLORO-2-PYRIDINEMETHANOL;4-Chloropyridine-2-methanol;2-Pyridinemethanol, 4-chloro-;(4-chloro-2-pyridinyl) methano;(4-chloro-2-pyridinyl)methanol;4-Chloro-2-pyridinemethanol>(4-Chloropyridine-2-yl)methanol
- CBNumber
- CB6153133
- Molecular Formula
- C6H6ClNO
- Formula Weight
- 143.57
- MOL File
- 63071-10-3.mol
(4-CHLORO-PYRIDIN-2-YL)-METHANOL Property
- Melting point:
- 0°C
- Boiling point:
- 0°C
- Density
- 1.324±0.06 g/cm3(Predicted)
- Flash point:
- 0°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 13.12±0.10(Predicted)
- color
- White to Light yellow to Light orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- ADE000344
- Product name
- (4-Chloro-pyridin-2-yl)-methanol
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $497
- Updated
- 2025/07/31
- Product number
- C2950
- Product name
- 4-Chloro-2-pyridinemethanol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $33
- Updated
- 2025/07/31
- Product number
- C2950
- Product name
- 4-Chloro-2-pyridinemethanol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $132
- Updated
- 2025/07/31
- Product number
- C380635
- Product name
- 4-Chloro-2-pyridinemethanol
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FC75495
- Product name
- 4-Chloro-2-pyridinemethanol
- Packaging
- 10g
- Price
- $130.8
- Updated
- 2021/12/16
(4-CHLORO-PYRIDIN-2-YL)-METHANOL Chemical Properties,Usage,Production
Uses
4-Chloro-2-pyridinemethanol is used in the inactivation of dimethylarginine dimethylaminohydrolase (DDAH).
Synthesis Reference(s)
Synthetic Communications, 19, p. 317, 1989 DOI: 10.1080/00397918908050984
Synthesis
24484-93-3
63071-10-3
General procedure for the synthesis of 4-chloro-2-pyridinemethanol from methyl 4-chloropyridinecarboxylate: Methyl 4-chloropyridinecarboxylate (4.0 g, 23.3 mmol) and CaCl2 (10.3 g, 93.2 mmol) were dissolved in a solvent mixture of anhydrous MeOH-THF (2:1, 30 mL) and cooled to 0 °C. NaBH4 (1.8 g, 46.6 mmol) was added in batches under stirring. The reaction mixture was kept at 0 °C for the reaction. After completion of the reaction, water was added to quench the reaction. The solvent was removed by rotary evaporator and the residue was dissolved in water and extracted with CHCl3. The organic phases were combined, dried over MgSO4, filtered and concentrated by evaporation to give 4-chloro-2-pyridine methanol (3.3 g, 98% yield) as a white solid.
References
[1] Chemical Communications, 2009, # 20, p. 2848 - 2850
[2] Bulletin of the Chemical Society of Japan, 2015, vol. 88, # 6, p. 784 - 791
[3] Synthetic Communications, 2005, vol. 35, # 24, p. 3187 - 3190
[4] Inorganic Chemistry, 2013, vol. 52, # 11, p. 6481 - 6501
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 23, p. 6483 - 6487
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View Lastest Price from (4-CHLORO-PYRIDIN-2-YL)-METHANOL manufacturers
- Product
- (4-CHLORO-PYRIDIN-2-YL)-METHANOL 63071-10-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-26
- Product
- (4-CHLORO-PYRIDIN-2-YL)-METHANOL 63071-10-3
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-09